Magnetic pin for concentrating and separating particles

• US 6,403,038 B1
• Filed: 04/03/2000
• Issued: 06/11/2002
• Est. Priority Date: 07/16/1997
• Status: Expired due to Fees

• Current Assignee: Klaus-Hinrich Heermann
• Original Assignee: Klaus-Hinrich Heermann
• Inventors: Heermann, Klaus-Hinrich
• Primary Examiner(s): Warden, Jill
• Assistant Examiner(s): Sines, Brian J.
• Application Number:
  US09/463,057
• Time in Patent Office: 799 Days
• Field of Search: 422/100, 422/101, 422/99, 422/65, 422/50, 435/287.1, 210/425, 210/695, 294/65.5, 424/1.29, 436/177, 335/285
• US Class Current: 422/527
• CPC Class Codes: B03C 1/01 by addition of magnetic adjuvants
• CPC Class Codes: B03C 1/0332 using permanent magnets
• CPC Class Codes: B03C 1/284 with associated cleaning means, e.g. retractable non-magnetic sleeve
• CPC Class Codes: B03C 1/286 disposed at the inner circumference of a recipient, e.g. magnetic drain bolt
• CPC Class Codes: B03C 2201/18 Magnetic separation whereby the particles are suspended in a liquid
• CPC Class Codes: B03C 2201/26 for use in medical applications
• CPC Class Codes: G01N 33/54326 Magnetic particles
• CPC Class Codes: G01N 35/0098 involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation magnetic particles used in immunoassays G01N33/54326; magnetic separation in general B03C
• CPC Class Codes: G01N 35/10 Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices G01N35/0099 takes precedence

Abstract

The invention relates to a magnetic pin (8, 22) for concentrating particles, containing

(a) a grip adapter (2, 14),

(b) a connecting pin (4, 16) with dents (3, 15),

(c) at least one magnet (7, 20) and

(d) a sheath (5, 18).

Claims

1. Magnetic pin (8, 22) for concentrating particles, comprising:

a connecting pin (4, 16) comprising a rear end and a front end (7, 17) and being provided with a dent (3, 15);

at least one magnet (7, 20) which is arranged at the connecting pin (4, 16), such that a magnetic filed emanates in concentrated fashion at the front end (7, 17); and

a sheath (5, 18) into which the connecting pin (4, 16) can be introduced, which has a conical shape at its lower end, and consists of polymeric plastics and a non-magnetizable, conductive material;

wherein a grip adapter (2, 14) is arranged which serves for operating the magnetic pin (8, 22) through an automatic pipetting machine;

the front end of the connecting pin (4, 16) is provided with a magnetic head (7) which has a conical shape; and

the sheath is moved in associated manner or separately from the connecting pin.

2. The magnetic pin according to claim 1, wherein the grip adapter (2, 14) is made of a deformable material.

3. The magnetic pin according to claim 1 or 2, wherein the grip adapter (2, 14) is developed such that it can be gripped and operated by an industrial automatic pipetting machine.

4. The magnetic pin according to claim 1 or 2, wherein the connecting pin (4, 16) is made of a nonmagnetic material.

5. The magnetic pin according to claim 1 or 2, wherein the magnet (7, 20) is a permanent magnet.

6. The magnetic pin according to claim 1 or 2, wherein the sheath (5, 18) is made of a nonmagnetizable material.

7. The magnetic pin according to claim 1 or 2, wherein the sheath (5, 18) is made of polypropylene.

8. The magnetic pin according to claim 1 or 2, wherein the sheath (5, 18) has a wall thickness of 0.2 to 0.7 mm.

9. The magnetic pin according to claim 1 or 2, wherein the dent (3, 15) has a shape adapted for fixing the sheath (5, 18).

10. The magnetic pin according to claim 1, wherein the connecting pin at the front end comprises the at least one magnet as magnetic head.

11. The magnetic pin according to claim 1, wherein the front end is a tip and the connecting pin has a magnet whose magnetic forces emanate from the tip in beamed fashion.