Non-acidic cyclopentane heptanoic acid,2-cycloalkyl or arylalkyl derivatives as therapeutic agents
DC CAFCFirst Claim
1. A compound, that is cyclopentane N-ethyl heptenamide-5-cis-2-(3α
- -hydroxy-5-phenyl-1-trans-pentenyl)-3,5-dihydroxy, [1α
, 2β
, 3α
, 5α
]).
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Abstract
The present invention provides cydopentane heptanoic acid, 2-cycloalkyl or arylalkyl compounds, which may be substituted in the 1-position with amino, amido, ether or ester groups, e.g., a 1-OH cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compound. The cydopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) compounds of the present invention are potent ocular hypotensives, and are particularly suitable for the management of glaucoma. Moreover, the cydopentane heptanoic, 2-(cycloalkyl or arylalkyl) compounds of this invention are smooth muscle relaxants with broad application in systemic hypertensive and pulmonary diseases; smooth muscle relaxants with application in gastrointestinal disease, reproduction, fertility, incontinence, shock, etc.
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3 Claims
-
1. A compound, that is cyclopentane N-ethyl heptenamide-5-cis-2-(3α
- -hydroxy-5-phenyl-1-trans-pentenyl)-3,5-dihydroxy, [1α
, 2β
, 3α
, 5α
]). - View Dependent Claims (2, 3)
- -hydroxy-5-phenyl-1-trans-pentenyl)-3,5-dihydroxy, [1α
Specification