Extracorporeal blood processing methods and apparatus
First Claim
1. A device for extracorporeal blood processing, comprising:
- a molded cassette member having;
an integral internal fluid passageway in direct fluid communication with both a blood removal conduit means for transferring whole blood from a donor and a blood return conduit means for transferring uncollected blood components to a donor; and
a diaphragm member having an internal-facing side in fluid communication with said internal integral passageway and an external-facing side being externally accessible, said diaphragm member being positionally responsive to pressure changes in said blood removal conduit means and blood return conduit means; and
a pressure-sensing means positionable relative to said cassette member for air coupling with said external-facing side of said diaphragm member of said molded cassette member and for providing an output signal responsive to said pressure changes;
wherein one of said cassette member and said pressure-sensing means comprises an extending portion and the other one of said cassette member and pressure-sensing means comprises a receiving portion, said extending portion and receiving portion being provided for mating engagement with each other to establish said air coupling between said diaphragm and said pressure-sensing means.
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Accused Products
Abstract
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
151 Citations
9 Claims
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1. A device for extracorporeal blood processing, comprising:
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a molded cassette member having;
an integral internal fluid passageway in direct fluid communication with both a blood removal conduit means for transferring whole blood from a donor and a blood return conduit means for transferring uncollected blood components to a donor; and
a diaphragm member having an internal-facing side in fluid communication with said internal integral passageway and an external-facing side being externally accessible, said diaphragm member being positionally responsive to pressure changes in said blood removal conduit means and blood return conduit means; and
a pressure-sensing means positionable relative to said cassette member for air coupling with said external-facing side of said diaphragm member of said molded cassette member and for providing an output signal responsive to said pressure changes;
wherein one of said cassette member and said pressure-sensing means comprises an extending portion and the other one of said cassette member and pressure-sensing means comprises a receiving portion, said extending portion and receiving portion being provided for mating engagement with each other to establish said air coupling between said diaphragm and said pressure-sensing means. - View Dependent Claims (2, 3)
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4. A device for extracorporeal blood processing, comprising:
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a molded cassette member having;
an integral internal fluid passageway in direct fluid communication with both a blood input conduit for transferring whole blood from a donor and a blood output conduit for transferring uncollected blood components to a donor, a diaphragm having a first side in fluid communication with said integral internal fluid passageway and a second side accessible from outside said molded cassette member;
said diaphragm being positionally responsive to pressure changes in said blood input conduit, and said blood output conduit, anda first coupling member which is disposed in extending relationship out from said second side of said diaphragm; and
a pressure sensor assembly having;
a second coupling member to mateably engage with said fist coupling member of said molded cassette member to thereby engage said pressure sensor with said cassette member and to thereby provide an air coupling between said diaphragm and said pressure sensor; and
a pressure sensing member to detect said pressure changes and to provide an output signal in response to said pressure changes. - View Dependent Claims (5, 6, 7, 8, 9)
at least one of said first coupling member and said second coupling member comprises a resilient surface which mateably engages with the other of said first or said second coupling members to provide a sealed engagement between said molded cassette member and said pressure sensor.
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6. A device for extracorporeal blood processing as claimed in claim 4, further comprising:
said first coupling member comprises a nipple end connected to an annular seal for engagement with a cylindrical extension of said second coupling member.
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7. A device for extracorporeal blood processing as claimed in claim 4, further comprising:
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an air channel member connected to said pressure sensing member;
a housing encompassing at least a portion of said air channel member, said air channel member being in a sealed, movable relationship with the interior surface of said housing.
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8. A device for extracorporeal blood processing as claimed in claim 7, wherein:
said air channel member comprises a projecting channel portion containing a resilient seal to provide said sealed relationship with said interior surface of said housing.
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9. A device for extracorporeal blood processing as claimed in claim 7, wherein:
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said interior of said housing is substantially cylindrical;
said air channel member further comprises a cylindrical first section and a cylindrical second section having an annular channel portion; and
a spring in said housing in contact with said annular channel portion to provide a spring loaded interface between said pressure sensor assembly and said molded cassette member.
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Specification