Indwelling heat exchange catheter and method of using same

• US 6,409,747 B1
• Filed: 02/11/2000
• Issued: 06/25/2002
• Est. Priority Date: 04/21/1998
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Alsius Corporation (Asahi Kasei Corporation), Regents of the University of California (University of California)
• Inventors: Jones, Mike, Evans, Scott, Gobin, Yves Pierre, Noda, Wayne
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/503,014
• Time in Patent Office: 865 Days
• Field of Search: 606/192-194, 607/96, 607/104-106, 607/113, 604/101.01, 604/101.05, 604/101.3
• US Class Current: 607/113
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include at least one balloon which is adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. Embodiments including multiple balloons enhance the surface area of contact, and the mixing of both the heat exchange and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body without cooling the entire body system. It is of particular advantage in brain surgeries where stroke, trauma or cryogenic tumors can best be addressed under hypothermic conditions.

Claims

1. A catheter comprising:

a shaft having an axis extending between a proximal end and a distal end, the shaft having at least one input lumen and at least one output lumen;

a heat exchange region disposed substantially at the distal end of the shaft and including at least a first balloon and at least a second balloon each having an outer surface;

the input lumen of the shaft being coupled to the first balloon at a first location, and the output lumen of the shaft being coupled to the first balloon at a second location so that a heat exchange fluid introduced into the input lumen will enter the first balloon at the first location and will exit the first balloon at the second location through the output lumen.

2. The catheter of claim 1, the first location and second location being disposed along a first direction in a body conduit in which body fluid is flowing when the catheter is operatively disposed in the body fluid.

3. The catheter of claim 1, wherein the input lumen and the output lumen are also coupled to the second balloon.

6. The catheter of claim 3, wherein the first outlet hole is larger than the first inlet hole.

4. A heat exchange catheter, comprising:

a shaft having an axis, at least one fluid input lumen, and at least one fluid output lumen;

a hub disposed proximally on the shaft and providing access to the fluid input lumen and the fluid output lumen;

a first balloon disposed distally on the shaft and defining with the shaft an inflatable first cavity;

a second balloon disposed on the shaft and defining with the shaft an inflatable second cavity; and

the input lumen and output lumen communicating with the cavities.

5. The catheter of claim 4, the shaft defining a first inlet hole for establishing fluid communication between the fluid input lumen and the first cavity;

and

the shaft defining a first outlet hole for establishing fluid communication between the first cavity and the fluid output lumen.

7. A catheter comprising:

a shaft having an axis extending between a proximal end and a distal end, the shaft having at least one input lumen and at least one output lumen;

a heat exchange region disposed substantially at the distal end of the shaft and including a first balloon, a second balloon and a third balloon each having an outer surface;

the input lumen of the shaft being coupled to the first balloon at a first location, and the output lumen of the shaft being coupled to the first balloon at a second location so that a heat exchange fluid introduced into the input lumen will enter the first balloon at the first location and will exit the first balloon at the second location through the output lumen.