Chemotherapeutic treatment of bacterial infections with an antibiotic encapsulated within a biodegradable polymeric matrix
First Claim
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1. A method for the protection against or therapeutic treatment of bacterial infection in the tissue of a human or nonhuman animal comprising administering locally to said animal a bactericidally-effective amount of a pharmaceutical composition consisting essentially of an antibiotic encapsulated within a biodegradable comprising poly (DL-lactide-co-glycolide) matrix wherein the duration of controlled release of the antibiotic is within a period of about 14 days to about 6 weeks.
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Abstract
Biodegradable pharmaceutical compositions and method for treating bacterial infections therein.
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47 Claims
- 1. A method for the protection against or therapeutic treatment of bacterial infection in the tissue of a human or nonhuman animal comprising administering locally to said animal a bactericidally-effective amount of a pharmaceutical composition consisting essentially of an antibiotic encapsulated within a biodegradable comprising poly (DL-lactide-co-glycolide) matrix wherein the duration of controlled release of the antibiotic is within a period of about 14 days to about 6 weeks.
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30. A pharmaceutical composition useful in the effective treatment of an animal with infected wound in the soft-tissue a bone consisting essentially of an antibiotic encapsulated within a biodegradable comprising poly (DL-lactide-co-glycolide) matrix wherein the controlled release rate of the antibiotic is within a period of about 14 days to about 6 weeks.
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