Antimicrobial composition containing parachlorometaxylenol (PCMX)
First Claim
1. An antimicrobial composition for disinfecting a skin surface comprising:
- a) parachlorometaxylenol in an amount of about 3% to about 4% by weight;
b) an anionic surfactant composition consisting essentially of sodium C12-15 pareth-15 sulfonate, sarcosine surfactant, and sodium lauryl sulfate; and
c) an emollient.
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Accused Products
Abstract
The present invention provides an antimicrobial composition for disinfection of a skin surface in preparation for surgery. The antimicrobial composition comprises parachlorometaxylenol (PCMX) and an anionic surfactant composition which exhibits both a high degree of antimicrobial efficacy and low skin irritability properties. In a preferred embodiment, the composition comprises an anionic surfactant composition comprising a surfactant having a hydrophobic portion consisting of a linear alkyl and a hydrophilic portion having ethoxylation termination with a sulfonate anionic group, and a sarcosine surfactant. A preferred surfactant composition further comprises a foaming anionic surfactant, such as sodium lauryl sulfate. The antimicrobial composition can be used in skin disinfecting formulations, such as scrub formulations and pre-operative skin disinfecting formulations. In one embodiment, the composition comprises about 3.3% parachlorometaxylenol. The composition can be used as a surgical scrub formulation or in various pre-surgical skin disinfecting products, including sponges, swabs and topical application devices.
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Citations
21 Claims
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1. An antimicrobial composition for disinfecting a skin surface comprising:
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a) parachlorometaxylenol in an amount of about 3% to about 4% by weight;
b) an anionic surfactant composition consisting essentially of sodium C12-15 pareth-15 sulfonate, sarcosine surfactant, and sodium lauryl sulfate; and
c) an emollient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 13, 14, 15, 16, 21)
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10. An antimicrobial composition for disinfection of a skin surface consisting essentially of:
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a) parachlorometaxylenol in an amount from about 3% to about 4% by weight;
b) sodium C12-15 pareth-15 sulfonate;
c) sodium lauroyl sarcosinate;
d) sodium lauryl sulfate;
e) an emollient;
f) a solvent system comprising water and a phenolic-compatible solvent; and
g) a viscosity enhancer. - View Dependent Claims (11)
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12. An antimicrobial composition consisting essentially of:
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a) parachlorometaxylenol in an amount of about 3.3% by weight;
b) sodium C12-15 pareth-15 sulfonate in an amount of about 6.3% by weight;
c) sodium lauroyl sarcosinate in an amount of about 3.0% by weight;
d) sodium lauryl sulfate in an amount of about 1.05% by weight;
e) soy acid in an amount of about 0.3% by weight;
f) propylene glycol in an amount of about 9.0% by weight;
g) PEG-120 methyl glucose dioleate in an amount of about 3.0% by weight;
h) water in an amount of about 72.47% by weight;
i) phenoxyethanol in an amount of about 1.0% by weight;
j) citric acid in an amount of about 0.26% by weight;
k) sodium hydroxide in an amount of about 0.02% by weight;
l) styrene/PVP co-polymer in an amount of about 0.3% by weight.
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17. A method of disinfecting skin comprising applying to the skin surface to be disinfected an antiseptically effective amount of an antimicrobial composition comprising:
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a) parachlorometaxylenol in an amount of about 3% to about 4% by weight; and
b) an anionic surfactant composition consisting essentially of sodium C12-15 pareth-15 sulfonate, sarcosine surfactant, and sodium lauryl sulfate; and
c) an emollient. - View Dependent Claims (18, 19, 20)
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Specification