Hair loss prevention

• US 6,420,352 B1
• Filed: 01/11/2002
• Issued: 07/16/2002
• Est. Priority Date: 07/19/2000
• Status: Expired due to Fees

• Current Assignee: Knowles W. Roy
• Original Assignee: Knowles W. Roy
• Inventors: Knowles, W. Roy
• Primary Examiner(s): Criares, Theodore J.
• Assistant Examiner(s): KIM, VICKIE Y
• Application Number:
  US10/044,553
• Publication Number:
  US 20020086873A1
• Time in Patent Office: 186 Days
• Field of Search: 514/171, 514/255.05, 514/255.06
• US Class Current: 514/171
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 8/4953 containing pyrimidine ring derivatives, e.g. minoxidil
• CPC Class Codes: A61Q 7/00 Preparations for affecting hair growth

Abstract

Compositions to prevent or reduce hair loss, allowing the body to maintain normal, healthy hair growth, comprising a penetration enhancer together with a testosterone blocker or a vascular enhancer, or both.

Claims

1. A topical composition of matter comprising:

a) a 5α

-reductase inhibitor,

b) minoxidil, and

c) trimethyl acetate.

2. The composition of claim 1, wherein said trimethyl acetate is present in a concentration sufficient to aid in penetrating skin to a depth of approximately the depth of hair bulbs.

3. The composition of claim 1, wherein said 5α

-reductase inhibitor comprises progesterone.

4. The composition of claim 3, wherein the ratio of 5α

-reductase inhibitor to minoxidil in the composition is approximately 0.5 grams;

1 gram.

5. An article of manufacture comprising:

a) the composition of claim 3, and

b) a label indicating cosmetic use.

6. An article of manufacture comprising:

a) the composition of claim 3, and

b) a label indicating pharmaceutical use.

7. The article of manufacture of claim 6, wherein said pharmaceutical use comprises alopecia.

8. The composition of claim 3, further comprising a sunscreen.

9. A method comprising topically administering a composition of matter comprising:

a) a 5α

-reductase inhibitor,

b) minoxidil, and

c) trimethyl acetate.

10. The method of claim 9, wherein said trimethyl acetate is present in a concentration sufficient to aid in penetrating skin to a depth of approximately the depth of hair bulbs.

11. The method of claim 9, wherein said 5α

-reductase inhibitor comprises progesterone.

12. The method of claim 11, wherein the ratio of 5α

-reductase inhibitor to minoxidil in the composition is approximately 0.5 grams;

1 gram.

13. The method of claim 9, used for a cosmetic use.

14. The method of claim 9, used for a pharmaceutical use.

15. The method of claim 14, wherein said pharmaceutical use is preventing or treating alopecia.

16. The method of claim 11, further comprising administering a sunscreen.

17. A method for improving the skin penetration of a topically-applied compound, the method comprising topically administering said compound together with trimethyl acetate.