Method for intravascular radioactive treatment

• US 6,422,989 B1
• Filed: 11/05/1999
• Issued: 07/23/2002
• Est. Priority Date: 05/30/1997
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Hektner, Thomas R.
• Primary Examiner(s): Lacyk, John P.
• Application Number:
  US09/434,744
• Time in Patent Office: 991 Days
• Field of Search: 600/1-7
• US Class Current: 600/3
• CPC Class Codes: A61N 2005/1008 Apparatus for temporary insertion of sources, e.g. afterloaders
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

A device, system and method for delivering radiation to interior body sites, including stenosed blood vessel regions for the purpose of inhibiting restenosis after angioplasty. A string having a radioactive first region, a second region, and an intermediate region is disposed within or along an elongate shaft having a distal return member. The string intermediate portion is typically initially looped over the distal return member. The radioactive region is normally initially disposed within a radiation shielding vault or enclosure. The elongate shaft can be advanced within a vessel to the site to be treated, followed by pulling the string to advance the string radioactive region within the shaft to the treatment site. After exposure, the string can be retracted, placing the radioactive string region back within the vault. The string can be used and re-used without sterilization when used within catheter lumens not in fluid communication with bodily fluids.

Claims

1. A method for irradiating a body interior region comprising the steps:

providing a radiation delivery device including

an elongate shaft member having a proximal region and a distal region, said distal region including a string return member, and

a string within said shaft having a first region extending distally from the proximal region, a second region extending proximally from said distal region, an intermediate region between said first and second regions, and radioactive material affixed to said first region;

advancing said elongate shaft distal region to said treatment site;

advancing said string radioactive portion to said shaft distal region by pulling said string proximally past said string return member;

irradiating said treatment site; and

retracting said string radioactive portion proximally.

2. A method for irradiating as recited in claim 1, wherein said string retracting step includes pulling said string radioactive portion proximally relative to said elongate shaft.

3. A method for irradiating as recited in claim 1, wherein said radiation delivery device includes a radiation shielding enclosure having an aperture for receiving said string radioactive first region, wherein said string A-retracting step includes retracting said string radioactive first region into said enclosure.

4. A method for irradiating as recited in claim 1, wherein said radiation delivery device includes a radiation shielding enclosure having an aperture for receiving said elongate shaft proximal region, wherein said string retracting step includes retracting said elongate shaft proximal region into said enclosure.

5. A method for irradiating as recited in claim 1, wherein said provided radiation delivery device elongate shaft member includes

a lumen therethrough adapted to receive said string, said lumen being in communication with said return member,

an exterior in fluid communication with said body, and

an interior isolated from fluid communication with said body, said interior including said lumen and containing said return member such that said string is not in fluid communication with said body.