Oscillometric blood pressure monitor with improved performance in the presence of arrhythmias

• US 6,423,010 B1
• Filed: 10/04/2000
• Issued: 07/23/2002
• Est. Priority Date: 10/04/2000
• Status: Expired due to Term

• Current Assignee: GE Medical Systems Information Technologies Incorporated (GE Healthcare Technologies, Inc.)
• Original Assignee: Critikon Co. LLC (GE Aerospace)
• Inventors: Dedyo, Christopher J., Hersh, Lawrence T., Friedman, Bruce
• Primary Examiner(s): Shaver, Kevin
• Assistant Examiner(s): MALLARI, PATRICIA C
• Application Number:
  US09/678,650
• Time in Patent Office: 657 Days
• Field of Search: 600/493-496, 600/490
• US Class Current: 600/494
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/33 specially adapted for cooperation with other devices

Abstract

The present invention relates to an improved apparatus and method for measuring blood pressure. Both include a first sensor for detecting an instantaneous pulse rate, an inflatable cuff, and a second sensor to monitoring the pressure within the cuff. The cuff sensor adapted to detect oscillometric complexes associated with a patient'"'"'s pulse. Both the apparatus and the method provide for detecting arrhythmia from the patient'"'"'s instantaneous pulse rate. A characteristic of the oscillometric complexes is measured, and match determination means provided for determining whether at least two adjacent oscillometric complexes are equivalent. A first set matching criteria are used under normal conditions. A second set of matching criteria are used when arrhythmia are detected. A controller is provided for controlling the pressure within the cuff. At the outset of a blood pressure measurement the cuff is inflated to a pressure greater than the patient'"'"'s systolic pressure. In response to a determination that two adjacent oscillometric complexes are equivalent the control means reduces the cuff pressure by a fixed increment and the match determination means continues to determine whether adjacent complexes are equivalent. A blood pressure determination means is provided responsive to the control means and the measuring means. The blood pressure determination means compares the measured characteristic of the oscillometric complexes from various cuff pressures and determines the cuff pressure at which the measured characteristic reaches a limit. This cuff pressure corresponds to the patient'"'"'s mean arterial pressure.

Claims

1. A method for measuring a patient'"'"'s blood pressure comprising the steps of:

applying an inflatable cuff around an extremity of said patient;

inflating said cuff to a pressure above said patient'"'"'s systolic blood pressure;

detecting oscillation complexes within said cuff;

measuring a characteristic of said oscillation complexes;

establishing first and second sets of matching criteria based on said measured characteristic of said oscillation complexes for determining whether adjacent oscillation complexes are equivalent;

providing a sensor to detect the presence of arrhythmias;

comparing adjacent complexes to determine whether said oscillation complexes are equivalent according to said first set of matching criteria when an arrhythmia has not been detected and according to said second set of matching criteria when an arrhythmia has been detected;

upon detecting equivalent adjacent complexes, deflating said cuff pressure by a predetermined increment and again detecting oscillation complexes within said cuff, measuring said characteristic of said oscillation complexes, and comparing said characteristic of adjacent oscillation complexes to determine whether any two adjacent oscillation complexes are equivalent;

repeating the preceding step until it is determined that the measured characteristic of two equivalent adjacent oscillation complexes at a given cuff pressure has reached a maximum relative to the measured characteristic of the two adjacent equivalent oscillation complexes measured at other cuff pressures, the given cuff pressure at which said measured characteristic reaches a maximum corresponding to the patient'"'"'s mean arterial pressure.

2. The method of claim 1 wherein the step of providing a second sensor comprises providing an ECG monitor.

3. The method of claim 1 wherein the step of providing a second sensor comprises providing a blood volume sensor.

4. The method of claim 3 wherein said blood volume sensor comprises a blood oximeter.

5. The method of claim 3 wherein the step of providing a second sensor further comprises providing an ECG monitor.

6. The method of claim 1 wherein the step of establishing first and second sets of matching criteria comprises establishing a first peak pulse amplitude variation threshold such that oscillometric complexes having peak pulse amplitudes that differ by an amount less than said first amplitude variation threshold are considered equivalent according to said first set of matching criteria.

7. The method of claim 6 wherein said first amplitude variation threshold comprises 12%.

8. The method of claim 6 wherein the step of establishing first and second sets of matching criteria further comprises establishing a second amplitude variation threshold such that oscillometric complexes having amplitudes that differ by an amount less than said second amplitude variation threshold are considered equivalent according to said second set of matching criteria.

9. The method of claim 8 wherein said second amplitude variation threshold comprises 24%.

10. The method of claim 1 wherein the step of establishing first and second sets of matching criteria comprises establishing a first period variation threshold such that when the period between a first oscillometric complex and an immediately preceding oscillometric complex and the period between a second oscillometric complex and the first oscillometric complex differ by an amount less than said first period variation threshold said oscillometric complexes are considered equivalent according to said first set of matching criteria.

11. The method of claim 10 wherein said first period variation threshold comprises 25%.

12. The method of claim 10 wherein the step of establishing first and second sets of matching criteria further comprises establishing a second period variation threshold such that when the period between a first oscillometric complex and an immediately preceding oscillometric complex and the period between a second oscillometric complex and the first oscillometric complex differ by an amount less than said second period variation threshold said oscillometric complexes are considered equivalent according to said second set of matching criteria.

13. The method of claim 12 wherein said second period variation threshold comprises 50%.

14. The method of claim 1 wherein the step of establishing first and second sets of matching criteria further comprises establishing a first amplitude variation threshold and a first period variation threshold such that first and second oscillometric complexes having amplitudes that differ by an amount less than said first amplitude variation threshold and the period between the first oscillometric complex and an immediately preceding oscillometric complex and the period between the second oscillometric complex and the first oscillometric complex differ by an amount less than said first period variation threshold, the first and second oscillometric complexes are considered equivalent according to the first set of matching criteria.

15. The method of claim 1 wherein the step of establishing first and second sets of matching criteria further comprises establishing a second amplitude variation threshold and a second period variation threshold such that first and second oscillometric complexes having amplitudes that differ by an amount less than said second amplitude variation threshold and the period between the first oscillometric complex and an immediately preceding oscillometric complex and the period between the second oscillometric complex and the first oscillometric complex differ by an amount less than said second period variation threshold, the first and second oscillometric complexes are considered equivalent according to the second set of matching criteria.

16. An apparatus for measuring blood pressure comprising:

a first sensor for detecting an instantaneous pulse rate;

an inflatable cuff;

a second sensor associated with the inflatable cuff configured to monitor the pressure within said cuff, including detecting oscillometric complexes associated with a patient'"'"'s pulse when said cuff is inflated around an extremity of said patient;

arrhythmia detection means for detecting the presence of arrhythmias from said instantaneous pulse rate;

measuring means for measuring a characteristic of said oscillometric complexes;

match determination means for determining whether at least two adjacent oscillometric complexes associated with adjacent cardiac pulses are equivalent based on matching criteria related to said measured characteristic, said match determination means employing a second set of matching criteria when said arrhythmia detection means determines that at least one of the oscillometric complexes being compared is associated with an arrhythmia, and employing a first set of matching criteria otherwise;

control means for controlling the pressure within said cuff responsive to said match determination means such that, at the outset of a blood pressure measurement, said cuff is inflated to a pressure greater than the patient'"'"'s systolic pressure, in response to a determination that two adjacent oscillometric complexes are equivalent, said control means reducing the cuff pressure by a fixed increment, whereupon said match determination means continues to determine whether adjacent complexes are equivalent; and

blood pressure determination means responsive to said control means and said measuring means, said blood pressure determination means comparing the measured characteristic of the oscillometric complexes obtained at the various incremental cuff pressures and determining the cuff pressure at which said measured characteristic reaches a limit, said cuff pressure at which said measured characteristic reaches said limit corresponding to the patient'"'"'s mean arterial pressure.

17. The apparatus of claim 16 wherein said first sensor comprises an ECG monitor.

18. The apparatus of claim 16 wherein the first sensor comprises a blood volume sensor.

19. The apparatus of claim 18 wherein said blood volume sensor comprises a pulse oximeter.

20. The apparatus of claim 18 wherein the first sensor further comprises an ECG monitor.

21. The apparatus of claim 16 wherein first and second sets of matching criteria comprise first and second amplitude variation thresholds such that oscillometric complexes having amplitudes that differ by an amount less than said first amplitude variation threshold are considered equivalent according to said first set of matching criteria, and oscillometric complexes having amplitudes that differ by an amount less than said second amplitude variation threshold are considered equivalent according to said second set of matching criteria.

22. The method of claim 21 wherein said first amplitude variation threshold comprises 12%.

23. The apparatus of claim 22 wherein said second amplitude variation threshold comprises 24%.

24. The apparatus of claim 16 wherein the first and second sets of matching criteria comprise first and second period variation thresholds such that when the period between a first oscillometric complex and an immediately preceding oscillometric complex and the period between a second oscillometric complex and the first oscillometric complex differ by an amount less than said first period variation threshold said oscillometric complexes are considered equivalent according to said first set of matching criteria, and when the period between the first oscillometric complex and the immediately preceding oscillometric complex and the period between the second oscillometric complex and the first oscillometric complex differ by an amount less than said second period variation threshold, said oscillometric complexes are considered equivalent according to said second set of matching criteria.

25. The apparatus of claim 24 wherein said first period variation threshold comprises 25%.

26. The apparatus of claim 25 wherein said second period variation threshold comprises 50%.

27. The apparatus of claim 16 wherein the first set of matching criteria comprises a first amplitude variation threshold and a first period variation threshold such that first and second oscillometric complexes having amplitudes that differ by an amount less than said first amplitude variation threshold and the period between the first oscillometric complex and an immediately preceding oscillometric complex and the period between the second oscillometric complex and the first oscillometric complex differ by an amount less than said first period variation threshold, the first and second oscillometric complexes are considered equivalent according to the first set of matching criteria, and the second set of matching criteria comprises a second amplitude variation threshold and a second period variation threshold such that first and second oscillometric complexes having amplitudes that differ by an amount less than said second amplitude variation threshold and the period between the first oscillometric complex and an immediately preceding oscillometric complex and the period between the second oscillometric complex and the first oscillometric complex differ by an amount less than said second period variation threshold, the first and second oscillometric complexes are considered equivalent according to the second set of matching criteria.

28. A method of rejecting artifacts and compensating for non-sinus beats when performing an oscillometric blood pressure measurement using an inflatable cuff whereby oscillometric complexes are detected at a plurality of incremental cuff pressures, the method of rejecting artifacts comprising the steps of:

providing a first sensor for monitoring a patient'"'"'s sinus rhythm and detecting non-sinus beats;

providing a second sensor for detecting oscillometric complexes associated with each beat of the patient'"'"'s pulse;

measuring a characteristic of said oscillation complexes at each incremental cuff pressure;

comparing said characteristic measured from oscillation complexes associated with adjacent pulses to determine whether said oscillometric complexes are equivalent based on specific matching criteria;

proceeding to the next incremental cuff pressure when it has been determined that two adjacent oscillometric complexes are equivalent; and

relaxing the matching criteria when comparing the measured characteristic of oscillometric complexes obtained when non-sinus beats are detected.

29. The method of claim 28 wherein the step of providing a first sensor comprises providing an ECG monitor.

30. The method of claim 28 wherein the step of providing a first sensor comprises providing a blood volume sensor.

31. The method of claim 30 wherein said blood volume sensor comprises a pulse oximeter.

32. The method of claim 28 wherein the step of comparing a characteristic of said oscillation complexes comprises comparing the amplitude of said oscillation complexes.

33. The method of claim 32 wherein the step of relaxing the matching criteria comprises allowing oscillation complexes having greater amplitude variations to be considered equivalent.

34. The method of claim 32 wherein the step of relaxing the matching criteria comprises considering oscillation complexes having greater variance in the period between adjacent complexes to be considered equivalent.