Device and method for embolus detection

• US 6,425,866 B1
• Filed: 01/29/2000
• Issued: 07/30/2002
• Est. Priority Date: 07/31/1997
• Status: Expired due to Term

• Current Assignee: Compumedics Germany GmbH
• Original Assignee: DWL Elektronische Systeme GmbH (Compumedics Limited)
• Inventors: Denner, Dieter, Brucher, Rainer
• Primary Examiner(s): Jaworski, Francis J.
• Application Number:
  US09/463,816
• Time in Patent Office: 913 Days
• Field of Search: 600/437, 600/438, 128/DIG.13, 73/614.9, 738/655, 736/00
• US Class Current: 600/438
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/0808 for diagnosis of the brain
• CPC Class Codes: Y10S 128/13 Infusion monitoring

Abstract

A device for detecting embolus uses ultrasonic signals reflected on a fluid flow in a body. The device features a first ultrasonic unit for receiving a first signal generated in a first position in a vessel and a second ultrasonic unit for additional reception of a second signal generated in a second position in the body. The device also features a detector unit for detecting the embolus. The detector unit is triggered only if the time interval between the characteristic changes in the first and second signal, corresponding to a possible embolus, exceeds a minimum value, or if the characteristic signal change occurs in one of the signals only.

Claims

1. A device for embolus detection by means of ultrasonic signals which are reflected at a flow of fluid in a body, comprising:

an ultrasonic unit which is adapted for periodically producing ultrasonic monitoring signals for a suitably designed ultrasonic transmitting device and for receiving a first signal reflected at a first position corresponding to the flow of fluid in a vessel;

a signal evaluation unit which is connected downstream of the ultrasonic unit for preparing and visually and/or acoustically providing the reflected first signal;

a detector unit which co-operates with the signal evaluation unit and which is adapted to detect an embolus in the flow of fluid and to output a detection signal as a reaction thereto;

wherein the ultrasonic unit is designed for additionally receiving a second signal from the ultrasonic transmitting device, which is reflected at a second position in the body that lies outside the vessel and the flow fluid; and

the detector unit is designed to detect an embolus as a reaction to the first and the second signal in such a way that output of the detection signal occurs only if a characteristic signal change, corresponding to a possible embolus, in one of the first and second signals occurs outside a minimum time interval from a signal change in the respective other signal, or the characteristic signal change occurs in only one of the signals.

2. The device set forth in claim 1 wherein the minimum time interval is three msec.

3. The device set forth in claim 1 wherein the ultrasonic unit is so adapted that the second signal is generated at a moment in time which is different from the first signal in accordance with a different depth of penetration of the ultrasonic signal into the body, from a common transmission signal.

4. The device set forth in claim 1 wherein the first signal is produced from a first ultrasonic probe unit as a signal source and the second signal is produced from a second ultrasonic probe unit as a further signal source.

5. The device set forth in claim 1 wherein the ultrasonic unit is so adapted that the second position is in the head region and at a depth, relative to an associated ultrasonic transducer, of between about 30 and 35 mm, and the first position is at a depth of greater than 40 mm.

6. The device set forth in claim 1 wherein the ultrasonic unit on the receiving side is of a multi-channel configuration with a plurality of receiving units which are adapted to output discrete signal states of the first and/or the second signal and which can be controlled in time-displaced relationship as a reaction to a common transmission signal.

7. The device set forth in claim 1 wherein the detector unit implements processing of the first and the second signals for detecting the embolus in the time domain.

8. The device set forth in claim 1 wherein the detector unit is so adapted that processing of the first and the second signals for detecting the embolus is effected on the basis of at least one signal which is transformed into the frequency domain.

9. A method of embolus detection by way of ultrasonic signals which are reflected at a flow of fluid in a body, comprising the following steps:

periodically emitting ultrasonic vessel monitoring signals by way of a suitably adapted probe;

receiving and preparing the signals reflected at a flow of fluid in a vessel to be observed, and

evaluating the prepared signals and outputting a detection signal for a detected embolus as a reaction to the received signals;

additionally receiving a reference signal which is reflected at a position in the body outside the vessel to be observed; and

comparing the reference signal to the signals reflected at the flow of fluid and determining an embolus as a reaction to the existence of a characteristic signal change, corresponding to an embolus, in the reference signal and/or as a reaction to a time interval between the characteristic signal change in the reference signal and a corresponding signal change in the signals reflected at the flow of fluid.