Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
First Claim
1. A method for contrast enhanced NMR or x-ray lymphography imaging in a human or animal which comprises administering a contrast enhancement effective amount of a contrast agent to the human or animal and generating an enhanced image by NMR or x-ray of at least a part of the lymphatic system thereof, wherein said contrast agent is a nitrogen-containing cascade polymer having complexing ligands which complex at least 16 ions of an element of atomic numbers 20-29, 39, 42, 44 or 57-83, provided that the cascade polymer is not bound to macromolecules or biomolecules for targeting the lymphatic system.
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Abstract
Cascade polmer complexes with at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83, useful NMR or x-ray lymphography imaging.
19 Citations
9 Claims
- 1. A method for contrast enhanced NMR or x-ray lymphography imaging in a human or animal which comprises administering a contrast enhancement effective amount of a contrast agent to the human or animal and generating an enhanced image by NMR or x-ray of at least a part of the lymphatic system thereof, wherein said contrast agent is a nitrogen-containing cascade polymer having complexing ligands which complex at least 16 ions of an element of atomic numbers 20-29, 39, 42, 44 or 57-83, provided that the cascade polymer is not bound to macromolecules or biomolecules for targeting the lymphatic system.
Specification