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Sustained-release theophylline tablet

  • US 6,426,091 B1
  • Filed: 03/21/2000
  • Issued: 07/30/2002
  • Est. Priority Date: 09/30/1997
  • Status: Expired due to Fees
First Claim
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1. A theophylline sustained release tablet comprising (i) core granules having a theophylline content of 98% or more, (ii) at least one coating film layer composed of a hydrophobic material, and a plastic excipient to form coated granules and (iii) a disintegrating excipient, and coated granules and said disintegrating excipient being compression molded to form the theophylline sustained release tablet, wherein the sustained release action is obtained by the tablet disintegrating into the coated granules that are dispersed immediately and the theophylline is gradually dissolved from the dispersed coated granules.

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