Aneurysm embolization device

• US 6,428,558 B1
• Filed: 02/16/2000
• Issued: 08/06/2002
• Est. Priority Date: 03/10/1999
• Status: Expired due to Term

• Current Assignee: Codman & Shurtleff Incorporated (Johnson & Johnson)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Mitelberg, Vladimir, Jones, Donald K.
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US09/505,231
• Time in Patent Office: 902 Days
• Field of Search: 606/108, 606/200, 606/151, 606/191, 606/127, 606/114, 606/159, 604/105, 604/107
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

An aneurysm embolization device which may be used to occlude a blood vessel or aneurysm. The device has a plurality of support struts which form a substantially ellipsoidal shape. The support struts are preferably formed from a nickel-titanium alloy, such as nitinol, which has superelastic characteristics. A mesh sleeve is disposed over the support struts. The mesh sleeve is preferably formed of a thrombogenic material, such as polyurethane, so as to encourage the formation of blood clots and scar tissue to permanently occlude the vessel.

Claims

1. An embolization device deployment system comprising:

a catheter having a proximal end, a distal end, and a lumen extending throughout the length of the catheter;

an embolization device comprising a plurality of arcuate support struts, said support struts being connected to each other to form a structure of a substantially ellipsoidal configuration, said embolization device further comprising a mesh sleeve disposed over and attached to said support struts, said embolization device being slidingly disposed within the lumen at the distal end of the catheter;

a hub having a lumen extending therethrough, said hub being mounted on the proximal end of the catheter and the lumen of the hub communicating with the lumen of the catheter; and

,

a pusher mechanism disposed through the lumen of the hub and the lumen of the catheter, said pusher mechanism being used to displace said embolization device from within the lumen at the distal end of the catheter to thereby deploy said embolization device within a blood vessel.

2. An embolization device deployment system as defined in claim 1, wherein said support struts have a proximal end and a distal end, said supports struts being attached at least one end and biased outwardly to form a substantially ellipsoidal structure.

3. An embolization device deployment system as defined in claim 2, wherein said support struts are formed from a superelastic alloy and said mesh sleeve is formed from a thrombogenic material.

4. An embolization device deployment system as defined in claim 3, wherein said alloy is formed from nickel and titanium.

5. An embolization device deployment system as defined in claim 4, wherein said alloy is comprised of at least about 51% nickel and at least about 44% titanium.

6. An embolization device deployment system as defined in claim 3, wherein said thrombogenic material is comprised of polyurethane, said support struts are coated with a layer of polyurethane material, and said mesh sleeve is heat fused to said support struts.

7. An embolization device deployment system as defined in claim 6, wherein said layer of polyurethane material includes a radiopaque compound.

8. An embolization device deployment system as defined in claim 7, wherein said radiopaque compound is comprised of tantalum.

9. An embolization device deployment system comprising:

a catheter having a proximal end, a distal end, and a lumen extending throughout the length of the catheter;

an embolization device comprising a plurality of arcuate support struts, said support struts having a proximal end and a distal end, said supports struts being attached at the proximal and distal ends and biased outwardly to form a substantially ellipsoidal structure, said embolization device further comprising a mesh sleeve disposed over and attached to said support struts, said embolization device being slidingly disposed within the lumen of the distal end of the catheter;

a hub having a lumen extending therethrough, said hub being mounted on the proximal end of the catheter and the lumen of the hub communicating with the lumen of the catheter; and

,

a pusher mechanism disposed through the lumen of the hub and the lumen of the catheter, said pusher mechanism being used to displace said embolization device from within the lumen at the distal end of the catheter to thereby deploy said embolization device within a blood vessel.

10. An embolization device deployment system as defined in claim 9, wherein said support struts are formed from a superelastic alloy and said mesh sleeve is formed from a thrombogenic material.

11. An embolization device deployment system as defined in claim 10, wherein said alloy is comprised of nickel and titanium.

12. An embolization device deployment system as defined in claim 11, wherein said alloy is comprised of at least about 51% nickel and at least about 44% titanium.

13. An embolization device deployment system as defined in claim 10, wherein said thrombogenic material is comprised of polyurethane, said support struts are coated with a layer of polyurethane material, and said mesh sleeve is heat fused to said support struts.

14. An embolization device deployment system as defined in claim 13, wherein said layer of polyurethane material includes a radiopaque compound.

15. An embolization device deployment system as defined in claim 14, wherein said radiopaque compound is comprised of tantalum.

16. An embolization device deployment system comprising:

a catheter having a proximal end, a distal end, and a lumen extending throughout the length of the catheter;

an embolization device comprising a plurality of arcuate support struts, said support struts being comprised of a tube, said tube having a tubular wall and a lumen extending therethrough, said tube further having a proximal end, a distal end, and a plurality of longitudinal cuts through the wall of the tube, said cuts extending from a point near the proximal end of the tube and extending to a point near the distal end of the tube, said support struts being biased outwardly to form a substantially ellipsoidal structure, said embolization device further comprising a mesh sleeve disposed over and attached to said support struts, said embolization device being slidingly disposed within the lumen of the distal end of the catheter;

a hub having a lumen extending therethrough, said hub being mounted on the proximal end of the catheter and the lumen of the hub communicating with the lumen of the catheter; and

,

a pusher mechanism disposed through the lumen of the hub and the lumen of the catheter, said pusher mechanism being used to displace said embolization device from within the lumen at the distal end of the catheter to thereby deploy said embolization device within a blood vessel.

17. An embolization device deployment system as defined in claim 16, wherein said support struts are formed from a superelastic alloy and said mesh sleeve is formed from a thrombogenic material.

18. An embolization device deployment system as defined in claim 17, wherein said alloy is comprised of nickel and titanium.

19. An embolization device deployment system as defined in claim 18, wherein said alloy is comprised of at least about 51% nickel and at least about 44% titanium.

20. An embolization device deployment system as defined in claim 17, wherein said thrombogenic material is comprised of polyurethane, said support struts are coated with a layer of polyurethane material, and said mesh sleeve is heat fused to said support struts.

21. An embolization device deployment system as defined in claim 20, wherein said layer of polyurethane material includes a radiopaque compound.

22. An embolization device deployment system as defined in claim 21, wherein said radiopaque compound is comprised of tantalum.