Biosensor

• US 6,428,664 B1
• Filed: 06/19/2000
• Issued: 08/06/2002
• Est. Priority Date: 06/19/2000
• Status: Expired due to Term

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Corporation (Roche Holding AG)
• Inventors: Bhullar, Raghbir Singh, Walling, Douglas Paul
• Primary Examiner(s): Tung, T.
• Assistant Examiner(s): NOGUEROLA, ALEXANDER STEPHAN
• Application Number:
  US09/596,846
• Time in Patent Office: 778 Days
• Field of Search: 204/403, 204/409, 204/416, 204/418, 204/419, 204/403.03
• US Class Current: 204/403.03
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 33/4875 Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method test-elements per se B01L, automatic analysers G01N35/00, in-vivo analysis on the human body for medical diagnosis A61B

Abstract

A biosensor is provided in accordance with this invention. The biosensor includes a bottom section with an edge and a flange extending from the edge, a top section supported on the bottom section and having an edge and flange extending from the edge in alignment with the flange of the bottom section. The flanges of the top and bottom sections cooperate to form a capillary channel, and first and second electrodes. Additionally, the first electrode is positioned on the flange of the bottom section in the capillary channel and the second electrode is positioned on the flange of the top section in the capillary channel.

Claims

1. A biosensor comprising:

a bottom section including an edge and a flange extending from the edge;

a spacer positioned on the bottom section spaced-apart from the flange of the bottom section;

a top section supported on the bottom section by the spacer, the top section including an edge and a flange extending from the edge of the top section in alignment with the flange of the bottom section, the flanges of the top and bottom sections cooperating to form a capillary channel;

a first electrode positioned on the flange of the bottom section in the capillary channel; and

a second electrode positioned on the flange of the top section in the capillary channel.

2. The biosensor of claim 1, further comprising a reagent positioned on at least one of the first and second electrodes.

3. The biosensor of claim 1, wherein the top and bottom sections are ring-shaped and have spaced-apart inner and outer edges.

4. The biosensor of claim 3, wherein each flange extends from the respective outer edges of the top and bottom sections.

5. The biosensor of claim 3, wherein the top and bottom sections each include a plurality of flanges extending from the respective outer edges.

6. The biosensor of claim 5, wherein the second electrode extends from the flange of the top section to the inner edge of the top section.

7. The biosensor of claim 3, wherein the first electrode extends from the flange of the bottom section to the inner edge of the bottom section.

8. The biosensor of claim 1, wherein the bottom section includes inner and outer edges and teeth adjacent to the inner edge.

9. The biosensor of claim 8, wherein the bottom section includes inner and outer surfaces and the teeth are positioned on the outer surface.

10. The biosensor of claim 1, wherein the top and bottom sections include a plurality of flanges.

11. The biosensor of claim 1, wherein the first electrode includes spaced-apart tracks.

12. The biosensor of claims 11, wherein the second electrode includes spaced-apart tracks.

22. The biosensor of claim 10, wherein the second electrode includes spaced-apart tracks.

13. A biosensor comprising:

a bottom section including an edge and a flange extending from the edge;

a top section supported on the bottom section, the top section including an edge and a flange extending from the edge of the top section in alignment with the flange of the bottom section, the flanges of the top and bottom sections cooperating to form a capillary channel;

a first electrode positioned on the flange of the bottom section in the capillary channel; and

a second electrode positioned on the flange of the top section in the capillary channel, wherein the top and bottom sections are ring-shaped and have spaced-apart inner and outer edges.

14. The biosensor of claim 13, wherein each flange extends from the respective outer edges of the top and bottom sections.

15. The biosensor of claim 13, wherein the top and bottom sections each include a plurality of flanges extending from the respective outer edges.

16. The biosensor of claim 15, wherein the second electrode extends from the flange of the top section to the inner edge of the top section.

17. The biosensor of claim 13, wherein the first electrode extends from the flange of the bottom section to the inner edge of the bottom section.

24. The biosensor of claim 13, further comprising a reagent positioned between the first and second electrodes.

18. A biosensor comprising:

a bottom section including an edge, a flange extending from the edge;

a top section supported on the bottom section, the top section including an edge and a flange extending from the edge of the top section in alignment with the flange of the bottom section, the flanges of the top and bottom sections cooperating to form a capillary channel,

a first electrode positioned on the flange of the bottom section in the capillary channel; and

a second electrode positioned on the flange of the top section in the capillary channel, wherein the bottom section includes inner and outer edges and teeth adjacent to the inner edge.

19. The biosensor of claim 18, wherein the bottom section includes inner and outer surfaces and the teeth are positioned on the outer surface.

20. A biosensor comprising:

a bottom section including an edge and a flange extending from the edge;

a top section supported on the bottom section, the top section including an edge and a flange extending from the edge of the top section in alignment with the flange of the bottom section, the flanges of the top and bottom sections cooperating to form a capillary channel;

a first electrode positioned on the flange of the bottom section in the capillary channel; and

a second electrode positioned on the flange of the top section in the capillary channel, wherein the top and bottom sections include a plurality of flanges.

21. A biosensor comprising:

a bottom section including an edge and a flange extending from the edge;

a top section supported on the bottom section, the top section including an edge and a flange extending from the edge of the top section in alignment with the flange of the bottom section, the flanges of the top and bottom sections cooperating to form a capillary channel;

a first electrode positioned on the flange of the bottom section in the capillary channel, the first electrode [includes] including spaced-apart tracks; and

a second electrode positioned on the flange of the top section in the capillary channel.

23. A biosensor comprising:

a first electrode including a base and a perimeter extending about the base,

a spacer situated on the base of the first electrode spaced-apart from the perimeter, and

a second electrode including a base situated on the spacer and a perimeter, the perimeters of the first and second electrodes cooperating to define a cantilevered capillary channel.

25. The biosensor of claim 23, wherein the bases of the first and second electrodes are each ring-shaped.

26. The biosensor of claim 23, wherein the base of the first electrode is formed to include spaced-apart tracks.

27. The biosensor of claim 26, wherein the base of the second electrode is formed to include spaced-apart tracks.

28. A biosensor comprising:

a first electrode including a base and a perimeter,

a spacer situated on the base of the first electrode,

a second electrode including a base situated on the spacer and a perimeter, the perimeters of the first and second electrodes cooperating to define a cantilevered capillary channel and the base of the first electrode is formed to include spaced-apart tracks.

29. The biosensor of claim 28, wherein the base of the second electrode is formed to include spaced-apart tracks.

30. A biosensor comprising:

a bottom section,

a first electrode positioned on the bottom section and including a base and a perimeter extending about the base,

a spacer positioned adjacent to the base of the first electrode, and

a second electrode including a base positioned adjacent to the spacer and a perimeter, the perimeters of the first and second electrodes cooperating to define a capillary channel spaced-apart from the spacer.

31. The biosensor of claim 30, wherein the bases of the first and second electrodes each include spaced-apart tracks in alignment with one another.

32. The biosensor of claim 31, wherein the spacer is positioned to lie between the tracks of the first and second electrodes.

33. DOW A biosensor comprising:

a bottom section,

a first electrode positioned on the bottom section and including a base and a perimeter,

a spacer positioned adjacent to the base of the first electrode, and

a second electrode including a base positioned adjacent to the spacer and a perimeter, the perimeters of the first and second electrodes cooperating to define a capillary channel, wherein the bases of the first and second electrodes each include spaced-apart tracks in alignment with one another.

34. The biosensor of claim 33, wherein the spacer is positioned to lie between the tracks of the first and second electrodes.