Cardiac rhythm management system with atrial shock timing optimization
First Claim
1. A method including:
- (a) detecting an atrial tachyarrhythmia;
(b) stabilizing a ventricular heart rate;
(c) determining if potentially proarrhythmic conditions exist using V-V intervals between ventricular events, including;
comparing a most recent V-V interval to a first predetermined value;
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than a first predetermined value;
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is shorter than the first predetermined value and the most recent V-V interval exceeds or equals a preceding V-V interval less a second predetermined value;
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is shorter than a third predetermined value; and
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than the third predetermined value and the most recent V-V interval is shorter than the preceding V-V interval less the second predetermined value; and
(d) delivering cardioversion/defibrillation therapy to the atrium if step (c) indicates no potentially proarrhythmic conditions exist, otherwise withholding the delivery of cardioversion/defibrillation therapy to the atrium until no potentially proarrhythmic conditions exist.
1 Assignment
0 Petitions
Accused Products
Abstract
A cardiac rhythm management system includes atrial shock timing optimization. Because an atrial tachyarrhythmia, such as atrial fibrillation typically causes significant variability in the ventricular heart rate, resulting in potentially proarrhythmic conditions. The system avoids delivering atrial cardioversion/defibrillation therapy during potentially proarrhythmic conditions because doing so could result in dangerous ventricular arrhythmias. Using Ventricular Rate Regularization (“VRR”) techniques, the system actively stabilizes the ventricular heart rate to obtain less potentially proarrhythmic conditions for delivering the atrial tachyarrhythmia therapy. The intrinsic ventricular heart rate is stabilized at a variable VRR-indicated rate, computed using an infinite impulse response (IIR) filter, and based on the underlying intrinsic ventricular heart rate. The system withholds delivery of atrial cardioversion/defibrillation therapy until the intervals between ventricular beats (“V-V intervals”) meet certain criteria that decrease the chance that the atrial cardioversion/defibrillation therapy will induce a ventricular arrhythmia.
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Citations
39 Claims
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1. A method including:
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(a) detecting an atrial tachyarrhythmia;
(b) stabilizing a ventricular heart rate;
(c) determining if potentially proarrhythmic conditions exist using V-V intervals between ventricular events, including;
comparing a most recent V-V interval to a first predetermined value;
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than a first predetermined value;
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is shorter than the first predetermined value and the most recent V-V interval exceeds or equals a preceding V-V interval less a second predetermined value;
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is shorter than a third predetermined value; and
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than the third predetermined value and the most recent V-V interval is shorter than the preceding V-V interval less the second predetermined value; and
(d) delivering cardioversion/defibrillation therapy to the atrium if step (c) indicates no potentially proarrhythmic conditions exist, otherwise withholding the delivery of cardioversion/defibrillation therapy to the atrium until no potentially proarrhythmic conditions exist. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is equal to the third predetermined value; and
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is equal to the first predetermined value.
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3. The method of claim 1, in which in (c) the first predetermined value is approximately between 700 milliseconds and 1000 milliseconds.
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4. The method of claim 1, in which in (c) the first predetermined value is programmable.
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5. The method of claim 1, in which in (c) the first predetermined value is approximately equal to 800 milliseconds.
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6. The method of claim 1, in which in (c) the first predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat.
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7. The method of claim 1, in which in (c) the second predetermined value is approximately between 0 milliseconds and 200 milliseconds.
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8. The method of claim 1, in which in (c) the second predetermined value is programmable.
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9. The method of claim 1, in which in (c) the second predetermined value is approximately equal to 90 milliseconds.
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10. The method of claim 1, in which in (c) the second predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat.
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11. The method of claim 1, in which in (c) the third predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat.
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12. The method of claim 1, in which in (c) the third predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat.
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13. The method of claim 1, in which in (c) the third predetermined value is approximately between 350 milliseconds and 1000 milliseconds, and the third predetermined value is one of:
- (1) less than the first predetermined value, or (2) less than or equal to the first predetermined value.
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14. The method of claim 1, in which in (c) the third predetermined value is programmable.
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15. The method of claim 1, in which in (c) the third predetermined value is approximately equal to 500 milliseconds.
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16. The method of claim 1, in which stabilizing the ventricular heart rate includes:
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obtaining V-V intervals between ventricular beats;
computing a first indicated pacing interval using at least a most recent V-V interval duration and a previous value of the first indicated pacing interval; and
providing pacing therapy, using the first indicated pacing interval.
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17. The method of claim 1, in which stabilizing the ventricular rate is initiated by the detection of an atrial tachyarrhythmia in (a).
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18. The method of claim 1, in which stabilizing the ventricular rate is independent of whether an atrial tachyarrhythmia is detected in (a).
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19. The method of claim 1, in which (d) includes synchronizing the delivery of the atrial cardioversion/defibrillation therapy to a ventricular depolarization.
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20. The method of claim 1, in which stabilizing the ventricular rate is using both sensed and paced ventricular beats.
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21. A method including:
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obtaining V-V intervals between ventricular beats;
computing a first indicated pacing interval using at least a most recent V-V interval duration and a previous value of the first indicated pacing interval;
providing pacing therapy, based on the first indicated pacing interval;
detecting a tachyarrhythmia in an atrium; and
then delivering cardioversion/defibrillation therapy to the atrium after the providing pacing therapy and the detecting the tachyarrhythmia in the atrium. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28)
comparing a most recent V-V interval to a first predetermined value; and
deeming no potentially proarrhythmic conditions to exist if one of (1) the most recent V-V interval is longer than a first predetermined value, or (2) the most recent V-V interval is longer than or equal to the first predetermined value.
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24. The method of claim 23, in which determining if potentially proarrhythmic conditions exist includes:
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is shorter than the first predetermined value and the most recent V-V interval is not shorter than a previous V-V interval by more than a second predetermined value.
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25. The method of claim 24, in which determining if potentially proarrhythmic conditions exist includes:
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deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is one of (1) shorter than a third predetermined value, or (2) shorter than or equal to the third predetermined value; and
wherein the third predetermined value is shorter than the first predetermined value.
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26. The method of claim 24, in which the first indicated pacing interval (Tn) is computed according to Tn=a·
- w·
VVn+(1−
w)·
Tn−
1, if VVn is concluded by an intrinsic beat, otherwise computing Tn according to Tn=b·
w·
VVn+(1−
w)·
Tn−
1, if VVn is concluded by a paced beat, where a, b, and w are coefficients, VVn is a most recent V-V interval duration, and Tn−
1 is a previous value of the first indicated pacing interval.
- w·
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27. The method of claim 26, in which at least one of a, b, and w is a function of heart rate.
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28. The method of claim 26, in which a is approximately between 1.0 and 2.0, b is approximately between 1.0 and 3.0, and w is approximately between 0 and 1.0.
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29. A cardiac rhythm management system, including a cardiac rhythm management device that includes:
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an atrial heart signal sensing circuit;
a ventricular heart signal sensing circuit, sensing V-V intervals between ventricular depolarizations, including intrinsic V-V intervals associated with a corresponding underlying intrinsic ventricular heart rate;
a ventricular pacing therapy circuit;
an atrial cardioversion/defibrillation therapy circuit; and
a controller, communicatively coupled to the atrial heart signal sensing circuit, the ventricular heart signal sensing circuit, the ventricular pacing therapy circuit, and the atrial cardioversion/defibrillation therapy circuit, the controller including;
a ventricular rate stabilization module, including a variable indicated rate and a corresponding variable indicated pacing interval, and in which the ventricular rate stabilization module stabilizes a ventricular heart rate at the variable indicated rate based on the underlying intrinsic ventricular heart rate, and in which the indicated pacing interval uses at least a most recent V-V interval duration and a preceding value of the indicated pacing interval; and
an atrial cardioversion/defibrillation control module that (a) determines if potentially proarrhythmic conditions exist based on V-V intervals between ventricular events, and (b) delivers cardioversion/defibrillation therapy to the atrium if no potentially proarrhythmic conditions exist, and otherwise withholds the delivery of cardioversion/defibrillation therapy to the atrium. - View Dependent Claims (30, 31)
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32. A method including:
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(a) detecting an atrial tachyarrhythmia;
(b) stabilizing a ventricular heart rate at a variable indicated rate using an underlying intrinsic ventricular heart rate;
(c) determining if potentially proarrhythmic conditions exist using V-V intervals between ventricular events, including;
comparing a most recent V-V interval to a first predetermined value; and
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than the first predetermined value, and deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is longer than or equal to the first predetermined value, and in which the first predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat; and
(d) delivering cardioversion/defibrillation therapy to an atrium if step (c) indicates no potentially proarrhythmic conditions exist, otherwise withholding the delivery of cardioversion/defibrillation therapy to the atrium until no potentially proarrhythmic conditions exist.
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33. A method including:
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(a) detecting an atrial tachyarrhythmia;
(b) stabilizing a ventricular heart rate at a variable indicated rate based on an underlying intrinsic ventricular heart rate;
(c) determining if potentially proarrhythmic conditions exist based on V-V intervals between ventricular events, including;
comparing a most recent V-V interval to a first predetermined value; and
deeming no potentially proarrhythmic conditions to exist if the most recent V-V interval is one of (1) longer than the first predetermined value, or (2) longer than or equal to the first predetermined value;
deeming that no potentially proarrhythmic conditions exist if the most recent V-V interval is shorter than the first predetermined value and the most recent V-V interval is not shorter than a previous V-V interval by more than a second predetermined value; and
(d) delivering cardioversion/defibrillation therapy to an atrium if step (c) indicates no potentially proarrhythmic conditions exist, otherwise withholding the delivery of cardioversion/defibrillation therapy to the atrium until no potentially proarrhythmic conditions exist. - View Dependent Claims (34, 35, 36, 37, 38, 39)
deeming potentially proarrhythmic conditions to exist if the most recent V-V interval is one of (1) shorter than a third predetermined value, or (2) shorter than or equal to the third predetermined value.
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39. The method of claim 38, in which the third predetermined value is different when the most recent V-V interval is initiated by a sensed beat than when the most recent V-V interval is initiated by a paced beat.
Specification