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Apparatus and method for rapid ultrasonic disruption of cells or viruses

  • US 6,431,476 B1
  • Filed: 12/21/1999
  • Issued: 08/13/2002
  • Est. Priority Date: 12/21/1999
  • Status: Expired due to Term
First Claim
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1. An apparatus for disrupting cells or viruses, the apparatus comprising:

  • a) a container having a chamber for holding the cells or viruses, wherein the container includes at least one wall defining the chamber;

    b) an ultrasonic transducer for contacting an external surface of the wall and for transmitting ultrasonic energy into the chamber through the wall; and

    c) a support structure for holding the container and the transducer against each other such that the transducer contacts the external surface of the wall and for applying to the container or to the transducer a substantially constant force to press together the transducer and the wall.

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