Method for treatment of sleep apneas
First Claim
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1. A method for treatment of sleep apneas comprising administration of a therapeutically effective amount of a Formula I azapirone compound or a pharmaceutically effective acid addition salt thereof to a patient in need of such treatment;
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whereinZ is a member selected from the group consisting of
with the dotted and solid line representing either a single or a double chemical bond;
A being selected from the group consisting of O, CH2, CH2CH2 and CH═
CH;
R3 and R4 being independently selected from hydrogen and C1-4 alkyl or R3 and R4 can be taken together as a butanediyl or pentanediyl chain; and
R1 and R2 are either taken together as or R1 is hydrogen and R2 is
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Abstract
Certain azapirone compounds and their pharmaceutically acceptable salts are useful in the treatment of sleep apneas.
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Citations
13 Claims
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1. A method for treatment of sleep apneas comprising administration of a therapeutically effective amount of a Formula I azapirone compound or a pharmaceutically effective acid addition salt thereof to a patient in need of such treatment;
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wherein Z is a member selected from the group consisting of
with the dotted and solid line representing either a single or a double chemical bond;
A being selected from the group consisting of O, CH2, CH2CH2 and CH═
CH;
R3 and R4 being independently selected from hydrogen and C1-4 alkyl or R3 and R4 can be taken together as a butanediyl or pentanediyl chain; and
R1 and R2 are either taken together asor R1 is hydrogen and R2 is - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification