Methods and apparatus for determining the location of a shaft within a vessel

• US 6,434,847 B1
• Filed: 11/02/1999
• Issued: 08/20/2002
• Est. Priority Date: 11/02/1999
• Status: Expired due to Term

• Current Assignee: Agilent Technologies, Inc.
• Original Assignee: Varian Incorporated (Agilent Technologies, Inc.)
• Inventors: Fernando, C. J. Anthony, Haw, Michael F., Duckett, Gregory S.
• Primary Examiner(s): NOLAND, THOMAS
• Application Number:
  US09/432,704
• Time in Patent Office: 1,022 Days
• Field of Search: 335/20, 335/33, 738/659, 73/18.1, 73/17.9, 73/10.1, 73/18.8, 738/66, 702/150, 702/158, 702/87, 702/166, 702/94, 702/97, 356/615, 356/617, 356/625, 250/231.18, 250/252.1 A
• US Class Current: 33/520
• CPC Class Codes: B01F 27/805 wherein the stirrers or the receptacles are moved in order to bring them into operative position; Means for fixing the receptacle
• CPC Class Codes: B01F 35/20 Measuring; Control or regulation
• CPC Class Codes: G01B 21/18 for measuring depth
• CPC Class Codes: G01B 21/24 for testing alignment of axes
• CPC Class Codes: G01D 5/26 characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
• CPC Class Codes: G01N 13/00 Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects scanning-probe techniques or apparatus G01Q
• CPC Class Codes: G01N 2013/006 Dissolution of tablets or the like
• CPC Class Codes: G01N 33/15 Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Abstract

Apparatus and methods for measuring the amount by which the centerline of a shaft disposed in a vessel is offset from the central vertical axis of the vessel, and for measuring the height of such shaft above the inside bottom of the vessel. Apparatus includes a shaft centerline offset measurement device, a shaft height measurement device, and a control/display console. Each measurement device includes a transducer or optical encoder for sensing a displaced position of a biased plunger to which a code strip is mounted. The devices may be combined into a single shaft offset and height measurement device. Improved methods include calculating shaft offset based on a plurality of readings from the transducer, and applying trigonometric relationships. The apparatus and methods are particularly useful in the verification of paddle or basket shafts utilized in dissolution testing stations, so that the dissolution testing protocol complies with government agency guidelines.

Claims

1. An apparatus mountable to a shaft disposed within a vessel and adapted for measuring the magnitude by which the centerline of the shaft is offset from the central axis of the vessel, comprising:

(a) a housing comprising a coupling component for coupling the housing to the shaft;

(b) a plunger slidably mounted to the housing, the plunger having an outer section extending radially outwardly beyond a wall of the housing, and having means for biasing the plunger radially outwardly;

(c) a transducer operatively mounted to the housing and adapted to encode positions of the plunger and to produce an electrical signal proportional to a change in position resulting from displacement of the plunger; and

(d) means for transferring the signal away from the housing.

2. The apparatus according to claim 1 wherein the coupling component includes a longitudinal recess defined by a recess wall extending inwardly toward an interior of the housing from a rear face of the housing.

3. The apparatus according to claim 2 wherein the recess wall has a cylindrical profile.

4. The apparatus according to claim 2 wherein the longitudinal recess includes an upper section extending downwardly from a top face of the housing, the upper section having a width greater than a width of an adjacent section of the longitudinal recess, the apparatus further comprising means disposed in the upper section for removably securing the housing to the shaft.

5. The apparatus according to claim 4 wherein the removably securing means includes a clip extending outwardly from the recess wall within the upper section, the clip including a pair of resilient prongs.

6. The apparatus according to claim 5 wherein each prong has an inside surface, and the clip and inside surfaces of the prongs cooperatively define a cylindrical profile.

7. The apparatus according to claim 1 wherein the housing has a bottom face and a groove extending inwardly toward an interior of the housing from the bottom face.

8. The apparatus according to claim 1 wherein the plunger is slidably disposed within the housing and the outer section of the plunger extends radially outwardly through a hole in the wall of the housing.

9. The apparatus according to claim 1 further comprising a plate mounted to the plunger and including a plurality of equally spaced lines readable by the transducer, wherein the transducer is an optical encoder disposed within the housing and the number of lines read by the transducer corresponds to a magnitude of the change in position of the plunger.

10. The apparatus according to claim 1 wherein the signal transferring means includes an electrical conduit.

11. The apparatus according to claim 1 comprising a device for interpreting the signal, the device disposed remotely in relation to the housing and communicating with the signal transferring means.

12. The apparatus according to claim 11 wherein the signal interpreting device comprises a display component for displaying the interpreted signal in human-readable form.

13. An apparatus mountable to a shaft disposed within a vessel and adapted for measuring the magnitude by which the centerline of the shaft is offset from the central axis of the vessel, comprising:

(a) a housing comprising a rear face, a top face, a longitudinal recess, and a clip, the longitudinal recess defined by a recess wall extending inwardly toward an interior of the housing, the longitudinal recess comprising an upper section extending downwardly from the top face, the upper section having a width greater than a width of an adjacent section of the longitudinal recess, the clip extending outwardly from the recess wall within the upper section and comprising a pair of resilient prongs;

(b) a plunger slidably mounted to the housing, the plunger having an outer section biased to extend radially outwardly beyond a wall of the housing;

(c) a transducer operatively mounted to the housing and adapted to encode positions of the plunger and to produce an electrical signal proportional to a change in position resulting from displacement of the plunger; and

(d) means for transferring the signal away from the housing.

14. The apparatus according to claim 13 wherein each prong has an inside surface, and the clip and inside surfaces of the prongs cooperatively define a cylindrical profile.

15. The apparatus according to claim 13 wherein the housing has a bottom face and a groove extending inwardly toward an interior of the housing from the bottom face.

16. The apparatus according to claim 13 wherein the plunger is slidably disposed within the housing and the outer section of the plunger extends radially outwardly through a hole in the wall of the housing.

17. The apparatus according to claim 13 further comprising a plate mounted to the plunger and including a plurality of equally spaced lines readable by the transducer, wherein the transducer is an optical encoder disposed within the housing and the number of lines read by the transducer corresponds to a magnitude of the change in position of the plunger.

18. The apparatus according to claim 13 wherein the signal transferring means includes an electrical conduit.

19. The apparatus according to claim 13 comprising a device for interpreting the signal, the device disposed remotely in relation to the housing and communicating with the signal transferring means.

20. The apparatus according to claim 19 wherein the signal interpreting device comprises a display component for displaying the interpreted signal in human-readable form.

21. An apparatus mountable to a shaft disposed within a vessel and adapted for measuring the magnitude by which the centerline of the shaft is offset from the central axis of the vessel, comprising:

(a) a housing;

(b) a plunger slidably mounted to the housing, the plunger having an outer section biased to extend radially outwardly beyond a wall of the housing;

(c) a transducer operatively mounted to the housing and adapted to encode positions of the plunger and to produce an electrical signal proportional to a change in position resulting from displacement of the plunger;

(d) means for transferring the signal away from the housing; and

(e) a device for interpreting the signal, the device disposed remotely in relation to the housing and communicating with the signal transferring means.

22. The apparatus according to claim 21 wherein the housing includes a rear face and a longitudinal recess defined by a recess wall extending inwardly toward an interior of the housing from the rear face.

23. The apparatus according to claim 22 wherein the recess wall has a cylindrical profile.

24. The apparatus according to claim 22 wherein the longitudinal recess includes an upper section extending downwardly from a top face of the housing, the upper section having a width greater than a width of an adjacent section of the longitudinal recess, the apparatus further comprising means disposed in the upper section for removably securing the housing to the shaft.

25. The apparatus according to claim 24 wherein the removably securing means includes a clip extending outwardly from the recess wall within the upper section, the clip including a pair of resilient prongs.

26. The apparatus according to claim 25 wherein each prong has an inside surface, and the clip and inside surfaces of the prongs cooperatively define a cylindrical profile.

27. The apparatus according to claim 21 wherein the housing has a bottom face and a groove extending inwardly toward an interior of the housing from the bottom face.

28. The apparatus according to claim 21 wherein the plunger is slidably disposed within the housing and the outer section of the plunger extends radially outwardly through a hole in the wall of the housing.

29. The apparatus according to claim 21 further comprising a plate mounted to the plunger and including a plurality of equally spaced lines readable by the transducer, wherein the transducer is an optical encoder disposed within the housing and the number of lines read by the transducer corresponds to a magnitude of the change in position of the plunger.

30. The apparatus according to claim 21 wherein the signal transferring means includes an electrical conduit.

31. The apparatus according to claim 30 wherein the signal interpreting device comprises a display component for displaying the interpreted signal in human-readable form.