Aerosol medication delivery apparatus and system

• US 6,435,177 B1
• Filed: 08/15/2001
• Issued: 08/20/2002
• Est. Priority Date: 09/26/1997
• Status: Expired due to Term

• Current Assignee: Trudell Medical International (Trudell Medical Limited)
• Original Assignee: Trudell Medical International (Trudell Medical Limited)
• Inventors: Morton, Robert, Foley, Martin P., Engelbreth, Daniel K., Grychowski, Jerry, Schmidt, James N.
• Primary Examiner(s): Weiss, John G.
• Assistant Examiner(s): MITCHELL, TEENA KAY
• Application Number:
  US09/929,947
• Publication Number:
  US 20020026935A1
• Time in Patent Office: 370 Days
• Field of Search: 128/200.11, 128/200.12, 128/200.14, 128/200.18, 128/200.23, 128/200.24, 128/203.21, 128/203.18, 128/203.23, 128/205.24
• US Class Current: 128/200.23
• CPC Class Codes: A61M 11/002 by flow deviation causing inertial separation of transported particles
• CPC Class Codes: A61M 11/003 by passing the aerosol trough sieves or filters
• CPC Class Codes: A61M 15/0016 located downstream of the dispenser, i.e. traversed by the product
• CPC Class Codes: A61M 15/0086 Inhalation chambers
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0616 with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure

Abstract

The invention provides an aerosol medication delivery apparatus for use with a pMDI canister having medication and a propellant contained therein under pressure, wherein the pMDI canister has a discharge orifice from which the medication and propellant can be discharged forming an aerosol. The apparatus has a chamber housing having an input end and an output end and defining an interior space, wherein the input end receives the medication discharged from the discharge orifice of the pMDI canister into the interior space and wherein the medication can be withdrawn from the interior space by inhalation by a patient from the output end. The aerosol medication delivery apparatus also includes a valve at the output end. The valve has a valve seat and a valve member. The valve seat has a sealing surface and the valve member has a central open area and a sealing portion at the perimeter of the open area that mates with the sealing surface when the valve is closed. The valve allows medication to be withdrawn through the central open area but prevents backflow into the chamber housing.

Claims

1. An aerosol delivery apparatus comprising:

a chamber housing comprising an input end and an output end and defining a longitudinal axis, said output end comprising a valve seat; and

a valve member comprising an inner portion having a center opening, an outer portion formed along at least a portion of an outer perimeter of said valve member, and a longitudinally extending portion disposed between said inner and outer portions, wherein said longitudinally extending portion engages said output end and locates said valve member on said output end, and wherein said outer portion mates with said valve seat and is moveable away from said valve seat.

2. The invention of claim 1 wherein said valve seat comprises a first valve seat and said output end further comprising a second valve seat, and wherein said inner portion of said valve mates with said second valve seat and is moveable away from said second valve seat.

3. The invention of claim 2 wherein said outer portion has a curved surface facing said input end of said chamber housing.

4. The invention of claim 2 wherein said outer portion is moveable away from said first valve seat in a first direction and wherein said inner portion is moveable away from said second valve seat in a second direction opposite said first direction.

5. The invention of claim 1 further comprising a baffle member located at said output end.

6. The invention of claim 5 wherein said baffle member has a curved surface facing said input end of said chamber housing.

7. The invention of claim 1 wherein said longitudinally extending portion comprises a wall extending between said inner and outer portions.

8. The invention of claim 7 wherein said wall is annular and surrounds said central opening.

9. The invention of claim 1 wherein said chamber housing comprises a main housing and a downstream portion defining a mouthpiece, wherein said valve member is disposed between said main housing and said downstream portion.

10. The invention of claim 9 wherein said downstream portion comprises a plurality of retaining ribs, wherein said valve member is disposed between an end of said main housing and said retaining ribs.

11. The invention of claim 9 wherein said valve seat is formed on said downstream portion.

12. The invention of claim 1 wherein said center opening is substantially circular.

13. The invention of claim 1 wherein said longitudinally extending portion and said inner portion form a recess, wherein a portion of said output end is received in said recess.

14. The invention of claim 1 wherein said longitudinally extending portion surrounds said central opening.

15. An aerosol delivery apparatus comprising:

a chamber housing having an input end and an output end, wherein said output end comprises a first valve seat and a second valve seat; and

a valve member having a center opening, an inner sealing portion formed around a perimeter of said center opening and an outer sealing portion formed radially outward from said inner sealing portion, wherein at least a portion of said inner sealing portion comprises a curved surface facing toward said input end of said chamber housing, wherein said inner sealing portion mates with said second valve seat and wherein said outer sealing portion mates with said first valve seat.

16. The invention of claim 15 wherein said curved surface facing toward said input end is convex.

17. The invention of claim 16 wherein said at least said portion of said inner sealing portion further comprises a concave surface facing away from said input end.

18. The invention of claim 15 wherein said at least said portion of said inner sealing portion is dome shaped.

19. The invention of claim 15 wherein said valve member comprises a middle portion connecting said inner sealing portion and said outer sealing portion, and wherein said middle portion mates with said output end and is substantially non-moveable relative thereto.

20. The invention of claim 19 wherein said middle portion comprises a wall engaging said output end.

21. The invention of claim 20 wherein said outer sealing portion extends radially from said middle portion.

22. The invention of claim 15 wherein said chamber housing comprises a main housing and a downstream portion defining a mouthpiece, wherein said valve member is disposed between said main housing and said downstream portion.

23. The invention of claim 22 wherein said downstream portion comprises a plurality of retaining ribs, wherein said valve member is disposed between an end of said main housing and said retaining ribs.

24. The invention of claim 22 wherein said first valve seat is formed on said downstream portion.

25. The invention of claim 15 wherein said center opening is substantially circular.

26. The invention of claim 15 further comprising a baffle member located at said output end and defining said second valve seat.

27. The invention of claim 26 wherein said baffle member has a curved surface facing said input end of said chamber housing.

28. A method for administering an aerosol comprising:

providing a delivery apparatus comprising;

a chamber housing comprising an input end and an output end and defining a longitudinal axis, said output end comprising a valve seat; and

a valve member comprising an inner portion having a center opening, an outer sealing portion formed along at least a portion of an outer perimeter of said valve member, and a longitudinally extending portion disposed between said inner and outer portions, wherein said longitudinally extending portion engages said output end and locates said valve member on said output end, and wherein said outer portion is moveably seated on said valve seat and is moveable away from said valve seat;

introducing an aerosol into said input end of said chamber housing;

inhaling said aerosol through said output end and through said center opening;

seating said outer portion on said valve seat during said inhaling of said aerosol; and

exhaling and thereby moving at least a portion of said outer portion away from said valve seat.

29. The invention of claim 28 wherein said valve seat comprises a first valve seat and said output end further comprising a second valve seat, and wherein said inner portion of said valve is moveably seated on said second valve seat and is moveable away from said second valve seat, and wherein said inhaling said aerosol further comprises moving at least a portion of said inner portion away from said second valve seat, and further comprising seating said inner portion on said second valve seat during said exhaling.

30. The invention of claim 29 wherein said outer portion is moveable away from said first valve seat in a first direction and wherein said inner portion is moveable away from said second valve seat in a second direction opposite said first direction.

31. The invention of claim 28 wherein said longitudinally extending portion comprises a wall.

32. The invention of claim 28 further comprising a baffle member located at said output end.

33. The invention of claim 32 wherein said baffle member has a curved surface facing said input end of said chamber housing.

34. The invention of claim 28 wherein said inner portion has a curved surface facing said input end of said chamber housing.

35. The invention of claim 34 wherein said curved surface is convex.

36. The invention of claim 28 wherein said chamber housing comprises a main housing and a downstream portion defining a mouthpiece, wherein said valve member is disposed between said main housing and said downstream portion and wherein said inhaling and said exhaling comprises inhaling and exhaling through said mouthpiece.

37. The invention of claim 36 wherein said downstream portion comprises a plurality of retaining ribs, wherein said valve member is disposed between an end of said main housing and said retaining ribs.

38. The invention of claim 36 wherein said second valve seat is formed on said downstream portion.

39. The invention of claim 28 wherein said center open area is substantially circular.

40. The invention of claim 28 wherein said longitudinally extending portion surrounds said central opening.

41. An aerosol delivery apparatus comprising:

a chamber housing having an input end and an output end, wherein said output end comprises a first valve seat and a second valve seat; and

a valve member having a central open area and comprising a first sealing portion formed continuously around a perimeter of said central open area and a second sealing portion formed along at least a portion of an outer perimeter of said valve member, wherein said first sealing portion mates with said first valve seat and wherein an entirety of said first sealing portion formed continuously around said perimeter of said central opening is moveable away from said first valve seat in a first direction from a first position to a second position, and wherein said second sealing portion mates with said second valve seat and is moveable away from said second valve seat in a second direction opposite said first direction.

42. An aerosol delivery apparatus comprising:

a chamber housing having a longitudinal axis, an input end and an output end longitudinally spaced from said input end, wherein said output end comprises a first valve seat and a second valve seat; and

a valve member having a central open area and comprising a first sealing portion formed along at least a portion of a perimeter of said central open area, a second sealing portion formed along at least a portion of an outer perimeter of said valve member, and a middle portion connecting said first and second sealing portions, wherein said first sealing portion is longitudinally spaced from said second sealing portion, wherein said first sealing portion mates with said first valve seat and is moveable away from said first valve seat, and wherein said second sealing portion mates with said second valve seat and is moveable away from said second valve seat.

43. The invention of claim 42 wherein at least a portion of said first and second sealing portions are substantially parallel.

44. A method for administering an aerosol comprising:

providing a delivery apparatus comprising;

a chamber housing having an input end and an output end, wherein said output end comprises a first valve seat and a second valve seat; and

a valve member having a center opening, an inner portion formed around a perimeter of said center opening and an outer portion formed radially outward from said inner sealing portion, wherein at least a portion of said inner portion comprises a curved member having a curved surface facing said input end of said chamber housing, wherein said inner portion mates with said first valve seat and wherein said outer portion mates with said second valve seat;

introducing an aerosol into said input end of said chamber housing;

inhaling said aerosol through said output end and through said center opening and thereby moving at least a portion of said inner portion away from said second valve seat;

seating said outer portion on said second valve seat during said inhaling of said aerosol; and

exhaling and thereby moving at least a portion of said outer portion away from said first valve seat.

45. The invention of claim 44 further comprising seating said inner portion on said second valve seat after said inhaling of said aerosol.

46. An aerosol delivery apparatus comprising:

a chamber housing comprising an input end and an output end, said output end comprising a valve seat; and

a valve member comprising an inner portion having a circular center opening and an outer portion formed along at least a portion of an outer perimeter of said valve member, wherein said outer portion mates with said valve seat and is moveable away from said valve seat.

47. An aerosol delivery apparatus comprising:

a chamber housing comprising an input end and an output end, said output end comprising a valve seat; and

an annular shaped valve member comprising an inner perimeter defining a central open area and comprising an outer portion formed along at least a portion of an outer perimeter of said valve member, wherein said outer portion mates with said valve seat and is moveable away from said valve seat.