Intravascular systems for corporeal cooling

• US 6,436,071 B1
• Filed: 06/08/1999
• Issued: 08/20/2002
• Est. Priority Date: 06/08/1999
• Status: Expired due to Fees

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Schwartz, Arthur E.
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): RAM, JOCELYN D
• Application Number:
  US09/330,428
• Time in Patent Office: 1,169 Days
• Field of Search: 604/113, 604/102.01, 604/102.02, 604/102.03, 604/247
• US Class Current: 604/113
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1059 having different inflatable sections mainly depending on the response to the inflation pressure, e.g. due to different material properties
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 25/0662 Guide tubes
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

A catheter for intravascular corporeal cooling comprises an elongated tubular member having at least one lumen extending therethrough for providing cooled blood, an inflatable annular balloon positioned on the outer surface of the elongated tubular member, and a pressure reliever positioned in the external wall of the elongated tubular member and proximal to the annular inflatable balloon, wherein when the pressure of blood within a lumen reaches a predetermined value, the pressure reliever opens to permit fluid to be released from the elongated tubular member. In other embodiments of the invention the catheter may have two or more inflatable annular balloons that are separately inflatable and/or the catheter has an insulative outer annular member.

Claims

1. A catheter for intravascular corporeal cooling which comprises:

an elongated tubular member having proximal and distal sections, at least first and second lumens extending therethrough, an outer surface, and an outer wall,

an inflatable annular balloon positioned on the outer surface of the elongated tubular member and in fluid communication with a lumen for inflation, and

pressure relief means positioned in the outer wall of the elongated tubular member and proximal to the annular inflatable balloon,

wherein at least the first lumen can provide cooled blood in the distal direction and distal to the inflatable annular balloon, and when the pressure of fluid within the first lumen reaches a predetermined value, the pressure relief means opens to permit fluid to be released from the elongated tubular member.

2. The catheter of claim 1, wherein the annular balloon is in fluid communication with an inflation lumen extending longitudinally through the tubular member.

3. The catheter of claim 1, which comprises at least one additional inflatable annular balloon.

4. The catheter of claim 3, wherein each inflatable annular balloon is in fluid communication with an inflation lumen.

5. The catheter of claim 1 which also comprises a pressure sensor at or adjacent to the distal end of the catheter.

6. The catheter of claim 1 which has been adapted for brain cooling.

7. The catheter of claim 1, wherein at least one lumen is in fluid communication with a source of cooled blood.

8. The catheter of claim 1, wherein at least one lumen is in fluid communication with a liquid pharmaceutical source.

9. A catheter for intravascular corporeal cooling which comprises:

an elongated tubular member having proximal and distal sections, at least first and second lumens extending therethrough, an outer surface, and an outer wall;

an inflatable annular balloon positioned on the outer surface of the elongated tubular member and in fluid communication wit a lumen for inflation; and

pressure relief means comprising a one-way valve positioned in the outer wall of the elongated tubular member and proximal to the annular inflatable balloon,

wherein at least the first lumen can provide cooled blood in the distal direction and distal to the inflatable annular balloon, and wherein when the pressure of fluid within the first lumen reaches a predetermined value, the pressure relief means opens to permit fluid to be released from the elongated tubular member.

10. The catheter of claim 9, wherein the annular balloon is in fluid communication with an inflation lumen extending longitudinally through the elongated tubular member.

11. The catheter of claim 9, which comprises at least one additional inflatable annular balloon.

12. The catheter of claim 11, wherein each inflatable annular balloon is in fluid communication with an inflation lumen.

13. The catheter of claim 9 which also comprises a pressure sensor at or adjacent to the distal end of the elongated tubular member.

14. The catheter of claim 9 which is useful for brain cooling.

15. The catheter of claim 9, wherein at least one lumen is in fluid communication with a source of cooled blood.

16. The catheter of claim 9, wherein at least one lumen is in fluid communication with a liquid pharmaceutical source.

17. A catheter for intravascular corporeal cooling which comprises:

an elongated tubular member having proximal and distal sections, at least first and second lumens extending therethrough, an outer surface, and an outer wall;

an inflatable annular balloon positioned on the outer surface of the elongated tubular member and in fluid communication with a lumen for inflation;

pressure relief means positioned in the outer wall of the elongated tubular member and proximal to the annular inflatable balloon, and

a pressure sensor at or adjacent to the distal end of the elongated tubular member,

wherein at least the first lumen can provide cooled blood in the distal direction and distal to the inflatable annular balloon, and wherein when the pressure relief means opens to permit to be released from the elongated tubular member.

18. The catheter of claim 17, wherein the pressure relief means comprises an elongated fissure.

19. The catheter of claim 17, wherein the annular balloon is in fluid communication with an inflation lumen extending longitudinally through the elongated tubular member.

20. The catheter of claim 17, which comprises at least one additional inflatable annular balloon.

21. The catheter of claim 20, wherein each inflatable annular balloon is in fluid communication with an inflation lumen.

22. The catheter of claim 17 which is useful for brain cooling.

23. The catheter of claim 17, wherein at least one lumen is in fluid communication with a source of cooled blood.

24. The catheter of claim 17, wherein at least one lumen is in fluid communication with a liquid pharmaceutical source.

25. A catheter for intravascular corporeal cooling which comprises:

an elongated tubular member having proximal and distal sections, at least first and second lumens extending therethough, an outer surface, and an outer wall;

an inflatable annular balloon positioned on the outer surface of the elongated tubular member and in fluid communication with a lumen for inflation; and

pressure relief positioned in the outer wall of the elongated tubular member and proximal to the annular inflatable balloon,

wherein at least the first lumen can provide cooled blood in the distal direction and distal to the inflatable annular balloon, wherein at least one lumen is in fluid communication with a source of cooled blood, and wherein when the pressure of fluid within the first lumen reaches a predetermined value, the pressure relief means opens to permit fluid to be released from the elongated tubular member.

26. The catheter of claim 25, wherein the pressure relief means comprises an elongated fissure.

27. The catheter of claim 25, wherein the annular balloon is in fluid communication with an inflation lumen extending longitudinally through the elongated tubular member.

28. The catheter of claim 25, which comprises at least one additional inflatable annular balloon.

29. The catheter of claim 28, wherein each inflatable annular balloon is in fluid communication with an inflation lumen.

30. The catheter of claim 25 which is useful for brain cooling.

31. The catheter of claim 25, wherein at least one lumen is in fluid communication with a liquid pharmaceutical source.

32. A catheter for intravascular coporeal cooling which comprises:

an elongated tubular member having proximal and distal sections, at least first and second lumens extending therethrough, an outer surface, and an outer wall;

an inflatable annular balloon positioned on the outer surface of the elongated tubular member and in fluid communication with a lumen for inflation; and

pressure relief means positioned in the outer wall of the elongated tubular member and proximal to the annular inflatable balloon,

wherein at least the first lumen can provide cooled blood in the distal direction and distal to the inflatable annular balloon, wherein at least one lumen is in fluid communication with a liquid pharmaceutical source, and wherein when the pressure of fluid within the first lumen reaches a predetermined value, the pressure relief means opens to permit fluid to be released from the elongated tubular member.

33. The catheter of claim 32, wherein the pressure relief means comprises an elongated fissure.

34. The catheter of claim 32, wherein the annular balloon is in fluid communication with an inflation lumen extending longitudinally through the elongated tubular member.

35. The catheter of claim 32, which comprises at least one additional inflatable annular balloon.

36. The catheter of claim 35, wherein each inflatable annular balloon is in fluid communication with an inflation lumen.

37. The catheter of claim 32 which is useful for brain cooling.