Composite intraluminal prostheses

• US 6,436,132 B1
• Filed: 03/30/2000
• Issued: 08/20/2002
• Est. Priority Date: 03/30/2000
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Stack, Richard S., Patel, Udayan G.
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US09/539,258
• Time in Patent Office: 873 Days
• Field of Search: 623/1.15, 623/1.13, 623/1.11, 623/1.16, 623/1.18, 606/191, 606/195, 606/198
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching

Abstract

A composite intraluminal prostheses for treating a stenotic region in a blood vessel. The intraluminal prostheses including a thermally expandable stent and an open cell stent cover where the cell size is selected to be small enough to prevent plaque prolapse and the ingrowth of diseased tissue through the openings in the stent, while allowing for the re-endothelialization of the blood vessel wall with healthy tissue. The stent cover is further able to expand and contract with the stent without becoming loose upon contraction and without exerting significant resistence to radial expansion.

Claims

1. A thermally expandable intraluminal prostheses for implanting in a body lumen comprising an expandable stent body, the stent body having a first configuration having a first diameter at temperature T2 and having a second configuration having a second diameter at temperature T1, wherein the second diameter is smaller than the first diameter and temperature T1 is lower than temperature T2;

and

an expandable polymer open cell mesh cover coupled with the expandable stent body, wherein the polymer mesh cover exhibits minimal resistence to radial expansion and has a multiplicity of cell openings greater than 100 microns in width.

2. The intraluminal prostheses of claim 1, wherein the stent body includes a plurality of spaced apart coaxially aligned rings, each ring comprising a plurality of oval elements having straight sides and semicircular ends;

the oval elements being connected adjacent to each other along the straight sides, wherein each oval element is angularly displaced from the next at a constant radius; and

a plurality of connecting elements for interconnecting the spaced apart rings, wherein the connecting elements connect the semicircular ends of the oval elements which form the rings.

3. The intraluminal prostheses of claim 2, wherein the oval elements have an aspect ratio of 2:

1.

4. The intraluminal prostheses of claim 2, wherein the oval elements have an overall length of 2 mm and the semicircular ends of a radius of 0.5 mm.

5. The intraluminal prostheses of claim 2, wherein the connecting links have a length of 1 mm.

6. The intraluminal prostheses of claim 2, wherein the expandable polymer mesh cover has square shaped cells.

7. The intraluminal prostheses of claim 6, wherein the square shaped cells are 1 mm square.

8. The intraluminal prostheses of claim 2, wherein the expandable polymer mesh cover has diamond shaped cells.

9. The intraluminal prostheses of claim 2, wherein the expandable polymer mesh cover is made from expanded polytetrafluorothylene.

10. The intraluminal prostheses of claim 2, wherein the expandable polymer mesh cover is made is bonded to each cell of the stent body.

11. The intraluminal prostheses of claim 2, wherein the proximal and distal edges of the expandable polymer mesh cover are bonded to the proximal and distal edges of the stent body.

12. The intraluminal prostheses of claim 1, wherein the stent body includes a plurality of adjacent coaxially aligned rings, each ring comprising a plurality of oval elements having straight sides and semicircular ends;

the oval elements being connected adjacent to each other along the straight sides, wherein each oval element is angularly displaced from the next at a constant radius; and

each ring of oval elements being connected to the oval elements in adjacent rings at the semicircular ends.

13. The intraluminal prostheses of claim 12, wherein the oval elements have an aspect ratio of 2:

1.

14. The intraluminal prostheses of claim 12, wherein the oval elements have an overall length of 2 mm and the semicircular ends of a radius of 0.5 mm.

15. The intraluminal prostheses of claim 12, wherein the expandable polymer mesh cover has square shaped cells.

16. The intraluminal prostheses of claim 15, wherein the square shaped cells are 1 mm square.

17. The intraluminal prostheses of claim 12, wherein the expandable polymer mesh cover has diamond shaped cells.

18. The intraluminal prostheses of claim 12, wherein the expandable polymer mesh cover is made from expanded polytetrafluorothylene.

19. The intraluminal prostheses of claim 12, wherein the expandable polymer mesh cover is made is bonded to each cell of the stent body.

20. The intraluminal prostheses of claim 12, wherein the proximal and distal edges of the expandable polymer mesh cover are bonded to the proximal and distal edges of the stent body.

21. The intraluminal prostheses of claim 1, wherein the stent body is made from a shape memory material.

22. The intraluminal prostheses of claim 1, wherein the stent body is made from a material selected from the group consisting of NiTi binary alloys, Ni—

Ti—

X (X being V, Co, Cu, Fe) ternary alloys, Cu—

Al—

Ni ternary alloys, and Cu—

Zn—

Al ternary alloys.

23. The intraluminal prostheses of claim 1, wherein the stent body is made from nitinol.

24. The intraluminal prostheses of claim 1, wherein the expandable polymer mesh cover has square shaped cells.

25. The intraluminal prostheses of claim 24, wherein the square shaped cells are 1 mm square.

26. The intraluminal prostheses of claim 1, wherein the expandable polymer mesh cover has diamond shaped cells.

27. The intraluminal prostheses of claim 1, wherein the expandable polymer mesh cover is made from expanded polytetrafluorothylene.

28. The intraluminal prostheses of claim 1, wherein the expandable polymer mesh cover is made is bonded to each cell of the stent body.

29. The intraluminal prostheses of claim 1, wherein the proximal and distal edges of the expandable polymer mesh cover are bonded to the proximal and distal edges of the stent body.

30. The intraluminal prostheses of claim 1, wherein the expanded polymer open cell mesh cover is made from braided filaments of expanded polytetrafluoroethylene.

31. The intraluminal prostheses of claim 30, wherein the expandable polymer open cell mesh cover is applied to the stent body by thermoplastic adhesive.

32. The intraluminal prostheses of claim 1, wherein the multiplicity of cell openings are greater than about 0.2 mm in width.

33. The intraluminal prostheses of claim 1, wherein the multiplicity of cell openings are between about 0.2 mm to about 1.5 mm in width.