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Process and device for measuring tear fluorescein clearance

  • US 6,438,398 B1
  • Filed: 03/03/2000
  • Issued: 08/20/2002
  • Est. Priority Date: 03/05/1999
  • Status: Expired due to Fees
First Claim
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1. A process of measuring tear clearance from a mammalian eye, comprising:

  • (a) instilling an effective amount of fluorescein dye solution into an inferior conjunctival sac of an eye;

    (b) incubating the fluorescein dye solution in the conjunctival sac for a period of time sufficient to allow dye to mix with tear fluid;

    (c) collecting a sample of the tear fluid from the eye;

    (d) determining the volume of the tear fluid collected; and

    (e) measuring an amount of fluorescence present in the tear fluid by comparison with a color standard.

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