Local cardiac motion control using applied electrical signals

• US 6,442,424 B1
• Filed: 05/26/1999
• Issued: 08/27/2002
• Est. Priority Date: 05/26/1999
• Status: Expired due to Term

• Current Assignee: Impulse Dynamics NV
• Original Assignee: Impulse Dynamics NV
• Inventors: Mika, Yuval, Malonek, Dov, Rousso, Benny, Ben-Haim, Shlomo, Darvish, Nissim, Felzen, Bella
• Primary Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US09/320,090
• Time in Patent Office: 1,189 Days
• Field of Search: 607/4, 607/5, 607/14, 607/15, 607/66, 607/2, 607/3, 607/9
• US Class Current: 607/3
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A method and apparatus for performing a medical procedure on a beating heart. Electrical signals are applied to the heart so as to reduce motion of a segment thereof, and the procedure is performed while the heart continues to pump blood. Preferably, the motion increases spontaneously after the signals are removed.

Claims

1. A method for performing a medical procedure on a beating heart, comprising:

applying electrical signals to the heart so as to reduce motion of a segment thereof;

performing the procedure while the heart continues to pump blood; and

mechanically stabilizing the segment in conjunction with applying the electrical signals.

2. A method for performing a medical procedure on a beating heart, comprising:

applying electrical signals to the heart so as to reduce motion of a segment thereof; and

performing the procedure while the heart continues to pump blood,

wherein applying the electrical signals comprises calibrating the signals intermittently during the procedure.

3. A method for performing a medical procedure on a beating heart, comprising:

applying electrical signals to the heart so as to reduce motion of a segment thereof; and

performing the procedure while the heart continues to pump blood,

wherein applying the electrical signals comprises applying a first signal so as to precondition a response of the heart to a subsequent signal, which reduces the motion during the procedure.

4. A method for performing a medical procedure on a beating heart, comprising:

applying electrical signals to the heart so as to reduce motion of a segment thereof;

performing the procedure while the heart continues to pump blood; and

sensing motion of the heart,

wherein applying the signals comprises modifying a characteristic of at least some of the signals applied to the heart responsive to the sensed motion.

5. A method according to claim 4, wherein sensing the motion comprises coupling at least one motion sensor to detect motion of the segment of the heart, wherein modifying the characteristic comprises modifying a signal characteristic so as to reduce the motion of the segment.

6. A method for performing a medical procedure on a beating heart, comprising:

applying electrical signals to the heart so as to reduce motion of a segment thereof; and

performing the procedure while the heart continues to pump blood,

wherein applying the electrical signals comprises applying signals at a plurality of sites on the heart, and

wherein applying the signals comprises applying a first waveform at a first one of the sites and applying a second waveform, which differs from the first waveform, at a second one of the sites.

7. A method according to claim 6, wherein applying the first and second waveforms comprises controlling a timing relationship of the waveforms so as to reduce the motion of the segment.

8. Apparatus for performing a medical procedure on a beating heart, comprising:

one or more electrodes, coupled to the heart;

a control unit, which actuates the electrodes to apply electrical signals to the heart so as to substantially reduce motion of a segment thereof while the heart continues to pump blood, whereby the procedure is performed on the segment; and

one or more motion sensors, coupled to the heart and to the control unit, which sense motion of the heart,

wherein the control unit modifies the signals applied to the heart responsive to the motion.

9. Apparatus according to claim 8, wherein at least one of the one or more motion sensors is coupled to the segment of the heart, and wherein the control unit modifies the signals so as to minimize motion sensed by the at least one sensor.

10. Apparatus for performing a medical procedure on a beating heart, comprising:

one or more electrodes, coupled to the heart;

a control unit, which actuates the electrodes to apply electrical signals to the heart so as to substantially reduce motion of a segment thereof while the heart continues to pump blood, whereby the procedure is performed on the segment; and

one or more fencing electrodes, coupled to the heart, which are actuated by the control unit to apply a fencing signal to the heart so as to block propagation of an activation wave into the segment.

11. Apparatus for performing a medical procedure on a beating heart, comprising:

one or more electrodes, coupled to the heart; and

a control unit, which actuates the electrodes to apply electrical signals to the heart so as to substantially reduce motion of a segment thereof while the heart continues to pump blood, whereby the procedure is performed on the segment; and

one or more fencing electrodes, coupled to heart tissue in a vicinity of the segment, which are actuated by the control unit to apply a fencing signal to the segment so as to reduce a contraction force thereof.

12. Apparatus for performing a medical procedure on a beating heart, comprising:

one or more electrodes, coupled to the heart;

a control unit, which actuates the electrodes to apply electrical signals to the heart so as to substantially reduce motion of a segment thereof while the heart continues to pump blood, whereby the procedure is performed on the segment; and

a mechanical stabilizer, which is applied to the heart to restrain motion thereof, in conjunction with motion reduction using the one or more electrodes.

13. A method for performing a medical procedure on smooth muscle tissue having a tendency to motion, comprising:

applying electrical signals to the tissue so as to reduce motion of a segment thereof, such that the motion increases spontaneously upon removal of the signals; and

performing the procedure while the motion is reduced.

14. A method for performing a medical procedure on skeletal muscle tissue having a tendency to motion, comprising:

applying electrical signals to the tissue so as to reduce motion of a segment thereof, such that the motion increases spontaneously upon removal of the signals; and

performing the procedure while the motion is reduced.

15. A method for performing a medical procedure on muscle tissue having a tendency to motion, comprising:

applying electrical signals to the tissue so as to reduce motion of a segment thereof, such that the motion increases spontaneously upon removal of the signals; and

performing the procedure while the motion is reduced,

wherein performing the procedure comprises performing a diagnostic procedure.