Centrifugal blood pump apparatus

• US 6,443,983 B1
• Filed: 12/17/1999
• Issued: 09/03/2002
• Est. Priority Date: 05/13/1997
• Status: Expired due to Fees

• Current Assignee: Dan Lemay, Jack Sternlieb, Kurt H. Wieland, Lorant Nagyszalanczy, Norman E. Spicer
• Original Assignee: Dan Lemay, Jack Sternlieb, Kurt H. Wieland, Lorant Nagyszalanczy, Norman E. Spicer
• Inventors: Spicer, Norman E., Wieland, Kurt H., Nagyszalanczy, Lorant, Sternlieb, Jack, Lemay, Dan
• Primary Examiner(s): SNOW, BRUCE EDWARD
• Application Number:
  US09/466,309
• Time in Patent Office: 991 Days
• Field of Search: 623/3.1, 623/3.13, 623/3.28, 606/16, 606/17, 415/900
• US Class Current: 623/3.28
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/196 replacing the entire heart, e.g. total artificial hearts [TAH]
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/546 of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/554 of blood pressure
• CPC Class Codes: A61M 60/562 for making blood flow pulsatile in blood pumps that do not intrinsically create pulsatile flow
• CPC Class Codes: A61M 60/806 Vanes or blades
• CPC Class Codes: A61M 60/827 Sealings between moving parts
• CPC Class Codes: A61M 60/829 having a purge fluid supply
• CPC Class Codes: Y10S 415/90 Rotary blood pump

Abstract

A centrifugal impeller-type pump for transporting blood has a new and improved design in the impeller, to allow for the elimination of stagnant flow areas, and a geometrical design that minimizes damage to the blood components. A system for controlling and stabilizing the speed of centrifugal-type pumps used in a human cardiovascular system is also provided. Further provided are methods of corrosion protection and enhancing thromboresistance, rejection of waste heat, and methods to connect the artificial heart to the cardiovascular system as a Left Ventricle Assist Device (LVAD) and as a Total Artificial Heart (TAH).

Claims

1. A dual pump artificial heart blood pump apparatus for use in a mammalian cardiovascular system comprising:

a first pump, having an input and an output connectable to said cardiovascular system;

means for sensing pressure at the output of said first pump;

means for sensing pressure at the input of said first pump;

means for sensing flow rate through said first pump;

a second pump, having an input and an output connectable to said cardiovascular system;

means for sensing pressure at the output of said second pump;

means for sensing pressure at the input of said second pump;

means for sensing flow rate through said second pump; and

means for controlling the speed of said first and second pumps based on the pressures and flow rates detected by said sensing means.

2. The dual pump artificial heart blood pump apparatus of claim 1, further comprising:

means for determining a differential pressure across said first pump; and

means for determining a differential pressure across said second pump.

3. The dual pump artificial heart blood pump apparatus of claim 2, further comprising:

an electronic microprocessor, said microprocessor having a lookup table which tabulates the blood flow rate corresponding to varying blood pressure.

4. The dual pump artificial heart blood pump apparatus of claim 2, further comprising:

a microprocessor including a lookup table programmed for flow rates as a function of blood pressure.

5. The dual pump artificial heart blood pump apparatus of claim 2, further comprising:

a microprocessor for determining and controlling the rotational speed of the centrifugal blood pump in relation to tabulated pump performance, blood pressure and blood flow rate.

6. The dual pump artificial heart blood pump apparatus of claim 2, further comprising:

means for sensing the temperature of blood passing through said first pump; and

means for sensing the temperature of blood passing through said second pump.

7. The dual pump artificial heart blood pump apparatus of claim 1, further comprising means for changing a set point of the control system.

8. The dual pump artificial heart blood pump apparatus of claim 7, wherein said means for changing a set point of the control system comprises means for transmitting wireless remote control signals from outside the patient'"'"'s body.

9. The dual pump artificial heart blood pump apparatus of claim 7, wherein said means for changing a set point of the control system comprises means for transmitting control signals from outside the patient'"'"'s body through a subcutaneous transformer.

10. The dual pump artificial heart blood pump apparatus of claim 7, wherein said means for changing a set point of the control system comprises means for transmitting control signals from outside the patient'"'"'s body through a transcutaneous wire connection.

11. The dual pump artificial heart blood pump apparatus of claim 1, further comprising:

first means for sensing temperature at the output of said first blood pump;

means for controlling said first blood pump based upon a temperature sensed by said first means for sensing temperature;

second means for sensing temperature at the output of said second pump; and

means for controlling said second blood pump based upon a temperature sensed by said second means for sensing temperature.

12. The dual pump artificial heart blood pump apparatus of claim 1, further comprising:

means for sensing temperature in the blood passages of said first pump;

means for sensing temperature in the blood passages of said second pump.

13. The dual pump artificial heart blood pump apparatus of claim 1, further comprising:

first means for sensing temperature of a portion of said first blood pump, and means for controlling said first blood pump based upon a temperature sensed by said first means for sensing temperature;

second means for sensing temperature of a portion of said second blood pump, and means for controlling said second blood pump based upon a temperature sensed by said second means for sensing temperature.

14. The dual pump artificial heart blood pump apparatus of claim 13, wherein said first means for sensing temperature comprises means for sensing temperature of the motor of the first blood pump.

15. The dual pump artificial heart blood pump apparatus of claim 13, wherein said second means for sensing temperature comprises means for sensing temperature of the motor of the second blood pump.

16. The dual pump artificial heart blood pump apparatus of claim 13, wherein said first means for sensing temperature comprises means for sensing temperature of the bearings of the first blood pump.

17. The dual pump artificial heart blood pump apparatus of claim 13, wherein said second means for sensing temperature comprises means for sensing temperature of the bearings of the second blood pump.

18. The dual pump artificial heart blood pump apparatus of claim 13, wherein said first means for sensing temperature comprises means for sensing temperature of the exterior surface of the first blood pump.

19. The dual pump artificial heart blood pump apparatus of claim 13, wherein said second means for sensing temperature comprises means for sensing temperature of the exterior surface of the second blood pump.

20. The dual pump artificial heart blood pump apparatus of claim 13, wherein said first means for sensing temperature comprises means for sensing temperature of the passages of the first blood pump containing cooling fluid.

21. The dual pump artificial heart blood pump apparatus of claim 13, wherein said second means for sensing temperature comprises means for sensing temperature of the passages of the second blood pump containing cooling fluid.

22. A method of controlling dual centrifugal blood pumps operating as a heart blood pump, with a first centrifugal blood pump having an inlet connected to a cardiovascular system for receiving blood from the cardiovascular system and providing output to a respiratory system, and a second centrifugal blood pump having an inlet connected to the respiratory system to receive blood from the respiratory system and connected to deliver output to the cardiovascular system, the method comprising the steps of:

measuring a first pressure at the inlet of the first centrifugal blood pump and generating a first pressure signal indicative of said first pressure;

controlling the speed of operation of said second centrifugal blood pump responsive to said first pressure signal;

measuring a second pressure at the inlet of the second centrifugal blood pump and generating a second pressure signal indicative of said second pressure; and

controlling the speed of operation of said first centrifugal blood pump responsive to said second pressure signal.

23. The method of claim 22, further comprising the steps of measuring blood flow in said cardiovascular system, and controlling the speed of operation of said first and second centrifugal blood pumps responsive to said measured blood flow.