Biosensor

• US 6,447,657 B1
• Filed: 12/04/2000
• Issued: 09/10/2002
• Est. Priority Date: 12/04/2000
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Corporation (Roche Holding AG)
• Inventors: Hill, Brian S., Bhullar, Raghbir S., Wilsey, Christopher D.
• Primary Examiner(s): Tung, T.
• Assistant Examiner(s): NOGUEROLA, ALEXANDER STEPHAN
• Application Number:
  US09/729,296
• Publication Number:
  US 20020100684A1
• Time in Patent Office: 645 Days
• Field of Search: 204/403, 204/416, 204/409
• US Class Current: 204/403.01
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

A biosensor is provided that includes first and second plate elements, wherein each plate elements has first and second ends and first and second lateral borders. In addition, the biosensor includes a spacer positioned to lie between the first and second plate elements so that at least a portion of the first and second plate elements cooperate with one another to form opposite walls of a capillary space. Further, the first ends and at least a portion of the lateral borders define a fluid sample-receiving portion in communication with the capillary space. Electrodes are positioned in the capillary space of the biosensor.

Claims

1. A biosensor comprising:

first and second plate elements, said plate elements having first and second ends and first and second lateral borders, the first ends being generally concave in shape,

a spacer positioned to lie between the first and second plate elements spaced-apart from the first ends so that at least a portion of the first and second plate elements cooperate with one another to form opposite walls of a capillary space and the first ends and at least a portion of the opposite lateral borders define a fluid sample receiving portion in communication with the capillary space, and

electrodes positioned in the capillary space.

2. The biosensor of claim 1, wherein the lateral borders are straight.

3. The biosensor of claim 2, wherein the lateral borders are parallel relative to one another.

4. The biosensor of claim 1, wherein the lateral borders are curved.

5. The biosensor of claim 1, wherein the spacer is an adhesive.

13. The biosensor of claim 1, wherein at least a portion of the lateral borders are generally concave in shape.

6. A biosensor comprising:

first and second plate elements, said plate elements having first and second ends and first and second lateral borders,

a spacer positioned to lie between the first and second plate elements so that at least a portion of the first and second plate elements cooperate with one another to form opposite walls of a capillary space and the first ends and at least a portion of the opposite lateral borders define a fluid sample receiving portion in communication with the capillary space, and

electrodes positioned in the capillary space, wherein the ends of the first and second plate elements are off-set from one another.

7. The biosensor of claim 6, wherein the ends of the first and second plate elements are parallel relative to one another.

8. The biosensor of claim 6, wherein the lateral borders are straight.

9. The biosensor of claim 8, wherein the lateral borders are parallel relative to one another.

10. The biosensor of claim 8, wherein the lateral borders converge toward the first ends.

11. The biosensor of claim 6, wherein the lateral borders are curved.

12. The biosensor of claim 6, wherein the spacer is an adhesive.

14. A biosensor comprising:

first and second plate elements, said plate elements each having a body portion with opposite edges and first and second ends extending between the opposite edges and a tab extending from the first end of the body portion, the tab including an end and lateral borders extending between the end of the tab and the first end of the body portion, the lateral borders being spaced-apart from the opposite edges of the body portion,

electrodes positioned on the tab of said first plate element, and

a spacer positioned to lie between the plate elements so that the tabs form opposite walls of a capillary space extending between lateral borders and ends, wherein the ends and lateral borders cooperate to define a fluid sample receiving portion in communication with the capillary space.

15. The biosensor of claim 14, wherein the tabs are rectangular in shape.

16. The biosensor of claim 14, wherein the tabs are triangular in shape.

17. The biosensor of claim 14, wherein the tabs are curved.

18. A biosensor comprising:

first and second plate elements, said plate elements having tabs with ends and first and second lateral borders,

electrodes positioned on the tab of said first plate element, and

a spacer positioned to lie between the plate elements so that the tabs form opposite walls of a capillary space extending between lateral borders and ends, wherein the ends and lateral borders cooperate to define a fluid sample receiving portion in communication with the capillary space, wherein the tabs are rectangular in shape and the ends of the first and second plate elements are off-set relative to one another.

19. The biosensor of claim 18, wherein the lateral borders are the same length as the ends.

20. The biosensor of claim 18, wherein the tabs are rectangular in shape.

21. The biosensor of claim 18, wherein the tabs are triangular in shape.

22. The biosensor of claim 18, wherein the tabs are curved.

23. The biosensor of claim 18, wherein the lateral borders converge from the tab end toward the end of the body portion.

24. A biosensor comprising:

first and second plate elements, said plate elements including body portions with edges having a first dimension and opposite ends and tabs extending from one of the opposite ends, the tabs including lateral borders having a second dimension, which is less than the first dimension, the tabs being spaced-apart from the edges of the body portions,

electrodes positioned between the tabs, and

a spacer positioned to lie between the edges of the body portions so that the tabs form opposite walls of a capillary space, the spacer being spaced-apart from the lateral borders of the tabs and wherein the tabs cooperate to define a fluid sample receiving portion in communication with the capillary space.

25. The biosensor of claim 24, wherein the lateral borders are straight.

26. The biosensor of claim 25, wherein the tabs are rectangular in shape.

27. The biosensor of claim 24, wherein the tabs are triangular in shape.

28. The biosensor of claim 24, wherein the lateral borders are curved.

29. A biosensor comprising:

first and second plate elements, said plate elements including body portions with edges having a first dimension and opposite ends and tabs extending from one of the opposite ends, the tabs including lateral borders having a second dimension, which is less than the first dimension,

electrodes positioned between the tabs, and

a spacer positioned to lie between the edges of the body portions so that the tabs form opposite walls of a capillary space, wherein the tabs cooperate to define a fluid sample receiving portion in communication with the capillary space, wherein the lateral borders are straight and the tabs include ends and the ends of the tab have a third dimension that is equal to the second dimension.