Simultaneous cleaning and decontaminating compositions and methods

• US 6,448,062 B1
• Filed: 10/29/1999
• Issued: 09/10/2002
• Est. Priority Date: 10/30/1998
• Status: Expired due to Fees

• Current Assignee: Metrex Research, LLC (Envista Holdings Corporation)
• Original Assignee: Metrex Research, LLC (Envista Holdings Corporation)
• Inventors: Yu, Zhi-Jian, Huth, Stanley William
• Primary Examiner(s): Redding, David A.
• Application Number:
  US09/430,398
• Time in Patent Office: 1,047 Days
• Field of Search: 510/161, 510/162, 510/382, 510/108, 510/109, 510/114, 510/363, 510/367, 510/374, 510/375, 510/392, 510/401, 435/264, 134/42
• US Class Current: 435/264
• CPC Class Codes: A01N 37/16 containing the group; Thio analogues thereof
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A61L 2/18 Liquid substances or solutions comprising solids or dissolved gases
• CPC Class Codes: A61L 2/186 Peroxide solutions
• CPC Class Codes: A61L 2202/24 Medical instruments, e.g. endoscopes, catheters, sharps
• CPC Class Codes: A61M 1/169 using chemical substances
• CPC Class Codes: C11D 2111/20 Industrial or commercial equipment, e.g. reactors, tubes or engines
• CPC Class Codes: C11D 3/386 Preparations containing enzymes , e.g. protease or amylase
• CPC Class Codes: C11D 3/3945 Organic per-compounds C11D3/3902 takes precedence
• CPC Class Codes: C11D 3/48 Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Abstract

A composition for simultaneous cleaning and decontaminating a device. The composition is a per-compound oxidant in an amount effective for decontaminating the device and an enzyme in an amount effective for cleaning the device. The device may be a medical device such as an endoscope or kidney dialyzer and a plurality of devices can be cleaned using the same composition. The composition may additionally contain a corrosion inhibitor in an amount effective to prevent corrosion of a metal, a chelator, a buffer, a dye and combinations thereof.

Claims

1. A method for simultaneously cleaning and decontaminating a kidney dialyzer comprising contacting said dialyzer with a solution that simultaneously cleans and decontaminates said dialyzer, said solution comprising a mixture of H₂O₂ at about 0.5-1.5%^w/w and PAA at about 0.05-3.0%^w/w and human pepsin at about 0.00001-0.10 A.U./ml and having a pH between 1-6.

2. A composition for simultaneously cleaning and decontaminating a kidney dialyzer comprising a mixture of H₂O₂ at about 0.5-1.5%^w/w and PAA at about 0.05-3.0%^w/w and human pepsin at about 0.00001-0.10 A.U./ml and having a pH between 1-6.

3. A method for simultaneously cleaning and decontaminating a kidney dialyzer comprising contacting said dialyzer with a solution that simultaneously cleans and decontaminates said dialyzer, said solution comprising a mixture of H₂O₂ at about 0.5-1.5%^w/w and PAA at about 0.05-3.0%^w/w and human trypsin at about 0.00001-0.10 A.U./ml and having a pH between 6-9.

4. A composition for simultaneously cleaning and decontaminating a kidney dialyzer comprising a mixture of H₂O₂ at about 0.5-1.5%^w/w and PAA at about 0.05-3.0%^w/w and human trypsin at about 0.00001-0.10 A.U./ml and having a pH between 6-9.