Human proteases and polynucleotides encoding the same

• US 6,448,388 B1
• Filed: 08/15/2001
• Issued: 09/10/2002
• Est. Priority Date: 08/16/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Friddle, Carl Johan, Hilbun, Erin
• Primary Examiner(s): Prouty, Rebecca E.
• Assistant Examiner(s): SWOPE, SHERIDAN
• Application Number:
  US09/930,872
• Time in Patent Office: 391 Days
• Field of Search: 435/219, 435/226, 536/23.2
• US Class Current: 536/23.2
• CPC Class Codes: C12N 9/64 derived from animal tissue

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding an amino acid sequence drawn from the group consisting of SEQ ID NOS:

2 and 4.

3. An isolated nucleic acid molecule according to claim 1 wherein said nucleotide sequence is present in cDNA.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

4; and

(b) hybridizes under stringent conditions of hybridization to filter-bound DNA in 0.5 M NaHPO₄, 7% SDS, 1mM EDT at 65°

C. and washing in 0.1×

SSC/1% SDS at 68°

C. to the nucleotide sequence of SEQ ID NO;

3 or the complement thereof.

4. An isolated nucleic acid molecule encoding the amino acid sequence presented in SEQ ID NO:

4.

5. An isolated nucleic acid molecule encoding the amino acid sequence presented in SEQ ID NO:

2.