Ultrasonic transmission guide wire

• US 6,450,975 B1
• Filed: 12/30/1999
• Issued: 09/17/2002
• Est. Priority Date: 12/30/1999
• Status: Active Grant

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Cornish, Wayne, Siegel, Robert J., Gesswein, Douglas, Brennan, Lawrence
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US09/475,521
• Time in Patent Office: 992 Days
• Field of Search: 600/585, 600/434, 606/159, 606/169, 604/20, 604/22
• US Class Current: 600/585
• CPC Class Codes: A61B 17/22012 in direct contact with, or very close to, the obstruction or concrement for removing obstructions in blood vessels by laser A61B18/245
• CPC Class Codes: A61B 2017/22015 with details of the transmission member
• CPC Class Codes: A61B 2017/22018 segmented along its length
• CPC Class Codes: A61B 2017/320084 Irrigation sleeves
• CPC Class Codes: A61B 2017/320088 with acoustic insulation, e.g. elements for damping vibrations between horn and surrounding sheath
• CPC Class Codes: G10K 11/24 for conducting sound through solid bodies, e.g. wires

Abstract

The ultrasonic angioplasty transmission guide wire has regions of reduced cross-sectional diameter to improve flexibility and to compensate for degradation of longitudinal displacement due to acoustic losses along the length of the guide wire. The guide wire has a core of ultrasonic transmission material and an outer jacket surrounding a usable portion of the elongated shaft. The outer jacket is formed of a shrink tubing. At the proximal end are disposed threads configured to connect to a connecting device for an ultrasound transducer. The distal end comprises a smooth ball tip for atraumatic application of ultrasound energy to biological tissue. In one embodiment, the guide wire is formed of stainless steel. In another, the guide wire is formed at least partially of a superelastic metal alloy and in one case is formed at least partially of a shape memory alloy that exhibits superelastic properties when in its martensitic state. In one preferred embodiment, the guide wire is formed of a nickel-titanium alloy.

Claims

1. An ultrasound transmission guide wire for use in an ultrasonic angioplasty device, the ultrasound transmission guide wire having an elongated shaft, a proximal end configured to be connected to an ultrasound transducer, and a distal end for applying ultrasonic energy to an area of vascular lesion, the ultrasound transmission guide wire comprising:

a distal portion with at least one amplification region of reduced cross-sectional diameter, wherein the location and dimensions of each amplification region are selected so as to reduce the possibility of breakage of the ultrasound transmission guide wire due to transverse vibrations of ultrasonic energy;

a core of ultrasonic transmission material; and

a non-metallic outer jacket in contact with and surrounding the core along each amplification region, the outer jacket having a substantially constant thickness, wherein the outer jacket further reduces the possibility of breakage of the ultrasound transmission guide wire due to transverse vibrations of ultrasonic energy.

2. The ultrasound transmission guide wire of claim 1 wherein the ultrasound transmission guide wire comprises threads disposed at its proximal end, the threads configured to connect to a connecting device for an ultrasound transducer to thereby communicate ultrasonic energy to the elongated shaft and to the distal end of the ultrasound transmission guide wire.

3. The ultrasound transmission guide wire of claim 1 wherein the ultrasound transmission guide wire comprises a first generally cylindrical section having a first cross-sectional diameter, and a second generally cylindrical section distal to the first section and having a second cross-sectional diameter that is smaller than the first cross-sectional diameter, the amplification region being formed at a proximal portion of the second generally cylindrical section.

4. The ultrasound transmission guide wire of claim 3 further comprising a conically tapered section interposed between the first and second cylindrical sections.

5. The ultrasound transmission guide wire of claim 4 further comprising a plurality of conically tapered sections interposed between adjacent ones of the plurality of generally cylindrical sections.

6. The ultrasound transmission guide wire of claim 1 further comprising a plurality of generally cylindrical sections, each of the plurality of generally cylindrical sections having reduced cross-sectional diameter relative to a proximal adjacent section resulting in a plurality of amplification regions in the cylindrical sections of reduced cross-sectional diameter.

7. The ultrasound transmission guide wire of claim 1 further comprising an enlarged application portion located at the distal end of the elongated shaft, the enlarged application portion configured to apply ultrasonic energy to a biological lesion.

8. The ultrasound transmission guide wire of claim 7 wherein the enlarged application portion comprises a rounded portion having a diameter exceeding the diameter of the elongated shaft immediately proximal to the rounded portion.

9. The ultrasound transmission guide wire of claim 8 wherein the enlarged application portion comprises a smooth ball tip having a diameter exceeding the diameter of the elongated shaft immediately proximal to the ball tip.

10. The ultrasound transmission guide wire of claim 1 wherein the outer jacket is formed of shrink tubing.

11. The ultrasound transmission guide wire of claim 1 wherein the outer jacket is formed of rubber.

12. The ultrasound transmission guide wire of claim 1 wherein the outer jacket is formed of plastic.

13. The ultrasonic angioplasty catheter device of claim 1 wherein the ultrasound transmission guide wire is formed at least partially of a superelastic metal alloy.

14. The ultrasonic angioplasty catheter device of claim 1 wherein the ultrasound transmission guide wire is formed at least partially of a shape memory alloy that exhibits superelastic properties when in its martensitic state.

15. The ultrasonic angioplasty catheter device of claim 14 wherein the ultrasound transmission guide wire is formed of a nickel-titanium alloy.

16. An ultrasound transmission guide wire having an elongated shaft, a proximal end configured to be connected to an ultrasound transducer, and a distal end for applying ultrasonic energy, the ultrasound transmission guide wire comprising:

a distal portion with at least one amplification region of reduced cross-sectional diameter, wherein the location and dimensions of each amplification region are selected so as to reduce the possibility of breakage of the ultrasound transmission guide wire due to transverse vibrations of ultrasonic energy;

a core of ultrasonic transmission material;

an enlarged application portion located at the distal end of the elongated shaft, the enlarged application portion configured to apply ultrasonic energy; and

a non-metallic outer jacket in contact with and surrounding the core along each amplification region, wherein the outer jacket further reduces the possibility of breakage of the ultrasound transmission guide wire due to transverse vibrations of ultrasonic energy.

17. The ultrasound transmission guide wire of claim 16 further comprising a plurality of generally cylindrical sections, each of the plurality of generally cylindrical sections having reduced cross-sectional diameter relative to a proximal adjacent section resulting in a plurality of amplification regions in the cylindrical sections of reduced cross-sectional diameter.

18. The ultrasound transmission guide wire of claim 17 further comprising a conically tapered section interposed between a pair of cylindrical sections.

19. The ultrasound transmission guide wire of claim 17 further comprising a plurality of conically tapered sections interposed between adjacent ones of the plurality of generally cylindrical sections.

20. The ultrasound transmission guide wire of claim 16 wherein the enlarged application portion comprises a smooth ball tip having a diameter exceeding the diameter of the elongated shaft immediately proximal to the ball tip.

21. The ultrasound transmission guide wire of claim 16 wherein the ultrasound transmission guide wire comprises threads disposed at its proximal end, the threads configured to connect to a connecting device for an ultrasound transducer to thereby communicate ultrasonic energy to the elongated shaft and to the distal end of the ultrasound transmission guide wire.

22. The ultrasonic angioplasty catheter device of claim 16 wherein the ultrasound transmission guide wire is formed at least partially of a superelastic metal alloy.

23. The ultrasonic angioplasty catheter device of claim 16 wherein the ultrasound transmission guide wire is formed at least partially of a shape memory alloy that exhibits superelastic properties when in its martensitic state.

24. The ultrasonic angioplasty catheter device of claim 23 wherein the ultrasound transmission guide wire is formed of a nickel-titanium alloy.

25. An ultrasonic angioplasty catheter device comprising an elongate flexible catheter having a proximal end, a distal end, and at least one lumen extending longitudinally therethrough, the device comprising:

an ultrasound transmission guide wire extending through the lumen and having a distal end with an enlarged head for applying ultrasonic energy to a lesion, and a proximal end configured to be connected to an ultrasound generating device, the ultrasound transmission guide wire having a distal portion with at least one amplification region of reduced cross-sectional diameter where transverse vibration of ultrasonic energy transmitted by the ultrasound transmission guide wire is amplified, wherein the location and dimensions of each amplification region are selected so as to reduce the possibility of breakage of the ultrasound transmission guide wire due to the transverse vibration;

wherein the ultrasound transmission guide wire comprises;

an elongated shaft;

a core of ultrasonic transmission material; and

an outer jacket surrounding the core along each amplification region.

26. The ultrasonic angioplasty catheter device of claim 25 wherein the ultrasound transmission guide wire is formed at least partially of a superelastic metal alloy.

27. The ultrasonic angioplasty catheter device of claim 25 wherein the ultrasound transmission guide wire is formed at least partially of a shape memory alloy that exhibits superelastic properties when in its martensitic state.

28. The ultrasonic angioplasty catheter device of claim 27 wherein the ultrasound transmission guide wire is formed of a nickel-titanium alloy.