Pressure Sensitive Adhesive Composition

• US 6,451,883 B1
• Filed: 02/28/2000
• Issued: 09/17/2002
• Est. Priority Date: 08/29/1997
• Status: Expired due to Term

• Current Assignee: Coloplast A/S
• Original Assignee: Coloplast A/S
• Inventors: Ciok, Danuta, Chen, Fei
• Primary Examiner(s): Seidleck, James J.
• Assistant Examiner(s): RAJGURU, UMAKANT K
• Application Number:
  US09/485,697
• Time in Patent Office: 932 Days
• Field of Search: 523/111, 524/22, 524/31, 524/25, 524/47, 524/45, 524/503
• US Class Current: 524/31
• CPC Class Codes: A61F 5/443 having adhesive seals for securing to the body, e.g. of hydrocolloid type, e.g. gels, starches, karaya gums adhesives or sealing pads therefor A61L24/00
• CPC Class Codes: A61L 15/225 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 15/585 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 15/60 Liquid-swellable gel-forming materials, e.g. super-absorbents
• CPC Class Codes: A61L 24/0031 Hydrogels or hydrocolloids
• CPC Class Codes: A61L 24/043 Mixtures of macromolecular materials
• CPC Class Codes: A61L 24/06 obtained by reactions only involving carbon-to-carbon unsaturated bonds A61L24/043, A61L24/046 take precedence
• CPC Class Codes: A61L 2400/14 Adhesives for ostomy devices
• CPC Class Codes: C08L 2205/02 containing two or more polymers of the same C08L -group
• CPC Class Codes: C08L 23/20 having four to nine carbon atoms
• CPC Class Codes: C08L 2666/24 Graft or block copolymers according to groups C08L51/00, C08L53/00 or C08L55/02; Derivatives thereof
• CPC Class Codes: C08L 2666/28 Non-macromolecular organic substances
• CPC Class Codes: C08L 5/00 Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
• CPC Class Codes: C08L 5/06 Pectin; Derivatives thereof
• CPC Class Codes: C08L 53/02 of vinyl-aromatic monomers and conjugated dienes
• CPC Class Codes: C09J 123/20 having four to nine carbon atoms
• CPC Class Codes: C09J 123/22 Copolymers of isobutene; Butyl rubber ; Homo- or copolymers of other iso-olefines

Abstract

A pressure sensitive adhesive composition suitable for medical purposes comprising a rubbery elastomeric base and one or more water soluble or water swellable hydrocolloids, the adhesive composition comprising a substantially homogeneous mixture of 35-50% of one or more polybutenes, 5-20% of one or more styrene copolymers, and 20-60% of one or more hydrocolloids has very good properties as an adhesive for ostomy appliances.

Claims

1. A pressure sensitive adhesive composition suitable for medical purposes consisting of a homogenous mixture of 25% by weight—

60% by weight of one or more polybutenes having a Flory molecular weight from 50,000 to 60,000, 3% by weight—

35% by weight of one or more styrene copolymers, and 20% by weight—

60% by weight of one or more hydrocolloids of the total weight of the adhesive composition.

2. The adhesive composition as claimed in claim 1 wherein the styrene copolymer is a styrene-butadiene-styrene block copolymer or a styrene-isoprene-styrene block copolymer.

3. The adhesive composition as claimed in claim 2 wherein the styrene copolymer is a styrene-isoprene-styrene block copolymer.

4. The adhesive composition as claimed in claim 1 wherein the butenes are conjugated butadiene polymer selected from the group consisting of polybutadiene and polyisoprene.

5. The adhesive composition as claimed in claim 1 wherein the hydrocolloids are selected from the group consisting of naturally occurring hydrocolloids, semisynthetic hydrocolloids and synthetic hydrocolloids.

6. The adhesive composition as claimed in claim 5 wherein the hydrocolloids are selected from the group consisting of guar gum, locust bean gum (LBG), pectin, alginates, gelatine, xanthan and gum karaya and mixtures thereof;

cellulose derivatives, sodium starch glycolate, polyvinylalcohol and polyethylene glycol and mixtures thereof.

7. An ostomy appliance for placing on the abdomen of a patient for use in collecting discharge of visceral contents comprising an adhesive composition containing a rubbery elastomeric base and one or more water soluble or water swellable hydrocolloids, said adhesive composition consisting of a homogeneous mixture of 25% by weight—

60% by weight of one or more polybutenes having a Flory molecular weight from 50,000 to 60,000, 3% by weight—

35% by weight of one or more styrene copolymers, and 20% by weight—

60% by weight of one or more hydrocolloids of the total weight of the adhesive composition.

9. The adhesive composition of claim 7, wherein the polybutene is a conjugated butadiene polymer selected from the group consisting of polybutadienes and polyisoprenes.

10. The adhesive composition of claim 7, wherein the styrene copolymer is a styrene-butadiene-styrene block copolymer or a styrene-isoprene-styrene block copolymer.

8. A method for securing ostomy appliances to the skin and for sealing around an ostomy, for securing wound dressings or wound drainage bandages to the skin, for securing devices for collecting urine to the skin, or for securing orthoses or prostheses to the skin, comprising using an adhesive composition comprising consisting of a homogeneous mixture of 35% by weight—

50% by weight of one or more polybutenes having a Flory molecular weight from 50,000 to 60,000, 5% by weight—

20% by weight of one or more styrene copolymers, and 20% by weight—

60% by weight of one or more hydrocolloids of the total weight of the adhesive composition, wherein the mixture of one or more polybutenes and one or more styrene copolymers and one or more hydrocolloids constitutes the adhesive composition, for securing the ostomy appliances to the skin and for sealing around the ostomy, for securing the wound dressings or the wound drainage bandages to the skin, for securing the devices for collecting urine to the skin, or for securing the orthoses or the prostheses to the skin.

11. A pressure sensitive adhesive composition suitable for medical purposes by weight of a mixture of polyisobutylene having a Flory molecular weight from 50,000 to 60,000 and styrene-isoprene-styrene block copolymer and 50% by weight of a mixture of hydrocolloids.

12. The adhesive composition of claim 11, wherein the mixture of hydrocolloids comprises gelatine, pectin and CMC.