High mass transfer electrosprayer

• US 6,454,193 B1
• Filed: 04/20/2000
• Issued: 09/24/2002
• Est. Priority Date: 04/23/1999
• Status: Expired due to Fees

• Current Assignee: Battelle Memorial Institute
• Original Assignee: Battellepharma, Inc. (Battelle Memorial Institute)
• Inventors: Trees, Gregory A., Dvorsky, James E., Busick, David R., Saunders, James H.
• Primary Examiner(s): EVANS, ROBIN OCTAVIA
• Application Number:
  US09/553,541
• Time in Patent Office: 887 Days
• Field of Search: 239/3, 239/690, 239/690.1, 239/692, 239/695, 239/705, 239/706, 239/708, 239/696
• US Class Current: 239/690
• CPC Class Codes: A61L 9/14 using sprayed or atomised substances including air-liquid contact processes
• CPC Class Codes: A61M 1/265 inducing Taylor vortices
• CPC Class Codes: A61M 15/02 with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
• CPC Class Codes: B05B 5/0255 spraying and depositing by electrostatic forces only

Abstract

A electrohydrodynamic aerosol sprayer wherein a gas flow deflector is used for creating a gas flow past the spray nozzle to stabilize the Taylor cone and to transport at least a portion of the aerosol away from the region downstream of the spray nozzle. This stabilization of the cone and transport of aerosol improves the droplet size and distribution and may also reduce the deposit of droplets on the internal components of the device.

Claims

1. A high mass transfer electrohydrodynamic aerosol sprayer comprising:

a spray nozzle in fluid communication with a source of fluid to be aerosolized, the spray nozzle having at least one spray tip near which the fluid exits the spray nozzle, forms a Taylor cone and is aerosolized by electrohydrodynamic spraying;

a gas flow deflector for directing a gas past the spray tip and sweeping at least a portion of the aerosol away from the spray tip, and

a first voltage source maintaining the spray nozzle at a negative potential.

2. The high mass transfer electrohydrodynamic aerosol sprayer of claim 1 wherein the spray nozzle is an elongated tube in fluid communication with a source of fluid at an upstream end thereof, the spray tip is located at a downstream end of the elongated tube and wherein the gas flow deflector directs the gas along at least a portion of the spray nozzle and past the spray tip.

3. The high mass transfer electrohydrodynamic aerosol sprayer of claim 2 wherein the gas flow deflector directs the gas along and substantially parallel to at least a portion of the spray nozzle and past the spray tip substantially completely around the spray nozzle.

4. The high mass transfer electrohydrodynamic aerosol sprayer of claim 3 wherein the gas flow deflector directs the gas in a laminar flow.

5. The high mass transfer electrohydrodynamic aerosol sprayer of claim 1 wherein the aerosol moves away from the spray tip at an aerosol velocity and the gas flow deflector directs the gas past the spray tip at a gas velocity greater than the average aerosol velocity one centimeter downstream of the spray tip.

6. The high mass transfer electrohydrodynamic aerosol sprayer of claim 5 wherein the gas flow deflector directs the gas in a laminar flow along at least a portion of the spray nozzle and past the spray tip substantially completely around the spray nozzle.

7. The high mass transfer electrohydrodynamic aerosol sprayer of claim 1 further comprising:

a discharge electrode; and

a second voltage source maintaining the discharge electrode at a positive potential relative to the potential of the spray nozzle.

8. The high mass transfer electrohydrodynamic aerosol sprayer of claim 1 further comprising multiple spray nozzles.

9. A high mass transfer electrohydrodynamic aerosol sprayer comprising:

a spray nozzle in fluid communication with a source of fluid to be aerosolized, the spray nozzle having at least one spray tip near which the fluid exits the spray nozzle, forms a Taylor cone and is aerosolized by electrohydrodynamic spraying; and

a gas flow deflector for separating a gas flow into at least two portions, for directing a first portion of the gas past the spray tip to sweep at least a portion of the aerosol downstream from the spray tip and for further directing the second portion of the gas away from the spray tip but thereafter into contact with the first portion of the gas and the aerosol downstream of the spray tip.

10. The high mass transfer electrohydrodynamic aerosol sprayer of claim 9 wherein the spray nozzle has a least one spray tip near which the fluid exits the spray nozzle, forms a Taylor cone which is elongated away from the spray tip in a preferred direction and is aerosolized by electrohydrodynamic spraying and wherein

the gas flow deflector is further capable of directing the first portion of the gas past the spray tip substantially parallel to the preferred direction of the Taylor cone.

11. The high mass transfer electrohydrodynamic aerosol sprayer of claim 9 wherein the gas flow deflector directs the first portion of gas substantially completely around the spray nozzle.

12. The high mass transfer electrohydrodynamic aerosol sprayer of claim 11 wherein the gas flow deflector directs the second portion of gas substantially completely around the first portion of gas and the aerosol downstream of the spray tip.

13. The high mass transfer electrohydrodynamic aerosol sprayer of claim 9 which additionally includes a plurality of spray nozzles and a plurality of spray tips and wherein the gas flow deflector is capable of directing the first portion of gas substantially completely around the plurality of spray tips and of directing the second portion of gas substantially completely around the first portion of gas and the aerosol downstream of the spray tips.

14. The high mass transfer electrohydrodynamic aerosol sprayer of claim 9 wherein the gas flow deflector surrounds the spray tip and has an inlet end and an outlet end and wherein the deflector is designed such that the gas velocity is lower near the outlet end than near the inlet end.

15. The high mass transfer electrohydrodynamic aerosol sprayer of claim 14, wherein the cross sectional area available for the gas flow near the inlet end of the deflector is less than the cross sectional area near the outlet.

16. The high mass transfer electrohydrodynamic aerosol sprayer of claim 9 wherein the flow resistance of the gas flow deflector is such that the first portion of gas is smaller than the second portion of gas.