Doppler velocimeter for blood flow

• US 6,454,722 B1
• Filed: 08/29/2000
• Issued: 09/24/2002
• Est. Priority Date: 08/31/1999
• Status: Active Grant

• Current Assignee: Canon Ayutthaya Limited (Canon Inc.)
• Original Assignee: Canon Ayutthaya Limited (Canon Inc.)
• Inventors: Tanaka, Shinya, Numajiri, Yasuyuki
• Primary Examiner(s): Shaver, Kevin
• Assistant Examiner(s): MALLARI, PATRICIA C
• Application Number:
  US09/650,348
• Time in Patent Office: 756 Days
• Field of Search: 600/504, 600/558, 600/399, 600/400, 600/404, 600/405, 351/221
• US Class Current: 600/504
• CPC Class Codes: A61B 3/1241 specially adapted for observation of ocular blood flow, e.g. by fluorescein angiography

Abstract

A Doppler velocimeter includes an illumination system for illuminating a blood vessel with a light beam, a detector for detecting Doppler-shifted scattered light produced from blood flowing in the blood vessel, and a processor for obtaining a blood flow velocity by analyzing a signal from said detector. The processor compares an actual power spectrum obtained by frequency-analyzing the signal with a theoretical power spectrum obtained using a frequency as a parameter while changing the parameter.

Claims

1. A Doppler velocimeter comprising:

an illumination system for illuminating a blood vessel with a light beam;

a detector for detecting Doppler-shifted scattered light produced from blood flowing in the blood vessel; and

a processor for obtaining a blood flow velocity by analyzing a signal from said detector, wherein said processor compares an actual power spectrum obtained by frequency-analyzing the signal with a theoretical power spectrum obtained using a frequency as a parameter while changing the parameter.

2. A velocimeter according to claim 1, wherein said detector detects said scattered light with a pupil having a predetermined shape and size, and the theoretical power spectrum has a curve of a slope that reflects the shape or size of the pupil.

3. A velocimeter according to claim 1, wherein said processor compares the actual power spectrum obtained by frequency-analyzing the signal with the theoretical power spectrum obtained using the frequency and the direction of the blood vessel with reference to an apparatus as parameters while changing the parameters.

4. A velocimeter according to claim 1, wherein the blood vessel is present on a fundus of an eye to be examined.

5. A velocimeter according to claim 1, wherein said processor repeats the comparison while changing the parameter, and computes a blood flow velocity using the frequency when it is determined as a result of comparison that the two power spectra best fit.

6. A velocimeter according to claim 5, wherein said processor compares a fitting curve generated in consideration of sufficiently high-frequency noise with a curve of the actual power spectrum.

7. A velocimeter according to claim 5, wherein the comparison is done by comparing a square sum of differences.

8. A velocimeter according to claim 5, wherein the frequency analysis includes FFT analysis.

9. A velocimeter according to claim 2, further comprising a stop which is inserted in front of said detector and forms the entrance pupil.

10. A velocimeter according to claim 1, wherein said detector consists of a single photomultiplier.

11. A velocimeter according to claim 1, wherein said detector has a plurality of photomultipliers.

12. A velocimeter according to claim 11, wherein said detector has two photomultipliers, and said processor computes to maintain a theoretical ratio between cutoff frequencies of the two photomultipliers upon comparison.

14. A fundus blood flow meter having the Doppler velocimeter according to any one of claims 1 to 13.

15. An eye examining apparatus having the Doppler velocimeter according to any one of claims 1 to 13.

13. A Doppler velocimeter comprising:

an illumination system for illuminating a fluid with a light beam;

a detector for detecting Doppler-shifted scattered light produced from the fluid; and

a processor for obtaining a flow velocity of the fluid by analyzing a signal from said detector, wherein said processor compares an actual power spectrum obtained by frequency-analyzing the signal with a theoretical power spectrum obtained using a frequency as a parameter while changing the parameter.