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Methods for delivering in vivo uniform dispersed embolic compositions of high viscosity

  • US 6,454,738 B1
  • Filed: 05/19/2000
  • Issued: 09/24/2002
  • Est. Priority Date: 05/21/1999
  • Status: Expired due to Term
First Claim
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1. A method for embolizing a vascular site, said method comprising:

  • (a) preparing an embolic composition comprising (1) a biocompatible polymer, (2) a biocompatible solvent which solubilizes said polymer, and (3) a water insoluble contrast agent which is suspended in said composition, wherein said embolic composition has a viscosity of at least 150 centistokes at 40°

    C., (b) heating and mixing the embolic composition to at least 40°

    C. to form a uniform suspension, (c) transferring the heated embolic composition to a delivery catheter having a proximal end and a distal end, wherein the distal end of the delivery catheter is positioned at the vascular site to be embolized, and (d) injecting the heated embolic composition into said vascular site in sufficient amounts to embolize said vascular site.

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