Implantable blood flow monitoring system

• US 6,458,086 B1
• Filed: 04/05/2000
• Issued: 10/01/2002
• Est. Priority Date: 04/05/2000
• Status: Expired due to Term

• Current Assignee: Kenneth Lawrence Franco, Tofy Mussivand
• Original Assignee: Kenneth Lawrence Franco, Tofy Mussivand
• Inventors: Franco, Kenneth Lawrence, Mussivand, Tofy
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/543,618
• Time in Patent Office: 909 Days
• Field of Search: 600/301, 600/407, 600/438, 600/454, 600/462, 600/468, 600/465, 600/504, 600/505, 600/509, 600/510, 600/513, 600/515, 600/519, 600/526, 600/527
• US Class Current: 600/526
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/4472 Wireless probes
• CPC Class Codes: A61B 8/543 involving acquisition triggered by a physiological signal
• CPC Class Codes: A61B 8/56 Details of data transmission or power supply

Abstract

An implantable blood flow monitoring system for providing synchronized blood vessel flow and myocardial wall contractility data to an external monitor independent of transcutaneous leads. Synchronized electrocardiogram data allows and provides comprehensive monitoring. A means is provided for transmitting synchronized cardiac function data and blood flow data to a distant remote location to facilitate continual physician monitoring.

Claims

1. A blood flow monitoring system comprising:

an implantable blood flow sensor;

an implantable myocardial contractility sensor;

a first microcontroller in communication with said blood flow sensor and said conductility sensor collecting data from said blood flow sensor and said contactility sensor, wherein the data is coupled with time stamp information; and

a first radio frequency transceiver communicating the data and the time stamp information to an external monitor,

said external monitor comprising;

an elecmocardiogram sensor;

a second radio frequency transceiver receiving the data and time stamp information;

a third radio fluency transceiver transmitting the time stamped or synchronized information to a distant receiver; and

a microcontroller coupled to said second and third transceivers and said electrocardiogram sensor, wherein said microcontroller synchronizes output from said electrocardiogram sensor and the data to calculate in combination at least two synchronized parameters selected from a group consisting of blood flow, heart wall motion and electrocardiogram.

2. The blood flow monitoring system of claim 1 wherein said myocardial contractility sensor is a piezoelectric crystal.

3. The blood flow monitoring system of claim 1 further comprising an implantable microcontroller manipulating the data and the time stamp information prior to communicating by said first radio frequency transceiver.

4. The blood flow monitoring system of claim 1 wherein said first radio frequency transceiver is implanted.

5. The blood flow monitoring system of claim 1 further comprising a radio frequency communication system between said external monitor and an implanted blood flow meter.

6. The blood flow monitoring system of claim 1 further comprising a radio frequency communication system between said external monitor and a distant remote receiver.

7. A method of monitoring blood flow comprising the steps of:

measuring a blood flow in blood vessels;

measuring a myocardial wall motion;

measuring an electrocardiogram using an external monitor;

synchronizing at least two measurements selected from a group consisting of, blood flow, myocardial wall motion and electrocardiogram; and

communicating at least two synchronized measurements to an external monitor and to a distant remote receiver.

8. The method of claim 7 wherein the blood flow is measured with a first ultrasonic signal reflected from the blood vessel to a blood flow sensor.

9. The method of claim 8 wherein said blood flow sensor is implanted.

10. The method of claim 8 wherein the first ultrasonic signal reflected is processed by an implanted microcontroller.

11. The method of claim 10 further comprising time stamping the first ultrasonic signal reflected.

12. The method of claim 7 wherein the myocardial wall motion is measured with an implanted ultrasonically excited piezoelectric crystal sensor with a second ultrasonicaly reflected signal being received by at least one implanted ultrasonically unexcited piezoelectric sensor.

13. The method of claim 12 wherein the second reflected ultrasonic signal is processed by an implanted microcontroller.

14. The method of claim 13 further comprising time stamping the second reflected ultrasonic signal.

15. The method of claim 13 wherein an integrated microcontroller processes the second reflected ultrasonic signal and a first signal reflected from the blood vessel to a blood flow sensor relating to blood flow.

16. The method of claim 7 wherein the at least two synchronized measurements are communicated with a radio frequency transceiver.

17. The method of claim 16 wherein said radio frequency transceiver is implanted.

18. The method of claim 16 wherein said radio frequency transceiver communicates time stamped blood flow data.

19. The method of claim 16 wherein said radio frequency transceiver communicates time stamped myocardial wall motion data.

20. The method of claim 7 further comprising the step of:

transmitting output of said external display monitor to a distant radio frequency receiver.

21. A blood flow monitoring system comprising:

a first electronic interface exciting a blood flow sensor with a first ultrasonic signal and receiving a first reflected ultrasonic signal from said blood flow sensor;

a second electronic interface exciting a piezoelectric crystal sensor of an implanted array of piezoelectric sensors with a second ultrasonic signal and receiving a second reflected ultrasonic signal from non-excited piezoelectric sensors of said array;

a microcontroller coupled to said first electronic interface for computing blood flow and to said second electronic interface for computing myocardial wall motion; and

a radio frequency communication transceiver in communication with an external monitor receiving external time stamp synchronization data therefrom and transmitting synchronized blood flow and myocardial wall motion data thereto.

22. The system of claim 21 further comprising a plurality of blood flow sensors.

23. The system of claim 21 wherein said first and said second electronic interfaces form a unitary interface.

24. The system of claim 21 further comprising an external electrocardiogram system synchronized with blood flow and myocardial wall motion data.

25. The system of claim 24 further comprising a distant remote receiver able to receive the synchronized electrocardiogram, blood flow and myocardial wall motion data.