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Method and apparatus for making nucleic acid arrays

  • US 6,458,583 B1
  • Filed: 09/09/1998
  • Issued: 10/01/2002
  • Est. Priority Date: 09/09/1998
  • Status: Expired due to Fees
First Claim
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1. A method for depositing a pre-made nucleic acid onto a substrate surface wherein said deposited nucleic acid is capable of hybridizing to its complement, said method comprising:

  • loading an aqueous fluid composition of said pre-made nucleic acid into thermal inkjet head comnprising an orifice and a firing chamber by contacting said orifice with said fluid composition in a manner sufficient for said fluid composition to flow through said orifice into said firing chamber;

    positioning said thermal inkjet head filled with said fluid composition of said pre-made nucleic acid in opposing relation to said substrate surface, and actuating said thermal inkjet head in a maniner sufficient to expel a volume of said composition onto said substrate surface, whereby said pre-made nucleic acid is deposited on said substrate surface, wherein said deposited nucleic acid is capable of hybridizing to its complement.

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