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Liquid sample dispensing methods for precisely delivering liquids without crossover

  • US 6,463,969 B1
  • Filed: 04/10/2001
  • Issued: 10/15/2002
  • Est. Priority Date: 04/10/2001
  • Status: Expired
First Claim
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1. A method for reducing carryover of first target vessel liquid contained in a first target vessel and a sampling pipette containing source liquid, the method comprising:

  • spinning the first target vessel so that first target vessel liquid contained therein is displaced away from the central portion of the target vessel;

    forming a first droplet of source liquid at the nozzle of the sampling pipette;

    lowering the sampling pipette into the central portion of the target vessel a distance sufficient to cause the first droplet of source liquid to contact the bottom of the first target vessel without the sampling pipette or the droplet touching first target vessel liquid disposed therein, so that the first droplet of source liquid is spun off from the sampling pipette into the target vessel.

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