Lancet for capillary puncture blood samples
First Claim
1. A lancet for obtaining a drop of blood for analysis by capillary puncture comprising a needle having an exterior surface that is adapted to puncture skin and a removable coating on said exterior surface wherein the portion of said coating that comes in contact with a puncture site obtained by capillary puncture with said needle is transferred from said needle to said puncture site, said coating comprising a composition which inhibits contact activation of the drop of blood at said puncture site.
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Accused Products
Abstract
A piercing instrument (12) for obtaining a non-activated drop of blood (B) by capillary puncture is formed by depositing a coating agent (20) on the exterior surface of the piercing instrument (12). The coating agent comprises compounds that inhibit the activation of blood.
92 Citations
30 Claims
- 1. A lancet for obtaining a drop of blood for analysis by capillary puncture comprising a needle having an exterior surface that is adapted to puncture skin and a removable coating on said exterior surface wherein the portion of said coating that comes in contact with a puncture site obtained by capillary puncture with said needle is transferred from said needle to said puncture site, said coating comprising a composition which inhibits contact activation of the drop of blood at said puncture site.
- 4. An apparatus for obtaining blood samples by capillary puncture comprising a lancet and a removable coating on the surface of said lancet wherein the portion of said coating that comes in contact with a puncture site obtained by capillary puncture with said lancet is transferred from said lancet to said puncture site, said coating including a blood platelet inhibitor, a serine protease inhibitor, and a monoclonal antibody to thromboplastin.
- 8. An apparatus for inhibiting contact activation of blood, comprising an instrument adapted to puncture a bodily tissue and having an exterior surface coated with a removable composition, wherein the portion of said coating that comes in contact with a puncture site obtained by capillary puncture with said instrument is transferred from said instrument to said puncture site, said composition comprising one or more compounds that specifically inhibit one or more blood activation mechanisms at the puncture site.
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17. A method of obtaining a drop of blood for analysis, comprising the steps of:
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coating an outside surface of a lancet with a removable composition that inhibits contact activation of the drop of blood; and
puncturing a bodily tissue with said outside surface of said lancet to obtain the drop of blood, wherein the portion of said composition that comes in contact with said bodily tissue is transferred from said lancet to said puncture site. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24)
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25. A method for obtaining a non-activated drop of blood comprising:
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coating a surface of an instrument with a removable composition comprising a serine protease inhibitor, a blood platelet inhibitor, and a monoclonal antibody to thromboplastin; and
puncturing a bodily tissue with said instrument, thereby transferring the portion of said composition that comes in contact with the puncture site from said instrument to the puncture site wherein said serine protease inhibitor, said blood platelet inhibitor, and said monoclonal antibody inhibit one or more blood activation mechanisms.
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- 26. An improved lancet for obtaining a drop of blood for analysis by capillary puncture of a bodily tissue, wherein the improvement comprises said lancet having a removable coating thereon of a composition which precludes contact activation, platelet activation, and fibrinolysis of the blood sample, wherein the portion of said coating that comes in contact with a bodily tissue is transferred from said lancet to the puncture site.
Specification