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Laundry detergent and/or fabric care compositions comprising a modified enzyme

  • US 6,468,955 B1
  • Filed: 11/01/2000
  • Issued: 10/22/2002
  • Est. Priority Date: 05/01/1998
  • Status: Expired due to Fees
First Claim
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1. A modified enzyme comprising a catalytically active amino acid sequence of an enzyme, linked via a non-amino acid linking region, to an amino acid sequence comprising a cellulose binding domain wherein said catalytically active amino acid sequence derives from an enzyme selected from lipase, protease, amylase, cellulase, glycosyltransferase, xylanase, hexosaminidase, mannanase, oxidoreductase and mixtures thereof;

  • further wherein said non-amino acid linking region is selected from the group consisting of;

    polyethylene glycol derivatives, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide, N-ethyl-5-phenylisaoxolium-3-sulphonate, 1-cyclohexyl-3(2morpholineothyl)carbodide metho-p-toluene sulphonate, N-ethoxycarbonyl-2-ethoxy 1,2, dihydroquinoline, glutaraldehyde, crosslinkers, PEG(NPC)2, (NH2)2-PEG, t-BOC-NH-PEG-NH2, MAL-PEG-NHS, VS-PEG-NHS, Sulfo-KMUS compounds and mixtures thereof and further wherein said cellulose binding domain is selected from the group consisting of;

    CBD CenC, CenA, Cex from Cellulomonas fimi, CDB CBHI from Trichoderma reesei, CBD Cellulose from Clostridium cellulovorans, CBD E3 from Thermonospora fusca, CBD-dimer from Clostridium stecorarium XynA, CBD from Bacillius agaradherens, CBD family 45 from Humicola insolens and mixtures thereof.

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