Reconstitution device and method of use

• US 6,474,375 B2
• Filed: 02/02/2001
• Issued: 11/05/2002
• Est. Priority Date: 02/02/2001
• Status: Expired due to Fees

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Laas, Terry E., Spero, Richard, Hagmann, Adam
• Primary Examiner(s): Douglas, Steven O.
• Application Number:
  US09/776,351
• Publication Number:
  US 20020104584A1
• Time in Patent Office: 641 Days
• Field of Search: 141/329, 141/330, 141/59, 141/65, 141/66, 141/19, 141/9, 141/100, 604/411-416
• US Class Current: 141/329
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2072 for internal venting
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096

Abstract

A method and apparatus for reconstituting a multiple component material is disclosed. More particularly, the present invention discloses an apparatus utilizing an operator controllable pressurization device to generate a pressure differential between two receptacles attached to the device. The receptacles may contain individual components of a multiple component material, and may include liquid-liquid or liquid-solid compounds. The apparatus includes a material transfer lumen attachable to a first and second component receptacle. A pressurization lumen is connected to one of the component receptacles to facilitate material transfer. One embodiment of the present invention utilizes a negative pressure differential created in the second receptacle to facilitate transfer. In another embodiment, a positive pressure is created in the first receptacle to force material transfer between the two receptacles.

Claims

1. A reconstitution device, comprising:

a first receptacle receiver having a first component cannula disposed therein, said first component cannula having a material flow lumen therethrough and having at least a first transfer port formed thereon and in communication with said material flow lumen, said first component cannula having a pointed tip;

a second receptacle receiver connected to said first receptacle receiver, said second receptacle receiver having a second component cannula disposed therein and wherein said material flow lumen traverses through said second component cannula, said second component cannula having a second transfer port formed thereon and in communication with said material flow lumen, said second component cannula having a second pointed tip;

a pressure lumen formed within at least one of said first component cannula and said second component cannula;

a pressure port formed on at least one of said first component cannula and said second component cannula and in fluid communication with pressure lumen; and

a user-controllable source of pressure in fluid communication with said pressure lumen.

2. The reconstitution device of claim 1, wherein the pressure source is a source of positive pressure.

3. The reconstitution device of claim 2, further comprising a chamber between said first receptacle receiver and said second receptacle receiver and wherein said pressure source comprises a piston residing in said chamber and said pressure lumen is in fluid communication with said chamber.

4. The reconstitution device of claim 3, wherein said chamber is capable of compression, thereby introducing a positive pressure to said first receptacle through said pressure lumen.

5. The reconstitution device of claim 1, wherein the pressure source is a source of negative pressure.

6. The reconstitution device of claim 5, wherein the negative pressure source is a syringe.

7. The reconstitution device of claim 5, wherein the negative pressure source is an external vacuum source.

8. The reconstitution device of claim 1, wherein the pressure source is a source of positive pressure created in a first receptacle and a source of negative pressure created in a second receptacle.

9. A reconstitution device, comprising:

a first receptacle receiver having a first component cannula disposed therein, said first component cannula having a material flow lumen therethrough and having at least a first transfer port formed thereon and in communication with said material flow lumen, said first component cannula having a pointed tip;

a second receptacle receiver connected to said first receptacle receiver, said second receptacle receiver having a second component cannula disposed therein and wherein said material flow lumen traverses through said second component cannula, said second component cannula having a second transfer port formed thereon and in communication with said material flow lumen, said second component cannula having a second pointed tip;

a pressure lumen formed within said second component cannula;

a pressure port formed on said second component cannula and in fluid communication with pressure lumen; and

a user-controllable source of pressure in fluid communication with said pressure lumen.

10. The reconstitution device of claim 9, wherein said pressure source is a source of negative pressure.

11. The reconstitution device of claim 10, wherein the negative pressure source is a syringe connected to the device through an externally accessible orifice in communication with said pressure lumen.

12. The reconstitution device of claim 9, wherein said first receptacle receiver comprises a first receptacle stop and at least first receptacle support member attached thereto.

13. The reconstitution device of claim 12, wherein at least one receptacle locking member is positioned on said first receptacle support member.

14. A reconstitution device, comprising:

a first receptacle receiver having a first component cannula disposed therein, said first component cannula having a material flow lumen therethrough and having at least a first transfer port formed thereon and in communication with said material flow lumen, said first component cannula having a pointed tip;

a second receptacle receiver connected to said first receptacle receiver, said second receptacle receiver having a second component cannula disposed therein and wherein said material flow lumen traverses through said second component cannula, said second component cannula having a second transfer port formed thereon and in communication with said material flow lumen, said second component cannula having a second pointed tip;

a pressure lumen formed within said first component cannula;

a pressure port formed on said first component cannula and in fluid communication with pressure lumen; and

a user-controllable source of pressure in fluid communication with said pressure lumen.

15. The reconstitution device of claim 14, wherein the pressure source is a source of positive pressure.

16. The reconstitution device of claim 15, further comprising a chamber between said first receptacle receiver and said second receptacle receiver and wherein said pressure source comprises a piston residing in said chamber and said pressure lumen is in fluid communication with said chamber.

17. The reconstitution device of claim 16, wherein said chamber is capable of compression, thereby introducing a positive pressure to said first receptacle through said pressure lumen.