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Method for determining the reliability of fMRI parameters

  • US 6,477,399 B2
  • Filed: 03/29/2001
  • Issued: 11/05/2002
  • Est. Priority Date: 03/29/2000
  • Status: Active Grant
First Claim
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1. A method for producing a functional magnetic resonance image (fMRI) of a subject'"'"'s brain using a magnetic resonance imaging (MRI) system, the steps comprising:

  • a) operating the MRI system to perform a series of pulse sequences that acquire a series of NMR k-space data arrays over a period of time, during which the subject'"'"'s brain is caused to function in a preselected temporal pattern;

    b) producing a time course MRI image data set of time domain voxel vectors from the series of k-space arrays, in which each time domain voxel vector is a set of data which indicates the NMR signal during said period of time from a region of the brain;

    c) calculating an fMRI parameter from data in each time domain voxel vector;

    d) calculating a confidence level indicator for each voxel vector using a technique in which the fMRI parameter is recalculated a plurality of times with different truncated subsets of data in the voxel vector;

    e) producing the fMRI image using the calculated fMRI parameters and their corresponding confidence level indicators.

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