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Substituted porphyrins

  • US 6,479,477 B1
  • Filed: 04/23/1999
  • Issued: 11/12/2002
  • Est. Priority Date: 04/24/1998
  • Status: Expired due to Term
First Claim
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1. A compound of Formula I or Formula II;

  • embedded imageor pharmaceutically acceptable salt thereof, whereinR1 and R3 are independently;



    CO2C1-4 alkyl;

    or —

    CO2(CH2)nCX3, wherein X is halogen and n=1 to 3;

    R2 is;



    H —

    C1-4alkyl —

    COOH —

    CO2C1-4 alkyl, —

    CO2(CH2)nCX3, wherein X is halogen and n=1 to 3, —

    CON(CH3)2, or —

    CX3, wherein X is halogen; and

    R4 is;



    H, —

    C1-4 alkyl —

    COOH, —

    CO2C1-4 alkyl, —

    CO2(CH2)nCX3, wherein X is halogen and n=1 to 3, —

    CON(CH3)2, or —

    CX3, wherein X is halogen, and each A is, independently, hydrogen or halogen, wherein when said compound is of Formula II, M is a metal selected from the group consisting of manganese, iron, copper, cobalt, nickel and zinc and Z

    is a counterion.

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