Cardiac arrhythmia detector using ECG waveform-factor and its irregularity

• US 6,480,734 B1
• Filed: 06/30/2000
• Issued: 11/12/2002
• Est. Priority Date: 06/30/2000
• Status: Expired due to Term

• Current Assignee: Zoll Medical Corporation (Asahi Kasei Corporation)
• Original Assignee: Cardiac Science Operating Company (Cardica Incorporated)
• Inventors: Zhang, Xu-Sheng, Lin, Dongping
• Primary Examiner(s): Evanisko, George R.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/609,558
• Time in Patent Office: 865 Days
• Field of Search: 600/516, 600/517, 600/518, 607/4, 607/5, 607/14, 607/25, 607/9
• US Class Current: 600/518
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/3904 External heart defibrillators [EHD]
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A cardiac monitor is provided that monitors the condition of the heart of a cardiac patient and generates signals indicating one of several conditions, such as supraventricular tachycardia, ventricular tachycardia and ventricular fibrillation. In order to generate these signals, the ECG from the patient is analyzed to determine a cardiac interval and heart rate, as well as a waveform factor and a waveform factor irregularity. The waveform factor is derived from the average of the ECG amplitudes during a cardiac interval and the peak value of the ECG during the same interval. Preferably, a running average is calculated over several intervals. This waveform factor is then used to detect shockable ventricular arrhythmia. The waveform factor irregularity is indicative of the variability of the waveform factor and is used to differentiate between ventricular tachycardia and ventricular defibrillation.

Claims

1. A cardiac monitor for determining the cardiac condition of a patient comprising:

a sensor that senses the intrinsic activity of a patient'"'"'s heart and generates a corresponding sensed signal;

an interval detector that detects an interval associated with a cardiac cycle based on said sensed signal;

a waveform factor detector that detects a waveform factor from said sensed signal, said waveform factor being a function of a ratio of a mean value of said signal during said cardiac cycle and a peak value of said signal during said interval; and

a first comparator that compares said waveform factor to a threshold and generates a corresponding for first output indicative of the patient'"'"'s cardiac condition.

2. The cardiac monitor of claim 1 further comprising a waveform factor irregularity detector that detects a sudden change in said waveform factor and generates a corresponding second output.

3. The cardiac monitor of claim 2 further comprising a second comparator that compares said second output to a second threshold, said second comparator generating a comparator output indicative of one of ventricular tachycardia and ventricular fibrillation based on said comparator output.

4. The cardiac monitor of claim 2 wherein said waveform factor irregularity detector further includes an averager that averages a waveform factor irregularity over several cardiac cycles to generate an irregularity average indicative of one of a tachycardiac and ventricular fibrillation condition.

5. The cardiac monitor of claim 1 wherein said cardiac monitor is external.

6. The cardiac monitor of claim 1 wherein said cardiac monitor is implantable.

7. The cardiac monitor of claim 1 wherein said cardiac monitor is incorporated into an internal defibrillator.

8. The cardiac monitor of claim 1 wherein said cardiac monitor is incorporated into an external defibrillator.

9. The cardiac monitor of claim 1 wherein said sensor signal is an ECG.

10. The cardiac monitor of claim 1 wherein said waveform factor detector detects a plurality of instant waveform factors, each instant waveform factor being derived from the ratio of between said mean value and said peak value.

11. The cardiac monitor of claim 10 wherein said waveform factor detector detects said instant waveform factors based on said mean value, wherein said mean value is determined from an area under said sensed signal and a current R-wave peak value of said sensed signal.

12. The cardiac monitor of claim 10 wherein said waveform factor detector determines said waveform factor by averaging said plurality of instant waveform factors.

13. The cardiac monitor of claim 2 wherein said wave form factor irregularity detector generates a waveform factor irregularity based on a difference between two consecutive waveform factors.

14. A cardiac therapy device adapted to selectively provide shock therapy to a patient, comprising:

a sensor adapted to detect intrinsic activity in the patient'"'"'s heart and to generate a corresponding sensed signal;

a pulse generator adapted to generate therapy pulses in response to control signals;

a monitor adapted to classify a cardiac condition and to generate a corresponding heart condition signal; and

a controller adapted to receive said heart condition signal and to generate in response said control signals;

wherein said monitor includes;

an interval detector that detects an interval associated with a cardiac cycle based on said sensed signal;

a waveform factor detector that detects a waveform factor from said sensed signal, said waveform factor being a function of a ratio of a mean value of said sensed signal during said cardiac cycle and a peak value of said sensed signal during said interval; and

a first comparator that compares said waveform factor to a threshold and generates a corresponding first output indicative of the patient'"'"'s cardiac condition.

15. The device of claim 14 wherein said monitor further comprises a waveform factor irregularity detector that detects a sudden change in said waveform factor and generates a corresponding second output.

16. The device of claim 15 wherein said monitor further comprises a second comparator that compares said second output to a second threshold, said second comparator generating a comparator output indicative of one of ventricular tachycardia and ventricular fibrillation based on said comparator output.

17. The device of claim 15 wherein said waveform irregularity detector further includes an averager that averages said waveform irregularity over several cardiac cycles to generate an irregularity average indicative of one of a tachycardiac and ventricular fibrillation condition.

18. The device of claim 14 wherein said device is external.

19. The device of claim 14 wherein said device is implantable.

20. The device of claim 14 wherein said sensed signal is an ECG.