Non-or minimally invasive monitoring methods using particle delivery methods
First Claim
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1. A measured quanitity of a powder composition comprising sampling particles, said powder composition comprising size-selected particles of an inert material selected from the group consisting of sugars, soluble or dissolvable polymers, starch, TiO2, calcium carbonate, phosphate salts, lactic acid and hydroxy apatite.
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Abstract
Methods for sampling an analyte present in a biological system are provided. The methods entail use of particle delivery methods to obtain a sample of an analyte of interest from the system.
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Citations
27 Claims
- 1. A measured quanitity of a powder composition comprising sampling particles, said powder composition comprising size-selected particles of an inert material selected from the group consisting of sugars, soluble or dissolvable polymers, starch, TiO2, calcium carbonate, phosphate salts, lactic acid and hydroxy apatite.
- 11. Sampling particles, comprising particles of an inert material coated with a locally active agent.
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18. A method for sampling an analyte present beneath a target skin or mucosal surface of an individual, said method comprising:
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(a) creating passages in the target surface sufficient to allow said analyte to flow, exude or otherwise pass from beneath the target surface to the target surface; and
(b) contacting the target surface with a sensing apparatus that detects the presence or amount of said analyte. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27)
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Specification