X-ray target assembly and radiation therapy systems and methods

• US 6,487,274 B2
• Filed: 01/29/2001
• Issued: 11/26/2002
• Est. Priority Date: 01/29/2001
• Status: Expired due to Term

• Current Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Original Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Inventors: Bertsche, Kirk Joseph
• Primary Examiner(s): Porta, David P.
• Assistant Examiner(s): Ho, Allen C.
• Application Number:
  US09/772,435
• Publication Number:
  US 20020101958A1
• Time in Patent Office: 666 Days
• Field of Search: 378/98.9, 378/124, 378/143, 378/144, 378/65, 378/98.11
• US Class Current: 378/143
• CPC Class Codes: A61N 2005/1085 characterised by the type of particles applied to the patient
• CPC Class Codes: A61N 5/10 X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy A61N5/01 takes precedence
• CPC Class Codes: H01J 2235/081 Target material
• CPC Class Codes: H01J 35/13 Active cooling, e.g. fluid flow, heat pipes

Abstract

A multi-region target that is configured to selectively generate two different energy distributions when exposed to an excitation electron beam is described. The multi-region target includes multiple regions with different x-ray generating characteristics. Thus, the interaction between an excitation electron beam and the target generates an x-ray beam with an energy distribution that depends upon which target region is exposed to the excitation electron beam. The different x-ray spectra may be used to produce an enhanced contrast x-ray image. A method of detecting the rotational position of the multi-region target based upon the contrast level of the resulting images also is described.

Claims

1. A target assembly, comprising:

a target having

a surface exposed to receive an excitation beam along an expected beam path including at least first and second non-overlapping beam path portions,

a first region operable to generate substantial x-radiation characterized by a first energy distribution in response to an excitation beam incident upon the exposed surface along the first beam path portion, and

a second region operable to generate substantial x-radiation characterized by a second energy distribution different from the first energy distribution in response to an excitation beam incident upon the exposed surface along the second beam path portion; and

a cooling mechanism coupled to the first and second regions of the target.

2. The target assembly of claim 1, wherein the first region comprises a first x-ray generating material composition, and the second region comprises a second x-ray generating material composition that is different from the first material composition.

3. The target assembly of claim 2, wherein the first x-ray generating material composition is characterized by a higher atomic number than the second x-ray generating material composition.

4. The target assembly of claim 3, wherein the first x-ray generating material composition includes a material with an atomic number of 72 or higher, and the second x-ray generating material composition includes a material with an atomic number of 30 or lower.

5. The target assembly of claim 3, wherein the relatively high atomic number material is tungsten or tantalum or gold, and the relatively low atomic number material is aluminum, beryllium, carbon or aluminum oxide.

6. The target assembly of claim 3, wherein the first region is larger than the second region.

7. The target assembly of claim 1, wherein the target is substantially disk-shaped and the first and second regions correspond to respective sectors of the substantially disk-shaped target.

8. The target assembly of claim 1, wherein the target is substantially disk-shaped, the second region corresponds to one or more peripheral portions of the substantially disk-shaped target, and the first region corresponds to remaining portions of the substantially disk-shaped target.

9. A target assembly, comprising:

a target having

an exposed surface,

a first region comprising a first x-ray generating characteristic, and

a second region laterally displaced from the first region with respect to an excitation beam incident upon the exposed surface and comprising a second x-ray generating characteristic that is different from the first x-ray generating characteristic; and

a cooling mechanism coupled to the first and second regions of the target, wherein the cooling mechanism includes a target holder configured to support the target for rotation and to expose the target to a cooling fluid stream, whereby the target rotates about an axis of rotation upon exposure to the cooling fluid stream.

10. A radiation therapy system, comprising:

a source of an electron beam; and

a target positioned to intercept the electron beam and having

a surface exposed to receive an excitation beam along an expected beam path including at least first and second non-overlapping beam path portions,

a first region operable to generate substantial x-radiation characterized by a first energy distribution in response to an excitation beam incident upon the exposed surface along the first beam path portion, and

a second region operable to generate substantial x-radiation characterized by a second energy distribution different from the first energy distribution in response to an excitation beam incident upon the exposed surface along the second beam path portion.

11. The target assembly of claim 10, wherein the first region comprises a first x-ray generating material composition, and the second region comprises a second x-ray generating material composition that is different from the first material composition.

12. The radiation therapy system of claim 11, wherein the first x-ray generating material composition is characterized by a higher atomic number than the second x-ray generating material composition.

13. The radiation therapy system of claim 12, wherein the first region is larger than the second region.

14. The radiation therapy system of claim 10, further comprising a computer configured to identify images produced from x-rays generated by the first target region and to identify images produced from x-rays generated by the second target region.

15. The radiation therapy system of claim 10, wherein the source is configured to produce an electron beam with an energy of 1 MeV or greater.

16. A radiation therapy system, comprising:

a source of an electron beam;

a target positioned to intercept the electron beam and having an exposed surface, a first region comprising a first x-ray generating characteristic, and a second region laterally displaced from the first region with respect to an electron beam incident upon the exposed surface and comprising a second x-ray generating characteristic that is different from the first x-ray generating characteristic; and

a computer configured to identify images produced from x-rays generated by the first target region and to identify images produced from x-rays generated by the second target region, wherein the computer is configured to identify images based upon image contrast.

17. The radiation therapy system of claim 16, wherein the computer is configured to produce an enhanced image by combining image data produced from x-rays generated by the second target region with image data produced from x-rays generated by the first target region.

18. A radiation therapy method, comprising:

generating an electron beam; and

positioning to intercept the electron beam a target having

a surface exposed to receive an excitation beam along an expected beam path including at least first and second non-overlapping beam path portions,

a first region operable to generate substantial x-radiation characterized by a first energy distribution in response to an excitation beam incident upon the exposed surface along the first beam path portion, and

a second region operable to generate substantial x-radiation characterized by a second energy distribution different from the first energy distribution in response to an excitation beam incident upon the exposed surface along the second beam path portion.

19. The radiation therapy method of claim 18, further comprising:

generating images from x-rays generated by exposing the target to the electron beam;

identifying images produced from x-rays generated by the first target region; and

identifying images produced from x-rays generated by the second target region.

20. The radiation therapy method of claim 18, further comprising producing an enhanced image by combining image data produced from x-rays generated by the second target region with image data produced from x-rays generated by the first target region.

21. The radiation therapy method of claim 18, wherein an electron beam of 1 MeV or greater is produced.

22. A radiation therapy method, comprising:

generating an electron beam;

positioning to intercept the electron beam a target having an exposed surface, a first region comprising a first x-ray generating characteristic, and a second region laterally displaced from the first region with respect to an electron beam incident upon the exposed surface and comprising a second x-ray generating characteristic that is different from the first x-ray generating characteristic;

generating images from x-rays generated by exposing the target to the electron beam;

identifying images produced from x-rays generated by the first target region; and

identifying images produced from x-rays generated by the second target region,

wherein images are identified based upon image contrast.