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Use of targeted glycemic profiles in the calibration of a noninvasive blood glucose monitor

  • US 6,487,429 B2
  • Filed: 01/18/2001
  • Issued: 11/26/2002
  • Est. Priority Date: 05/30/2000
  • Status: Expired due to Fees
First Claim
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1. A method of calibrating a non-invasive blood glucose measurement instrument to an individual, said method comprising the steps of:

  • providing one or more targeted glycemic profiles;

    manipulating said individual'"'"'s blood glucose level such that patterns of said profiles are reproduced by subject'"'"'s own glycemic profile;

    performing reference blood glucose measurements at predetermined intervals;

    gathering non-invasive spectral measurements with said non-invasive glucose measurement instrument at said predetermined intervals; and

    generating a calibration that correlates said reference measurements and said spectral samples, such that an algorithm predicts a blood glucose level from a new spectral sample.

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