Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias

• US 6,487,443 B2
• Filed: 03/28/2001
• Issued: 11/26/2002
• Est. Priority Date: 03/30/1995
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Kaemmerer, William F., Brown, Mark L., Olson, Walter H.
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US09/819,433
• Publication Number:
  US 20010034538A1
• Time in Patent Office: 608 Days
• Field of Search: 607/4, 607/5, 607/9, 607/14, 600/515, 600/518
• US Class Current: 600/518
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/29 for permanent or long-term implantation
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

An implantable antiarrhythmia device which detects and classifies arrhythmias of the human heart, and delivers appropriate therapy. The device employs a method of arrhythmia classification based on a set of prioritized rules, each of the rules defining a plurality of criteria based upon characteristics of sensed depolarizations of heart tissue, each rule being met when the criteria associated with the rule are met. Some rules, when met, trigger delivery of antiarrhythmia therapy. Other rules, when met, inhibit delivery of antiarrhythmia therapy. The rules may be met simultaneously, and if so, the highest priority rule governs the behavior of the device.

Claims

1. A rule-based cardiac arrhythmia detection software system, comprising:

a set of parameters defining a plurality of hierarchical cardiac event pattern code rules, each of said pattern code rules prescribing criteria corresponding to a specific type of cardiac rhythm;

an instruction set for storing information regarding each occurrence of a cardiac event according to type;

an instruction set that computes time-based features for each occurrence of the cardiac event;

an instruction set that computes a pattern code for each occurrence of the cardiac event which is based at least in part on the computed time-based features;

an instruction set that computes counts of adherence based on the computed pattern code;

an instruction set that applies the pattern code rules to the computed counts of adherence to determine a positive or a negative compliance status with any of said pattern code rules;

an instruction set that selects a highest priority rule that is determined to have a positive compliance status; and

an instruction set that provides an output indication of the specific type of cardiac rhythm corresponding to the selected highest priority rule.

2. A system of claim 1 wherein the cardiac event comprises:

an atrial event and a ventricular event, which is distinguishable from the atrial event, according to said pattern code rules.

3. A system of claim 2 wherein the time-based features for the cardiac events comprise an R—

R interval, an R-P interval, a P—

P interval and a P-R interval.

4. A system of claim 3, wherein the instruction set that computes a pattern code comprises an instruction set for timing each of at least one atrial event and at timing of at least one ventricular event during a preceding two of said R—

R interval.

5. A system of claim 4 wherein each of the preceding two of said R—

R interval comprises at least four discrete temporal zones.

6. A system of claim 5 wherein the instruction set that computes a pattern code assigns each said R—

R interval a beat code based on each atrial event that occurs during the R—

R interval and based on the location of the atrial event relative to the at least four discrete temporal zones.

7. A system of claim 6 wherein the set of parameters defining said pattern code rules comprises a look-up table correlating the beat code to a one of the specific type of cardiac rhythm.

8. A system of claim 6 further comprising an instruction set that stores the computed cardiac event pattern codes.

9. A system of claim 5 wherein the instruction set that computes a pattern code assigns each one of the preceding two said R—

R interval a beat code, said beat code based upon;

the number of at least one atrial event during the R—

R interval,

a duration of the P-R interval associated with the R—

R interval, and

a duration of the R-P interval associated with the R—

R interval.

10. A system of claim 9,

wherein the number of at least one atrial event during the R—

R interval constitutes a P count,

wherein the R-P interval is the time in milliseconds from the beginning of a ventricular event in the R—

R interval to a first of the at least one atrial event within the R—

R interval, and

wherein the P-R interval is the time in milliseconds from a last one of said at least one atrial event in the R—

R interval to the first of the at least one atrial event within the R—

R interval to a concluding ventricular event in the R—

R interval.

11. A system of claim 10 wherein a beat count of between zero to nine is generated by the instruction set that computes time-based features based on the P count and a recorded event time of the at least one atrial event.

12. A system of claim 2, further comprising:

an instruction set that counts a number of uninterrupted atrial events after a prior ventricular event and that then counts a number of uninterrupted ventricular events after a last atrial event, all according to said pattern code rules.

13. A system of claim 1 wherein the cardiac event pattern code rules specify said specific type of cardiac rhythm including:

a ventricular fibrillation type, a fast ventricular tachycardia type, a ventricular tachycardia type, a simultaneous ventricular and supraventricular tachycardia type, an atrial fibrillation type, an atrial flutter type, a sinus tachycardia type, an AV nodal re-entrant tachycardia type, and a normal sinus rhythm type.