Methods and apparatus for transpericardial left atrial appendage closure

• US 6,488,689 B1
• Filed: 05/20/1999
• Issued: 12/03/2002
• Est. Priority Date: 05/20/1999
• Status: Expired due to Term

• Current Assignee: SentreHeart, LLC (Atricure, Inc.)
• Original Assignee: Aaron V. Kaplan
• Inventors: Kaplan, Aaron V., Bajor, Jordan T.
• Primary Examiner(s): Recla, Henry J.
• Assistant Examiner(s): Ho, Tan-Uyen T.
• Application Number:
  US09/315,601
• Time in Patent Office: 1,293 Days
• Field of Search: 606/139, 606/194, 604/49, 604/175, 604/96, 128/898
• US Class Current: 606/139
• CPC Class Codes: A61B 17/10 for applying or removing wound clamps, e.g. containing only one clamp or staple A61B17/076 takes precedence; containing multiple wound clamps A61B17/068; Wound clamp magazines containers, packaging elements or packages specially adapted for particular articles or with special means for dispensing contents B65D83/00, B65D85/00
• CPC Class Codes: A61B 17/12 for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord specially adapted for vas deferens or fallopian tubes A61F6/20; materials for ligaturing blood vessels A61L17/00
• CPC Class Codes: A61B 17/12013 for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/320048 Balloon dissectors

Abstract

Methods and apparatus for closing a left atrial appendage are described. The methods rely on introducing a closure tool from a location beneath the rib cage, over an epicardial surface, and to the exterior of the left atrial appendage. The closure device may then be used to close the left atrial appendage, preferably at its base, by any one of a variety of techniques. A specific technique using graspers and a closing loop is illustrated.

Claims

1. A method for closing a left atrial appendage of a patient'"'"'s heart, said method comprising:

making an incision between a costal cartilage and a xiphoid of the patient;

placing an access sheath through the incision into a pericardial space;

positioning a closure instrument through the access sheath into the pericardial space beneath the rib cage, over an epicardial surface, and adjacent to the left atrial appendage; and

closing the left atrial appendage using the closure instrument.

2. A method as in claim 1, wherein positioning further comprises advancing a distal end of the closure instrument through the sheath, into the pericardial space, and over an epicardial surface to an atrioventricular groove of the heart.

3. A method as in claim 2, wherein closing comprises looping, suturing, stapling, clipping, riveting, clamping, or fusing the left atrial appendage at a neck region thereof.

4. A method as in claim 3, wherein closing further comprises grasping the left atrial appendage prior to closing the neck region thereof.

5. A method as in claim 1, wherein the method is performed while the patient'"'"'s heart is beating.

6. A method as in claim 5, wherein the method is performed while both lungs of the patient remain inflated.

7. A method as in claim 6, wherein the method is performed while the patient is under a local anesthetic.

9. A method as in claim 1, further comprising separating the parietal pericardium from the visceral pericardium near left atrial appendage prior to closing the left atrial appendage to create a space over the atrial appendage.

10. A method as in claim 9, further comprising viewing the atrial appendage through the space.

8. An improved method for closing a left atrial appendage of a heart, said method being of the type wherein a closure element is placed over an exterior of the appendage while the patient'"'"'s chest remains closed, wherein the improvement comprises advancing the closure element from beneath the rib cage over an epicardial surface to the exterior of the left atrial appendage prior to placing the closure element over the left atrial appendage.

11. A method for closing a left atrial appendage of a patient'"'"'s heart, said method comprising:

positioning a closure instrument through a percutaneous passage into a pericardial space beneath the rib cage, over an epicardial surface, and adjacent to the left atrial appendage, without passing through the pleural space; and

closing the left atrial appendage using the closure instrument.

12. A method as in claim 11, wherein positioning comprises making an incision between a costal cartilage and a xiphoid of the patient and placing an access sheath through the incision into the pericardial space.

13. A method as in claim 12, wherein positioning further comprises advancing a distal end of the closure instrument through the sheath, into the pericardial space, and over an epicardial surface to an atrioventricular groove of the heart.

14. A method as in claim 13, wherein closing comprises looping, suturing, stapling, clipping, riveting, clamping, or fusing the left atrial appendage at a neck region thereof.

15. A method as in claim 14, wherein closing further comprises grasping the left atrial appendage prior to closing the neck region thereof.

16. A method as in claim 11, wherein the method is performed while the patient'"'"'s heart is beating.

17. A method as in claim 16, wherein the method is performed while both lungs of the patient remain inflated.

18. A method as in claim 17, wherein the method is performed while the patient is under a local anesthetic.

19. A method as in claim 11, further comprising separating the parietal pericardium from the visceral pericardium near the left atrial appendage prior to closing the left atrial appendage to create a space over the atrial appendage.

20. A method as in claim 19, further comprising viewing the atrial appendage through the space.

21. A method for closing a left atrial appendage of a patient'"'"'s heart, said method comprising:

positioning a closure instrument through a percutaneous passage into a pericardial space beneath the rib cage, over an epicardial surface, and adjacent to the left atrial appendage, while both lungs of the patient remain inflated; and

closing the left atrial appendage using the closure instrument.

22. A method as in claim 21, wherein positioning comprises making an incision between a costal cartilage and a xiphoid of the patient and placing an access sheath through the incision into the pericardial space.

23. A method as in claim 22, wherein positioning further comprises advancing a distal end of the closure instrument through the sheath, into the pericardial space, and over an epicardial surface to an atrioventricular groove of the heart.

24. A method as in claim 23, wherein closing comprises looping, suturing, stapling, clipping, riveting, clamping, or fusing the left atrial appendage at a neck region thereof.

25. A method as in claim 24, wherein closing further comprises grasping the left atrial appendage prior to closing the neck region thereof.

26. A method as in claim 21, wherein the method is performed while the patient'"'"'s heart is beating.

27. A method as in claim 21, wherein the method is performed while the patient is under a local anesthetic.

28. A method as in claim 21, further comprising separating the parietal pericardium from the visceral pericardium near the left atrial appendage prior to closing the left atrial appendage to create a space over the atrial appendage.

29. A method as in claim 28, further comprising viewing the atrial appendage through the space.

30. A method for closing a left atrial appendage of a patient'"'"'s heart, said method comprising:

inserting a closure instrument through a percutaneous passage;

introducing the closure instrument into a pericardial space by passing the closure instrument beneath the rib cage, over an epicardial surface, and adjacent to the left atrial appendage, without passing through the pleural space; and

closing the left atrial appendage using the closure instrument.

31. A method as in claim 30, wherein inserting comprises making an incision between a costal cartilage and a xiphoid of the patient and placing an access sheath through the incision into the pericardial space.

32. A method as in claim 31, wherein introducing further comprises advancing a distal end of the closure instrument through the sheath, into the pericardial space, and over an epicardial surface to an atrioventricular groove of the heart.

33. A method as in claim 32, wherein closing comprises looping, suturing, stapling, clipping, riveting, clamping, or fusing the left atrial appendage at a neck region thereof.

34. A method as in claim 33, wherein closing further comprises grasping the left atrial appendage prior to closing the neck region thereof.

35. A method as in claim 30, wherein the method is performed while the patient'"'"'s heart is beating.

36. A method as in claim 35, wherein the method is performed while both lungs of the patient remain inflated.

37. A method as in claim 36, wherein the method is performed while the patient is under a local anesthetic.

38. A method as in claim 30, further comprising separating the parietal pericardium from the visceral pericardium near the left atrial appendage prior to closing the left atrial appendage to create a space over the atrial appendage.

39. A method as in claim 38, further comprising viewing the atrial appendage through the space.