Microfluidic devices and systems incorporating cover layers
First Claim
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1. A microfluidic apparatus, comprising:
- a device comprising a body structure, wherein disposed within said body structure is at least one microscale channel network, said microscale channel network in fluid communication with at least one reservoir;
said at least one reservoir comprising a rim disposed circumferentially around it, said rim and a portion of an internal surface of said reservoir comprising a conductive coating;
a cover layer mated with said device, wherein said cover layer comprises at least one aperture, said at least one aperture aligned with said at least one reservoir; and
at least one semi-permeable membrane portion, said membrane portion disposed over said at least one aperture.
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Abstract
The present invention provides microfluidic devices that comprise a body structure comprising at least a first microscale channel network disposed therein. The body structure has a plurality of ports disposed in the body structure, where each port is in fluid communication with one or more channels in the first channel network. The devices also include a cover layer comprising a plurality of apertures disposed through the cover layer. The cover layer is mated with the body structure whereby each of the apertures is aligned with a separate one of the plurality of ports.
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10 Claims
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1. A microfluidic apparatus, comprising:
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a device comprising a body structure, wherein disposed within said body structure is at least one microscale channel network, said microscale channel network in fluid communication with at least one reservoir;
said at least one reservoir comprising a rim disposed circumferentially around it, said rim and a portion of an internal surface of said reservoir comprising a conductive coating;
a cover layer mated with said device, wherein said cover layer comprises at least one aperture, said at least one aperture aligned with said at least one reservoir; and
at least one semi-permeable membrane portion, said membrane portion disposed over said at least one aperture. - View Dependent Claims (2, 3, 5, 6, 7, 8, 9, 10)
a microfluidic device of claim 1, and a controller configured to received the microfluidic device;
a detector comprising an optical detection system, said detector interfaced with said controller; and
a material transport system operably interfaced with the microfluidic device.
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8. The microfluidic system of claim 7, wherein said controller further comprises an environmental control system.
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9. The microfluidic system of claim 8, wherein said environmental control system is selected from one or more of:
- a thermal control system, a humidity control system or a light control system.
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10. The microfluidic system of claim 9, wherein said thermal control system is one or more of:
- a heating block, a peltier device, or a resistive heater.
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4. The apparatus of claim wherein the at least one semi-permeable membrane portion comprises a pore size of between about 10 μ
- m and about 100 μ
m.
- m and about 100 μ
Specification