Hydrocodone therapy

• US 6,491,945 B1
• Filed: 09/16/1994
• Issued: 12/10/2002
• Est. Priority Date: 09/16/1994
• Status: Expired due to Term

• Current Assignee: ALZA Corporation (Johnson & Johnson)
• Original Assignee: ALZA Corporation (Johnson & Johnson)
• Inventors: Barclay, Glen E., Childers, Jerry D., Kuczynski, Anthony L., Wong, Patrick S. L., Guittard, George V.
• Primary Examiner(s): MULLIS, JEFFREY C
• Application Number:
  US08/277,399
• Time in Patent Office: 3,007 Days
• Field of Search: 424/465, 424/468, 424/473
• US Class Current: 424/465
• CPC Class Codes: A61K 31/485 Morphinan derivatives, e.g. morphine, codeine
• CPC Class Codes: A61K 9/0004 Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
• CPC Class Codes: A61K 9/2031 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
• CPC Class Codes: A61K 9/2054 Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

A hydrocodone composition, a hydrocodone dosage form, and a method of administering hydrocodone are disclosed and indicated for hydrocodone therapy.

Claims

1. A therapeutic composition comprising 0.5 to 1250 mg of hydrocodone, 10 to 50 mg of alkali carboxymethylcellulose, 5 to 50 mg of hydroxypropylalkylcellulose and 0.01 to 5 mg of a lubricant.

2. The therapeutic composition according to claim 1, wherein the therapeutic composition comprises poly(vinylpyrrolidone).

3. The therapeutic composition according to claim 1, wherein the therapeutic composition comprises sorbitol.

4. The therapeutic composition according to claim 1, wherein a semipermeable wall with an exit passageway surrounds the therapeutic composition.