Multishot echo planar imaging fluoroscopic technique

• US 6,492,811 B1
• Filed: 11/22/2000
• Issued: 12/10/2002
• Est. Priority Date: 11/22/2000
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: Foxall, David L.
• Primary Examiner(s): ARANA, LOUIS M
• Application Number:
  US09/718,731
• Time in Patent Office: 748 Days
• Field of Search: 324/300, 324/306, 324/312, 324/314, 324/307, 324/309
• US Class Current: 324/309
• CPC Class Codes: G01R 33/5615 Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
• CPC Class Codes: G01R 33/5616 using gradient refocusing, e.g. EPI
• CPC Class Codes: G01R 33/56308 Characterization of motion or flow; Dynamic imaging

Abstract

A method of imaging a subject with an MRI scanner (10) includes positioning a region of interest of the subject in the MRI scanner (10) and executing an echo planar imaging pulse sequence therewith. A signal (S) produced by the echo planar imaging pulse sequence is received. The signal (S) includes first and second distinct sets of echos. Each echo (114a) in the first set of echos coincides with a positive polarity read gradient (112a) of the echo planar imaging pulse sequence and each echo (114b) in the second set of echos coincides with a negative polarity read gradient (112b) of the echo planar imaging pulse sequence. The method further includes collecting into a first k-space matrix data corresponding to the first set of echos and collecting into a second k-space matrix data corresponding to the second set of echos. A first image of the region of interest is reconstructed from the data in the first k-space matrix, and a second image of the region of interest is reconstructed from the data in the second k-space matrix. Preferably, the two images are temporally offset from one another, and cine or fluoroscopic imaging is achieved by alternating the frames thereof between iteratively produced first and second images.

Claims

1. A method of imaging a subject with an MRI scanner, said method comprising:

(a) positioning a region of interest of the subject in the MRI scanner;

(b) executing an echo planar imaging pulse sequence with the MRI scanner;

(c) receiving a signal produced by the echo planar imaging pulse sequence, said signal including first and second distinct sets of echos, wherein each echo in the first set of echos coincides with a positive polarity read gradient of the echo planar imaging pulse sequence and each echo in the second set of echos coincides with a negative polarity read gradient of the echo planar imaging pulse sequence;

(d) collecting, into a first k-space matrix, data corresponding to the first set of echos;

(e) collecting, into a second k-space matrix, data corresponding to the second set of echos;

(f) reconstructing a first image of the region of interest from the data in the first k-space matrix;

(g) reconstructing a second image of the region of interest from the data in the second k-space matrix, said second image being temporally offset form the first image;

(h) displaying said first and second images one after another; and

,

(i) repeating steps (b) through (h) iteratively to achieve one of cine and fluoroscopic imaging of the region of interest.

2. The method according to claim 1, wherein the reconstructing steps are carried out employing a Fourier transformation.

3. The method according to claim 1, wherein the reconstructing steps are carried out employing a partial Fourier transformation.

4. The method according to claim 1, wherein the first and second k-space matrices each include a plurality of interleaves which are successively filled with data.

5. The method according to claim 1, wherein the first and second images are temporally offset from one another by substantially one-half of a time-to-repeat, said time-to-repeat being equal to the time between two consecutive repetitions of step (b).

6. The method according to claim 1, wherein said first and second k-space matrices each have corresponding first and second ends, the data being collected into each of the first and second k-space matrix such that:

the first k-space matrix is filled in between the first and second ends, said filling beginning at a starting point substantially one-quarter of the way from the first end and continuing on to the second end, then continuing from the first end to the starting point; and

,

the second k-space matrix is filled in between the first and second ends, said filling beginning at a starting point substantially three-quarters of the way from the first end and continuing on to the second end, then continuing from the first end to the starting point.

7. The method according to claim 1, wherein said first and second k-space matrices each have corresponding first and second ends, the data being routed into each of the first and second k-space matrix such that:

the first k-space matrix is filled in between the first and second ends, said filling beginning at a starting point substantially one-quarter of the way from the first end and continuing on to the second end, then continuing from the first end to the starting point; and

,

the second k-space matrix is filled in between the first and second ends, said filling beginning at a starting point substantially three-quarters of the way from the first end and continuing on to the second end, then continuing from the first end to the starting point.

8. A magnetic resonance imaging apparatus comprising:

an MRI scanner in which a region of interest of a patient is positioned, said MRI scanner operable to carry out an echo planar imaging pulse sequence;

a receiver which observes a signal produced by the echo planar imaging pulse sequence, said signal including first and second distinct sets of echos, wherein each echo in the first set of echos coincides with a positive polarity read gradient of the echo planar imaging pulse sequence and each echo in the second set of echos coincides with a negative polarity read gradient of the echo planar imaging pulse sequence;

sorting means for routing into a first k-space matrix data corresponding to the first set of echos, and routing into a second k-space matrix data corresponding to the second set of echos;

a reconstruction processor which reconstructs a first image of the region of interest from the data in the first k-space matrix, and which reconstructs a second image of the region of interest from the data in the second k-space matrix, said first and second images being temporally offset from one another; and

,

a human viewable display which alternately displays both of the first and second images one after another to achieve one of cine and fluoroscopic imaging of the region of interest via iterative operation of the magnetic resonance imaging apparatus.

9. The magnetic resonance imaging apparatus of claim 8, wherein the reconstruction processor employs a Fourier transformation.

10. The magnetic resonance imaging apparatus of claim 8, wherein the reconstruction processor employs a partial Fourier transformation.

11. The magnetic resonance imaging apparatus of claim 8, wherein the echo planar imaging pulse sequence is a multi-shot sequence including a plurality of excitations.

12. The magnetic resonance imaging apparatus of claim 8, wherein the first and second k-space matrices each include a plurality of interleaves which are successively filled with data.

13. The magnetic resonance imaging apparatus according to claim 8, wherein the first and second images are temporally offset from one another by substantially one-half of a time-to-repeat, said time-to-repeat being equal to the time between a point in a first echo planar imaging pulse sequence to a corresponding point in a second consecutive echo planar imaging pulse sequence.

14. A method of imaging a patient with an MRI scanner, said method comprising:

(a) positioning a region of interest of the patient in the MRI scanner;

(b) executing a echo planar imaging pulse sequence with the MRI scanner;

(c) receiving a signal produced by the echo planar imaging pulse sequence, said signal including a plurality of echos, wherein each echo coincides with one of a positive and negative polarity read gradient of the echo planar imaging pulse sequence;

(d) sampling each echo to acquired data therefrom;

(e) sorting the acquired data into a plurality of distinct k-space matrices such that all the data in any one k-space matrix is acquired from echos coinciding with read gradients of like polarities;

(f) reconstructing a plurality of distinct images of the region of interest from corresponding data in each of the k-space matrices, said plurality of distinct images each being temporally offset from one another; and

,

(g) iteratively carrying out steps (b) through (f) to achieve one of cine and fluoroscopic imaging of the region of interest.

15. The method according to claim 14, wherein the reconstructing is carried out employing one of a full Fourier transformation and a partial Fourier transformation.

16. The method according to claim 14, wherein the echo planar imaging pulse sequence is a multi-shot sequence including a plurality of excitations.

17. The method according to claim 14, wherein the k-space matrices each include a plurality of interleaves which are successively filled with data.