Heart stimulation device with electrotonic inhibition

• US 6,493,585 B2
• Filed: 05/10/2001
• Issued: 12/10/2002
• Est. Priority Date: 01/28/1999
• Status: Active Grant

• Current Assignee: Sorin Biomedica Cardio Srl (LivaNova Plc)
• Original Assignee: Sorin Biomedica Cardio Srl (LivaNova Plc)
• Inventors: Marcelli, Emanuela, Gaggini, Guido, Plicchi, Gianni, Garberoglio, Bruno
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/852,874
• Publication Number:
  US 20010018600A1
• Time in Patent Office: 579 Days
• Field of Search: 607/4, 607/5, 607/9, 607/13, 607/14
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

Electrodes can generate electrical stimulation pulses at least one first intensity level and at least one second intensity level. The first and second intensity levels are above and below a given stimulation threshold, respectively. The synchronous or asynchronous delivery of second-level pulses enables the conduction of the atrioventricular node to be modulated by electrotonic effect, for example, to reduce ventricular frequency in the event of atrial fibrillation.

Claims

1. A device for providing stimulating pulses to the heart above and below a stimulation threshold, comprising:

first and second electrodes adapted to be implanted in the heart, a sensor configured to detect atrial fibrillation;

a processing unit in electrical communication with the first and second electrodes and the sensor, the processing unit being configured to provide first electrical stimulation pulses above the stimulation threshold to the first electrode and second electrical stimulation pulses below the stimulation threshold to the second electrode, the second electrical stimulation pulses being provided in response to a detection of atrial fibrillation.

2. The device of claim 1 wherein the second electrode includes the sensor.

3. The device of claim 1 wherein the processing unit if configured to vary at least one intensity parameter of the electrical stimulation pulses selected from the group of amplitude, duration, and frequency.

4. The device of claim 1 wherein the processing unit is configured to provide the second electrical stimulation pulses in the form of individual pulses.

5. The device of claim 1 wherein the processing unit is configured to provide the second electrical stimulation pulses synchronously according to spontaneous heart activity.

6. The device of claim 1 wherein the processing unit is configured to provide the second stimulation pulses in the form of repeated pulse trains.

7. The device of claim 1 wherein the processing unit is configured to provide the second stimulation pulses asynchronously according to spontaneous heart activity.

8. The device of claim 1 wherein the first electrode is configured to be implanted in a location effective to stimulate at least one of an atrium and a ventricle of the heart.

9. The method of claim 1 wherein the second electrode is configured to be implanted in the region of the atrioventricular node of the heart.

10. The method of claim 1 wherein the second electrode is configured to be implanted in a region effective to inhibit propagation of pulses from an atrium of the heart to a ventricle of the heart.